| Copper induces cell death by targeting lipoylated TCA cycle proteins P Tsvetkov, S Coy, B Petrova, M Dreishpoon, A Verma, M Abdusamad, ... Science 375 (6586), 1254-1261, 2022 | 2135 | 2022 |
| Genetic and transcriptional evolution alters cancer cell line drug response U Ben-David, B Siranosian, G Ha, H Tang, Y Oren, K Hinohara, ... Nature 560 (7718), 325-330, 2018 | 836 | 2018 |
| A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73 G Asher, P Tsvetkov, C Kahana, Y Shaul Genes & development 19 (3), 316-321, 2005 | 430 | 2005 |
| Mitochondrial metabolism promotes adaptation to proteotoxic stress P Tsvetkov, A Detappe, K Cai, HR Keys, Z Brune, W Ying, P Thiru, ... Nature chemical biology 15 (7), 681-689, 2019 | 359 | 2019 |
| 20S proteasomal degradation of ornithine decarboxylase is regulated by NQO1 G Asher, Z Bercovich, P Tsvetkov, Y Shaul, C Kahana Molecular cell 17 (5), 645-655, 2005 | 197 | 2005 |
| The crystal structure of NAD (P) H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol G Asher, O Dym, P Tsvetkov, J Adler, Y Shaul Biochemistry 45 (20), 6372-6378, 2006 | 185 | 2006 |
| Inhibition of NAD (P) H: quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin P Tsvetkov, G Asher, V Reiss, Y Shaul, L Sachs, J Lotem Proceedings of the National Academy of Sciences 102 (15), 5535-5540, 2005 | 180 | 2005 |
| Ubiquitin-independent p53 proteasomal degradation P Tsvetkov, N Reuven, Y Shaul Cell Death & Differentiation 17 (1), 103-108, 2010 | 163 | 2010 |
| Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome P Tsvetkov, G Asher, A Paz, N Reuven, JL Sussman, I Silman, Y Shaul Proteins: Structure, Function, and Bioinformatics 70 (4), 1357-1366, 2008 | 132 | 2008 |
| BAG-1 associates with Hsc70· Tau complex and regulates the proteasomal degradation of Tau protein E Elliott, P Tsvetkov, I Ginzburg Journal of Biological Chemistry 282 (51), 37276-37284, 2007 | 132 | 2007 |
| The nanny model for IDPs P Tsvetkov, N Reuven, Y Shaul Nature chemical biology 5 (11), 778-781, 2009 | 131 | 2009 |
| A mutually inhibitory feedback loop between the 20S proteasome and its regulator, NQO1 O Moscovitz, P Tsvetkov, N Hazan, I Michaelevski, H Keisar, ... Molecular cell 47 (1), 76-86, 2012 | 113 | 2012 |
| The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1 Y Adamovich, A Shlomai, P Tsvetkov, KB Umansky, N Reuven, JL Estall, ... Molecular and cellular biology 33 (13), 2603-2613, 2013 | 111 | 2013 |
| The isolation and characterization of renal cancer initiating cells from human Wilms' tumour xenografts unveils new therapeutic targets N Pode‐Shakked, R Shukrun, M Mark‐Danieli, P Tsvetkov, S Bahar, ... EMBO molecular medicine 5 (1), 18-37, 2013 | 96 | 2013 |
| Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome P Tsvetkov, ML Mendillo, J Zhao, JE Carette, PH Merrill, D Cikes, ... elife 4, e08467, 2015 | 86 | 2015 |
| P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD (P) H: quinone oxidoreductase 1 G Asher, J Lotem, P Tsvetkov, V Reiss, L Sachs, Y Shaul Proceedings of the National Academy of Sciences 100 (25), 15065-15070, 2003 | 86 | 2003 |
| BIMEL, an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation CM Wiggins, P Tsvetkov, M Johnson, CL Joyce, CA Lamb, NJ Bryant, ... Journal of cell science 124 (6), 969-977, 2011 | 81 | 2011 |
| E3 ligase STUB1/CHIP regulates NAD (P) H: quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients P Tsvetkov, Y Adamovich, E Elliott, Y Shaul Journal of Biological Chemistry 286 (11), 8839-8845, 2011 | 76 | 2011 |
| A genetic tool to track protein aggregates and control prion inheritance GA Newby, S Kiriakov, E Hallacli, C Kayatekin, P Tsvetkov, CP Mancuso, ... Cell 171 (4), 966-979. e18, 2017 | 70 | 2017 |
| Susceptibility of p53 Unstructured N Terminus to 20 S Proteasomal Degradation Programs the Stress Response*♦ P Tsvetkov, N Reuven, C Prives, Y Shaul Journal of biological chemistry 284 (39), 26234-26242, 2009 | 68 | 2009 |
Yosef ShaulProfessor of Biology, Weizmann Institute of Science在 weizmann.ac.il 的电子邮件经过验证
