BACE1 regulates voltage-gated sodium channels and neuronal activity DY Kim, BW Carey, H Wang, LAM Ingano, AM Binshtok, MH Wertz, ... Nature cell biology 9 (7), 755-764, 2007 | 382 | 2007 |
Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits B Akten, MJ Kye, LT Hao, MH Wertz, S Singh, D Nie, J Huang, ... Proceedings of the National Academy of Sciences 108 (25), 10337-10342, 2011 | 249 | 2011 |
SMN regulates axonal local translation via miR-183/mTOR pathway MJ Kye, ED Niederst, MH Wertz, ICG Gonçalves, B Akten, KZ Dover, ... Human molecular genetics 23 (23), 6318-6331, 2014 | 156 | 2014 |
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1 A Di Nardo, MH Wertz, E Kwiatkowski, PT Tsai, JD Leech, ... Human molecular genetics 23 (14), 3865-3874, 2014 | 106 | 2014 |
Genome-wide in vivo CNS screening identifies genes that modify CNS neuronal survival and mHTT toxicity MH Wertz, MR Mitchem, SS Pineda, LJ Hachigian, H Lee, V Lau, ... Neuron 106 (1), 76-89. e8, 2020 | 75 | 2020 |
Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy MH Wertz, K Winden, P Neveu, SY Ng, E Ercan, M Sahin Human molecular genetics 25 (11), 2168-2181, 2016 | 51 | 2016 |
Characterization of the nuclear localization signal of high risk HPV16 E2 protein K Klucevsek, M Wertz, J Lucchi, A Leszczynski, J Moroianu Virology 360 (1), 191-198, 2007 | 26 | 2007 |
Interleukin-6 deficiency exacerbates Huntington’s disease model phenotypes MH Wertz, SS Pineda, H Lee, R Kulicke, M Kellis, M Heiman Molecular neurodegeneration 15, 1-8, 2020 | 25 | 2020 |
Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis SW Kong, M Sahin, CD Collins, MH Wertz, MG Campbell, JD Leech, ... Molecular Autism 5, 1-11, 2014 | 22 | 2014 |
Developing therapies for spinal muscular atrophy MH Wertz, M Sahin Annals of the New York Academy of Sciences 1366 (1), 5-19, 2016 | 21 | 2016 |
Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin L Megret, B Gris, S Sasidharan Nair, J Cevost, M Wertz, J Aaronson, ... Elife 10, e64984, 2021 | 7 | 2021 |
The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells DY Kim, MH Wertz, V Gautam, C D'avanzo, R Bhattacharyya, DM Kovacs Neurodegenerative Diseases 13 (2-3), 64-68, 2014 | 5 | 2014 |
Genome-wide genetic screening in the mammalian CNS MH Wertz, M Heiman Genome Editing in Neurosciences, 31-39, 2017 | 2 | 2017 |
Neuronal Tsc1/2 Complex Controls Autophagy Through AMPK-Dependent Regulation Of ULK1 AD NARDO, MH Wertz, E Kwiatkowski, PT Tsai, JD Leech, ... Human Molecular Genetics 23 (14), 1-10, 2014 | 1 | 2014 |
A39 Precision machine-learning identifies a new paradigm along with a target database for therapeutic discovery in Huntington’s disease: molecular reprogramming to re-instate … L Megret, B Gris, SS Nai, J Cevost, M Wertz, J Aaronson, J Rosinski, ... Journal of Neurology, Neurosurgery & Psychiatry 93 (Suppl 1), A14-A14, 2022 | | 2022 |
A03 Precise machine-learning suggests that neuronal death in HD is mainly driven by the loss of homeostatic responses L Mégret, B Gris, SS Nair, J Cevost, M Wertz, J Aaronson, J Rosinski, ... Journal of Neurology, Neurosurgery & Psychiatry 92 (Suppl 1), A1-A2, 2021 | | 2021 |
Aberrant microRNA expression in spinal muscular atrophy motor neurons MH Wertz Harvard University, 2015 | | 2015 |