关注
Ronald Realubit
Ronald Realubit
Scientific Business Analyst, Regeneron Pharmaceuticals
在 regeneron.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Elucidating compound mechanism of action by network perturbation analysis
JH Woo, Y Shimoni, WS Yang, P Subramaniam, A Iyer, P Nicoletti, ...
Cell 162 (2), 441-451, 2015
3602015
A community computational challenge to predict the activity of pairs of compounds
M Bansal, J Yang, C Karan, MP Menden, JC Costello, H Tang, G Xiao, ...
Nature biotechnology 32 (12), 1213-1222, 2014
3312014
A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors
MJ Alvarez, PS Subramaniam, LH Tang, A Grunn, M Aburi, G Rieckhof, ...
Nature genetics 50 (7), 979-989, 2018
2052018
Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies
C Deng, MR Lipstein, L Scotto, XO Jirau Serrano, MA Mangone, S Li, ...
Blood, The Journal of the American Society of Hematology 129 (1), 88-99, 2017
1252017
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials
B Gold, M Pingle, SJ Brickner, N Shah, J Roberts, M Rundell, WC Bracken, ...
Proceedings of the National Academy of Sciences 109 (40), 16004-16011, 2012
1172012
PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
EC Bush, F Ray, MJ Alvarez, R Realubit, H Li, C Karan, A Califano, ...
Nature communications 8 (1), 105, 2017
1082017
Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy
M Porotto, G Orefice, CC Yokoyama, BA Mungall, R Realubit, ML Sganga, ...
Journal of virology 83 (10), 5148-5155, 2009
1022009
Preclinical pharmacologic evaluation of pralatrexate and romidepsin confirms potent synergy of the combination in a murine model of human T-cell lymphoma
S Jain, X Jirau-Serrano, KM Zullo, L Scotto, CF Palermo, SA Sastra, ...
Clinical Cancer Research 21 (9), 2096-2106, 2015
632015
Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma
AM Sonabend, AS Carminucci, B Amendolara, M Bansal, R Leung, L Lei, ...
Neuro-oncology 16 (9), 1210-1219, 2014
442014
Inhibition of NF-κB–Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma
G Ambrosini, C Do, B Tycko, RB Realubit, C Karan, E Musi, RD Carvajal, ...
Cancer research 79 (9), 2415-2425, 2019
412019
TSH receptor signaling abrogation by a novel small molecule
R Latif, RB Realubit, C Karan, M Mezei, TF Davies
Frontiers in endocrinology 7, 130, 2016
412016
Systematic, network-based characterization of therapeutic target inhibitors
Y Shen, MJ Alvarez, B Bisikirska, A Lachmann, R Realubit, S Pampou, ...
PLoS computational biology 13 (10), e1005599, 2017
272017
Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators
A Obradovic, C Ager, M Turunen, T Nirschl, M Khosravi-Maharlooei, ...
Cancer Cell 41 (5), 933-949. e11, 2023
252023
Bioactive compound screen for pharmacological enhancers of apolipoprotein E in primary human astrocytes
GM Finan, R Realubit, S Chung, D Lütjohann, N Wang, JR Cirrito, ...
Cell chemical biology 23 (12), 1526-1538, 2016
252016
OncoLoop: A network-based precision cancer medicine framework
A Vasciaveo, JM Arriaga, FN De Almeida, M Zou, EF Douglass Jr, ...
Cancer discovery 13 (2), 386-409, 2023
242023
The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies
JEL Diaz, ME Ahsen, T Schaffter, X Chen, RB Realubit, C Karan, ...
Elife 9, e52707, 2020
242020
The host cell virocheckpoint: identification and pharmacologic targeting of novel mechanistic determinants of coronavirus-mediated hijacked cell states
P Laise, G Bosker, X Sun, Y Shen, EF Douglass, C Karan, RB Realubit, ...
BioRxiv, 2020
152020
Reply to ‘H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines’
MJ Alvarez, P Yan, ML Alpaugh, M Bowden, E Sicinska, CW Zhou, ...
Nature genetics 51 (10), 1427-1428, 2019
152019
A Transcriptome-Based Precision Oncology Platform for Patient–Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies
PS Mundi, FS Dela Cruz, A Grunn, D Diolaiti, A Mauguen, AR Rainey, ...
Cancer discovery 13 (6), 1386-1407, 2023
142023
A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient
JB Chang, KM Quinnies, R Realubit, C Karan, JH Rand, NP Tatonetti
Scientific Reports 6 (1), 29387, 2016
142016
系统目前无法执行此操作,请稍后再试。
文章 1–20