Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations MC Baxa, EJ Haddadian, JM Jumper, KF Freed, TR Sosnick Proceedings of the National Academy of Sciences 111 (43), 15396-15401, 2014 | 117 | 2014 |
Benchmarking all-atom simulations using hydrogen exchange JJ Skinner, W Yu, EK Gichana, MC Baxa, JR Hinshaw, KF Freed, ... Proceedings of the National Academy of Sciences 111 (45), 15975-15980, 2014 | 82 | 2014 |
Characterizing the protein folding transition state using ψ analysis TR Sosnick, BA Krantz, RS Dothager, M Baxa Chemical reviews 106 (5), 1862-1876, 2006 | 62 | 2006 |
Quantifying the structural requirements of the folding transition state of protein A and other systems MC Baxa, KF Freed, TR Sosnick Journal of molecular biology 381 (5), 1362-1381, 2008 | 38 | 2008 |
Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core ZP Gates, MC Baxa, W Yu, JA Riback, H Li, B Roux, SBH Kent, ... Proceedings of the National Academy of Sciences 114 (9), 2241-2246, 2017 | 34 | 2017 |
Context and force field dependence of the loss of protein backbone entropy upon folding using realistic denatured and native state ensembles MC Baxa, EJ Haddadian, AK Jha, KF Freed, TR Sosnick Journal of the American Chemical Society 134 (38), 15929-15936, 2012 | 34 | 2012 |
Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similar MC Baxa, W Yu, AN Adhikari, L Ge, Z Xia, R Zhou, KF Freed, TR Sosnick Proceedings of the National Academy of Sciences 112 (27), 8302-8307, 2015 | 24 | 2015 |
HDX-MS performed on BtuB in E. coli outer membranes delineates the luminal domain’s allostery and unfolding upon B12 and TonB binding AM Zmyslowski, MC Baxa, IA Gagnon, TR Sosnick Proceedings of the National Academy of Sciences 119 (20), e2119436119, 2022 | 21 | 2022 |
Metal binding kinetics of bi-histidine sites used in ψ analysis: Evidence of high-energy protein folding intermediates GL Bosco, M Baxa, TR Sosnick Biochemistry 48 (13), 2950-2959, 2009 | 18 | 2009 |
A “Link‐Psi” strategy using crosslinking indicates that the folding transition state of ubiquitin is not very malleable AT Shandiz, MC Baxa, TR Sosnick Protein Science 21 (6), 819-827, 2012 | 14 | 2012 |
ψ-Constrained Simulations of Protein Folding Transition States: Implications for Calculating ϕ MC Baxa, KF Freed, TR Sosnick Journal of molecular biology 386 (4), 920-928, 2009 | 12 | 2009 |
Prediction and validation of a protein’s free energy surface using hydrogen exchange and (importantly) its denaturant dependence X Peng, M Baxa, N Faruk, JR Sachleben, S Pintscher, IA Gagnon, ... Journal of chemical theory and computation 18 (1), 550-561, 2021 | 10 | 2021 |
Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange W Yu, MC Baxa, I Gagnon, KF Freed, TR Sosnick Proceedings of the National Academy of Sciences 113 (17), 4747-4752, 2016 | 9 | 2016 |
Revealing what gets buried first in protein folding TR Sosnick, MC Baxa Proceedings of the National Academy of Sciences 110 (42), 16704-16705, 2013 | 4 | 2013 |
Engineered metal-binding sites to probe protein folding transition states: Psi analysis MC Baxa, TR Sosnick Protein Folding: Methods and Protocols, 31-63, 2022 | 2 | 2022 |
How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins MC Baxa, X Lin, CD Mukinay, S Chakravarthy, JR Sachleben, S Antilla, ... Protein Science 33 (5), e4986, 2024 | | 2024 |
Effects of hydrophobic sequence patterns on disordered protein conformational ensembles CD Mukinay, MC Baxa, TR Sosnick, PL Clark Biophysical Journal 123 (3), 169a-170a, 2024 | | 2024 |
Temperature-Dependent Fold-Switching Mechanism of the Circadian Clock Protein KaiB A Liwang, A Dinner, T Sosnick, LP Wang, CL Partch, N Zhang, D Sood, ... bioRxiv, 2024.05. 21.594594, 2024 | | 2024 |
Investigating the sequence properties that govern disorder and secretion of bacterial virulence proteins C Mukinay, M Baxa, TR Sosnick, PL Clark Biophysical Journal 122 (3), 201a, 2023 | | 2023 |
Characterizing the sequence determinants of protein disorder and its impact on virulence protein secretion C Mukinay, M Bowman, M Baxa, TR Sosnick, PL Clark Biophysical Journal 121 (3), 57a, 2022 | | 2022 |