The physics of cancer: the role of physical interactions and mechanical forces in metastasis D Wirtz, K Konstantopoulos, PC Searson Nature Reviews Cancer 11 (7), 512-522, 2011 | 1489 | 2011 |
Cancer cell motility: lessons from migration in confined spaces CD Paul, P Mistriotis, K Konstantopoulos Nature reviews cancer 17 (2), 131-140, 2017 | 616 | 2017 |
Water permeation drives tumor cell migration in confined microenvironments KM Stroka, H Jiang, SH Chen, Z Tong, D Wirtz, SX Sun, ... Cell 157 (3), 611-623, 2014 | 528 | 2014 |
Physical confinement alters tumor cell adhesion and migration phenotypes EM Balzer, Z Tong, CD Paul, WC Hung, KM Stroka, AE Boggs, SS Martin, ... The FASEB Journal 26 (10), 4045, 2012 | 312 | 2012 |
Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions OJT McCarty, SA Mousa, PF Bray, K Konstantopoulos Blood, The Journal of the American Society of Hematology 96 (5), 1789-1797, 2000 | 296 | 2000 |
Single-molecule analysis of cadherin-mediated cell-cell adhesion P Panorchan, MS Thompson, KJ Davis, Y Tseng, K Konstantopoulos, ... Journal of cell science 119 (1), 66-74, 2006 | 283 | 2006 |
A 3-D computational model predicts that cell deformation affects selectin-mediated leukocyte rolling S Jadhav, CD Eggleton, K Konstantopoulos Biophysical journal 88 (1), 96-104, 2005 | 281 | 2005 |
Cancer cells in transit: the vascular interactions of tumor cells K Konstantopoulos, SN Thomas Annual review of biomedical engineering 11 (1), 177-202, 2009 | 278 | 2009 |
Single molecule characterization of P-selectin/ligand binding W Hanley, O McCarty, S Jadhav, Y Tseng, D Wirtz, K Konstantopoulos Journal of biological chemistry 278 (12), 10556-10561, 2003 | 240 | 2003 |
Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation SH Chen, WC Hung, P Wang, C Paul, K Konstantopoulos Scientific reports 3 (1), 1870, 2013 | 234 | 2013 |
Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E-and L-selectin in shear flow SN Thomas, F Zhu, RL Schnaar, CS Alves, K Konstantopoulos Journal of biological chemistry 283 (23), 15647-15655, 2008 | 227 | 2008 |
Venous Levels of Shear Support Neutrophil-Platelet Adhesion and Neutrophil Aggregation in Blood via P-Selectin and β2-Integrin K Konstantopoulos, S Neelamegham, AR Burns, E Hentzen, GS Kansas, ... Circulation 98 (9), 873-882, 1998 | 218 | 1998 |
Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses C Pardo-Pastor, F Rubio-Moscardo, M Vogel-González, SA Serra, ... Proceedings of the National Academy of Sciences 115 (8), 1925-1930, 2018 | 199 | 2018 |
Circulating platelets show increased activation in patients with acute cerebral ischemia JA Zeller, D Tschoepe, C Kessler Thrombosis and haemostasis 81 (03), 373-377, 1999 | 190 | 1999 |
A physical sciences network characterization of non-tumorigenic and metastatic cells Scientific reports 3 (1), 1449, 2013 | 175 | 2013 |
Confinement sensing and signal optimization via Piezo1/PKA and myosin II pathways WC Hung, JR Yang, CL Yankaskas, BS Wong, PH Wu, C Pardo-Pastor, ... Cell reports 15 (7), 1430-1441, 2016 | 172 | 2016 |
Distinct signaling mechanisms regulate migration in unconfined versus confined spaces WC Hung, SH Chen, CD Paul, KM Stroka, YC Lo, JT Yang, ... Journal of cell biology 202 (5), 807-824, 2013 | 171 | 2013 |
Chemotaxis of cell populations through confined spaces at single-cell resolution ZQ Tong, EM Balzer, MR Dallas, WC Hung, KJ Stebe, K Konstantopoulos PloS one 7 (1), e29211, 2012 | 171 | 2012 |
Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis ZR Healy, NH Lee, X Gao, MB Goldring, P Talalay, TW Kensler, ... Proceedings of the National Academy of Sciences 102 (39), 14010-14015, 2005 | 170 | 2005 |
E-selectin receptors on human leukocytes L Nimrichter, MM Burdick, K Aoki, W Laroy, MA Fierro, SA Hudson, ... Blood, The Journal of the American Society of Hematology 112 (9), 3744-3752, 2008 | 168 | 2008 |