ER-directed TREX1 limits cGAS activation at micronuclei L Mohr, E Toufektchan, P von Morgen, K Chu, A Kapoor, J Maciejowski Molecular cell 81 (4), 724-738. e9, 2021 | 157 | 2021 |
APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis J Maciejowski, A Chatzipli, A Dananberg, K Chu, E Toufektchan, ... Nature genetics 52 (9), 884-890, 2020 | 141 | 2020 |
Mechanisms of APOBEC3 mutagenesis in human cancer cells M Petljak, A Dananberg, K Chu, EN Bergstrom, J Striepen, P von Morgen, ... Nature 607 (7920), 799-807, 2022 | 129 | 2022 |
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants FJ Sánchez-Rivera, BJ Diaz, ER Kastenhuber, H Schmidt, A Katti, ... Nature biotechnology 40 (6), 862-873, 2022 | 59 | 2022 |
Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH J Simón, N Goikoetxea-Usandizaga, M Serrano-Maciá, ... Journal of Hepatology 75 (1), 34-45, 2021 | 27 | 2021 |
The APOBEC3A deaminase drives episodic mutagenesis in cancer cells M Petljak, K Chu, A Dananberg, EN Bergstrom, P Morgen, LB Alexandrov, ... BioRxiv, 2021.02. 14.431145, 2021 | 13 | 2021 |
Adding new dimensions to 3D cancer models K Chu, LE Dow Cancer Research 84 (6), 798-799, 2024 | | 2024 |
Hepatic magnesium accumulation upon cyclin M4 (CNNM4) silencing improves NASH J Simon, N Goikoetxea, M Serrano-Macia, D Fernandez Ramos, ... JOURNAL OF HEPATOLOGY 75, S612-S612, 2021 | | 2021 |
The APOBEC3A deaminase drives episodic mutagenesis in cancer cells J Maciejowski, M Petljak, K Chu, A Dananberg, E Bergstrom, ... | | 2021 |
TREX1-induced chromosome fragmentation at the interface of innate immunity and genomic instability L Mohr, K Chu, J Maciejowski The Journal of Immunology 204 (1_Supplement), 162.5-162.5, 2020 | | 2020 |