| The role of adipose tissue senescence in obesity-and ageing-related metabolic disorders Z Liu, KKL Wu, X Jiang, A Xu, KKY Cheng Clinical science 134 (2), 315-330, 2020 | 132 | 2020 |
| NLRP3 inflammasome activation in adipose tissues and its implications on metabolic diseases KKL Wu, SWM Cheung, KKY Cheng International Journal of Molecular Sciences 21 (11), 4184, 2020 | 70 | 2020 |
| The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages KKL Wu, KK Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng Nature communications 12 (1), 6637, 2021 | 56 | 2021 |
| The dysfunctional MDM2–p53 axis in adipocytes contributes to aging-related metabolic complications by induction of lipodystrophy Z Liu, L Jin, JK Yang, B Wang, KKL Wu, P Hallenborg, A Xu, KKY Cheng Diabetes 67 (11), 2397-2409, 2018 | 48 | 2018 |
| Activation of hypothalamic RIP‐Cre neurons promotes beiging of WAT via sympathetic nervous system B Wang, A Li, X Li, PWL Ho, D Wu, X Wang, Z Liu, KKL Wu, SSY Yau, ... EMBO reports 19 (4), e44977, 2018 | 31 | 2018 |
| Hepatic MDM2 Causes Metabolic Associated Fatty Liver Disease by Blocking Triglyceride‐VLDL Secretion via ApoB Degradation H Lin, L Wang, Z Liu, K Long, M Kong, D Ye, X Chen, K Wang, KKL Wu, ... Advanced Science 9 (20), 2200742, 2022 | 27 | 2022 |
| APPL1 prevents pancreatic beta cell death and inflammation by dampening NFκB activation in a mouse model of type 1 diabetes X Jiang, Y Zhou, KKL Wu, Z Chen, A Xu, KKY Cheng Diabetologia 60, 464-474, 2017 | 20 | 2017 |
| Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77–FGF21 pathway P Ahuja, X Bi, CF Ng, MCL Tse, M Hang, BPS Pang, ECY Iu, WS Chan, ... Hepatology 77 (1), 213-229, 2023 | 12 | 2023 |
| A new role of the early endosome in restricting NLRP3 inflammasome via mitophagy KKL Wu, KKY Cheng Autophagy 18 (6), 1475-1477, 2022 | 10 | 2022 |
| Screening repurposed antiviral small molecules as antimycobacterial compounds by a lux-based phoP promoter-reporter platform L Zhu, AWT Lee, KKL Wu, P Gao, KKG Tam, R Rajwani, GC Chaburte, ... Antibiotics 11 (3), 369, 2022 | 6 | 2022 |
| MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1α pathways in mice KK Wu, X Xu, M Wu, X Li, M Hoque, GHY Li, Q Lian, K Long, T Zhou, ... Nature Communications 15 (1), 8624, 2024 | 4 | 2024 |
| 248-LB: Deficiency of APPL1 in Macrophages Triggers Adipose Tissue Inflammation and Insulin Resistance by Potentiating NLRP3 Inflammasome Activation KKL WU, A XU, KK CHENG Diabetes 68 (Supplement_1), 2019 | 2 | 2019 |
| Hypothalamic APPL2 acts as a key mediator in maintaining energy homeostasis by controlling thermogenesis in subcutaneous white adipose tissue B Wang, KKY Cheng, X Li, KKL Wu, L Jin, X Jiang, Z Liu, Y Zhou, A Xu The FASEB Journal 30, lb720-lb720, 2016 | 2 | 2016 |
| Construction of lux-based promoter-reporter platforms in Mycobacterium bovis BCG for screening of drug repurposing small-molecule compounds as new anti … L Zhu, AWT Lee, KKL Wu, P Gao, KKG Tam, R Rajwani, GC Chaburte, ... bioRxiv, 2021.11. 05.467536, 2021 | | 2021 |
| Ablation of the adaptor protein APPL2 in hypothalamic RIP-Cre neurons by promotes beiging of WAT via sympathetic nervous system B Wang, A Li, X Li, WL Ho, D Wu, X Wang, K Wu, S Yau, A Xu, K Cheng Singapore Symposium on Metabolic Diseases, 2017, 2017 | | 2017 |
