IL-33 signaling in sensory neurons promotes dry skin itch AM Trier, MR Mack, A Fredman, M Tamari, AM Ver Heul, Y Zhao, CJ Guo, ... Journal of Allergy and Clinical Immunology 149 (4), 1473-1480. e6, 2022 | 78 | 2022 |
Mechanosensitive TRPV4 is required for crystal-induced inflammation Z Lan, L Chen, J Feng, Z Xie, Z Liu, F Wang, P Liu, X Yue, L Du, Y Zhao, ... Annals of the rheumatic diseases 80 (12), 1604-1614, 2021 | 57 | 2021 |
A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain X Hu, L Du, S Liu, Z Lan, K Zang, J Feng, Y Zhao, X Yang, Z Xie, PL Wang, ... The Journal of Clinical Investigation 133 (5), 2023 | 49 | 2023 |
A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles F Li, Y Lang, Z Ji, Z Xia, Y Han, Y Cheng, G Liu, F Sun, Y Zhao, M Gao, ... Journal of Biological Chemistry 294 (1), 182-194, 2019 | 43 | 2019 |
Cryo-EM structure of a proton-activated chloride channel TMEM206 Z Deng, Y Zhao, J Feng, J Zhang, H Zhao, MJ Rau, JAJ Fitzpatrick, H Hu, ... Science Advances 7 (9), eabe5983, 2021 | 42 | 2021 |
Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity Z Xie, J Feng, TJ Hibberd, BN Chen, Y Zhao, K Zang, X Hu, X Yang, ... Neuron 111 (4), 526-538. e4, 2023 | 36 | 2023 |
Diverse structural features of potassium channels characterized by scorpion toxins as molecular probes Y Zhao, Z Chen, Z Cao, W Li, Y Wu Molecules 24 (11), 2045, 2019 | 28 | 2019 |
Human α‐defensins are immune‐related Kv1. 3 channel inhibitors: new support for their roles in adaptive immunity Z Xie, J Feng, W Yang, F Xiang, F Yang, Y Zhao, Z Cao, W Li, Z Chen, ... The FASEB Journal 29 (10), 4324-4333, 2015 | 27 | 2015 |
Kir2. 1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters W Yu, Z Wang, X Yu, Y Zhao, Z Xie, K Zhang, Z Chi, S Chen, T Xu, ... Nature communications 13 (1), 3544, 2022 | 18 | 2022 |
Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle J Feng, Y Zhao, Z Xie, K Zang, S Sviben, X Hu, JAJ Fitzpatrick, L Wen, ... Science translational medicine 14 (653), eabn4819, 2022 | 16 | 2022 |
Defensins, a novel type of animal toxin-like potassium channel inhibitor Y Zhao, Z Chen, Z Cao, W Li, Y Wu Toxicon 157, 101-105, 2019 | 15 | 2019 |
Human beta-defensin 1, a new animal toxin-like blocker of potassium channel J Feng, Z Xie, W Yang, Y Zhao, F Xiang, Z Cao, W Li, Z Chen, Y Wu Toxicon 113, 1-6, 2016 | 12 | 2016 |
Structural and functional analysis of human pannexin 2 channel Z He, Y Zhao, MJ Rau, JAJ Fitzpatrick, R Sah, H Hu, P Yuan Nature communications 14 (1), 1712, 2023 | 11 | 2023 |
Estrogen metabolites increase nociceptor hyperactivity in a mouse model of uterine pain Z Xie, J Feng, T Cai, R McCarthy, MD Eschbach, Y Wang, Y Zhao, Z Yi, ... JCI insight 7 (10), 2022 | 11 | 2022 |
Ion channel modulation by scorpion hemolymph and its defensin ingredients highlights origin of neurotoxins in telson formed in Paleozoic scorpions L Meng, Y Zhao, D Qu, Z Xie, X Guo, Z Zhu, Z Chen, L Zhang, W Li, Z Cao, ... International journal of biological macromolecules 148, 351-363, 2020 | 10 | 2020 |
MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel P Lu, Y Zhao, Z Xie, H Zhou, X Dong, GF Wu, BS Kim, J Feng, H Hu Cell reports 42 (4), 2023 | 9 | 2023 |
Mechanisms of Broad-Band UVB Irradiation‒Induced Itch in Mice L Cao, X Yue, Y Zhao, L Du, Z Xie, Y Yuan, S Zhang, F Li, J Feng, H Hu Journal of Investigative Dermatology 141 (10), 2499-2508. e3, 2021 | 9 | 2021 |
Pharmacological characterization of human beta-defensins 3 and 4 on potassium channels: Evidence of diversity in beta-defensin-potassium channel interactions Y Zhao, Z Xie, J Feng, W Li, Z Cao, Y Wu Peptides 108, 14-18, 2018 | 9 | 2018 |
Methotrexate, a small molecular scaffold targeting Kv1. 3 channel extracellular pore region Z Xie, Y Zhao, W Yang, W Li, Y Wu, Z Chen Biochemical and Biophysical Research Communications 532 (2), 265-270, 2020 | 7 | 2020 |
Triintsin, a human pathogenic fungus-derived defensin with broad-spectrum antimicrobial activity B Shen, J Song, Y Zhao, Y Zhang, G Liu, X Li, X Guo, W Li, Z Cao, Y Wu Peptides 107, 61-67, 2018 | 7 | 2018 |