Impaired surface expression of HLA‐DR, TLR2, TLR4, and TLR9 in Ex Vivo‐In Vitro stimulated monocytes from severely injured trauma patients D Heftrig, R Sturm, E Oppermann, K Kontradowitz, K Jurida, L Schimunek, ... Mediators of inflammation 2017 (1), 2608349, 2017 | 26 | 2017 |
An enrichment strategy yields seven novel single nucleotide polymorphisms associated with mortality and altered Th17 responses following blunt trauma L Schimunek, RA Namas, J Yin, D Liu, D Barclay, F El-Dehaibi, A Abboud, ... Shock 49 (3), 259-268, 2018 | 21 | 2018 |
A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice R Zamora, S Korff, Q Mi, D Barclay, L Schimunek, R Zucca, XD Arsiwalla, ... PLoS Computational Biology 14 (11), e1006582, 2018 | 20 | 2018 |
Comparative analysis of the regulatory T cells dynamics in peripheral blood in human and porcine polytrauma R Serve, R Sturm, L Schimunek, P Störmann, D Heftrig, MPJ Teuben, ... Frontiers in immunology 9, 435, 2018 | 20 | 2018 |
Leukotriene B4 indicates lung injury and on-going inflammatory changes after severe trauma in a porcine long-term model P Störmann, B Auner, L Schimunek, R Serve, K Horst, TP Simon, R Pfeifer, ... Prostaglandins, leukotrienes and essential fatty acids 127, 25-31, 2017 | 16 | 2017 |
Computational derivation of core, dynamic human blunt trauma inflammatory endotypes L Schimunek, H Lindberg, M Cohen, RA Namas, Q Mi, J Yin, D Barclay, ... Frontiers in immunology 11, 589304, 2021 | 15 | 2021 |
Early decreased TLR2 expression on monocytes is associated with their reduced phagocytic activity and impaired maturation in a porcine polytrauma model L Schimunek, R Serve, MPJ Teuben, P Störmann, B Auner, M Woschek, ... PloS one 12 (11), e0187404, 2017 | 12 | 2017 |
MPPED2 Polymorphism Is Associated With Altered Systemic Inflammation and Adverse Trauma Outcomes L Schimunek, RA Namas, J Yin, D Barclay, D Liu, F El-Dehaibi, A Abboud, ... Frontiers in genetics 10, 1115, 2019 | 11 | 2019 |
An aging-related single-nucleotide polymorphism is associated with altered clinical outcomes and distinct inflammatory profiles in aged blunt trauma patients AJ Lamparello, RA Namas, L Schimunek, M Cohen, F El-Dehaibi, J Yin, ... Shock 53 (2), 146-155, 2020 | 10 | 2020 |
Time Window-Based Platform for the Rapid Stratification of Blunt Trauma Patients into Distinct Outcome Cohorts GM Constantine, T Billiar, Q Mi, Y Vodovotz, R Namas, L Schimunek US Patent App. 15/971,519, 2018 | 3 | 2018 |
Quality control measures and validation in gene association studies: lessons for acute illness M Cohen, AJ Lamparello, L Schimunek, F El-Dehaibi, RA Namas, Y Xu, ... Shock 53 (3), 256-268, 2020 | 2 | 2020 |
Time window-based platform for the rapid stratification of blunt trauma patients into distinct outcome cohorts GM Constantine, T Billiar, Q Mi, R Namas, L Schimunek, Y Vodovotz US Patent 11,854,701, 2023 | | 2023 |
Posttraumatisch verminderte Expression von TLR2 ist mit verringerter Phagozytose-Leistung und gestörter Reifung von Monozyten assoziiert L Schimunek Universitätsbibliothek Johann Christian Senckenberg, 2023 | | 2023 |
SEVOFLURANE IS ASSOCIATED WITH WORSE CLINICAL OUTCOMES AND ALTERED INFLAMMATORY MARKERS IN BLUNT TRAUMA PATIENTS: PHARMACOGENOMIC ASSOCIATION WITH SINGLE NUCLEOTIDE … MA Cohen, L Schimunek, RA Namas, AM Kaynar, M Huber-Lang, ... ANESTHESIA AND ANALGESIA 128, 973-975, 2019 | | 2019 |
PROPOFOL-RELATED SINGLE NUCLEOTIDE POLYMORPHISMS ARE ASSOCIATED WITH ALTERED INFLAMMATORY PROFILES IN TRAUMA PATIENTS MA Cohen, L Schimunek, RA Namas, H Lindberg, F el-Dehaibi, ... SHOCK 49 (6), 59-60, 2018 | | 2018 |
ELEVATED CIRCULATING LEVELS OF INTERLEUKIN-27 ARE ASSOCIATED WITH NOSOCOMIAL INFECTION AND ALTERED INFLAMMATION IN HUMAN BLUNT TRAUMA RA Namas, L Schimunek, TR Billiar, Y Vodovotz SHOCK 49 (6), 125-125, 2018 | | 2018 |
A SINGLE NUCLEOTIDE POLYMORPHISM IN MPPED2 IS ASSOCIATED WITH INCREASED REQUIREMENT FOR MECHANICAL VENTILATION AND MORTALITY IN TRAUMA L Schimunek, R Namas, D Liu, J Yin, R Zamora, TR Billiar, Y Vodovotz SHOCK 47 (6), 15-15, 2017 | | 2017 |
ACUTE LUNG INJURY AFTER BLUNT CHEST TRAUMA AND HEMORRHAGIC SHOCK IS REDUCED BY ETHYL PYRUVATE VIA INHIBITION OF NF-kappa B AND HMGB1 M Perl, N Wagner, N Franz, S Dieteren, L Schimunek, I Marzi, B Relja SHOCK 47 (6), 102-102, 2017 | | 2017 |
DECREASED TLR2 EXPRESSION ON PORCINE MONOCYTES IN THE EARLY POST-TRAUMATIC PHASE IS ASSOCIATED WITH THEIR IMPAIRED MATURATION AND REDUCED PHAGOCYTIC ACTIVITY L Schimunek, R Serve, P Stoermann, M Woschek, K Horst, TP Simon, ... SHOCK 47 (6), 121-121, 2017 | | 2017 |
Precision Pharmacogenomics: Sevoflurane-related Single Nucleotide Polymorphism Rs1695 is Associated with Worse Clinical Outcomes and Altered Inflammatory Markers in Blunt … MA Cohen, L Schimunek, RN Student, H Lindberg, FED Student, ... | | |