Nuclear magnetic resonance of paramagnetic metalloproteins I Bertini, P Turano, AJ Vila Chemical reviews 93 (8), 2833-2932, 1993 | 509 | 1993 |
Metallo-β-lactamases: novel weaponry for antibiotic resistance in bacteria MW Crowder, J Spencer, AJ Vila Accounts of chemical research 39 (10), 721-728, 2006 | 474 | 2006 |
Mitochondrial cytochrome c oxidase biogenesis: Recent developments A Timón-Gómez, E Nývltová, LA Abriata, AJ Vila, J Hosler, A Barrientos Seminars in cell & developmental biology 76, 163-178, 2018 | 319 | 2018 |
Can ceftazidime-avibactam and aztreonam overcome β-lactam resistance conferred by metallo-β-lactamases in Enterobacteriaceae? S Marshall, AM Hujer, LJ Rojas, KM Papp-Wallace, RM Humphries, ... Antimicrobial agents and chemotherapy 61 (4), 10.1128/aac. 02243-16, 2017 | 276 | 2017 |
Membrane anchoring stabilizes and favors secretion of New Delhi metallo-β-lactamase LJ González, G Bahr, TG Nakashige, EM Nolan, RA Bonomo, AJ Vila Nature chemical biology 12 (7), 516-522, 2016 | 173 | 2016 |
Overcoming differences: the catalytic mechanism of metallo-β-lactamases MR Meini, LI Llarrull, AJ Vila FEBS letters 589 (22), 3419-3432, 2015 | 169 | 2015 |
Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes P Hinchliffe, MM González, MF Mojica, JM González, V Castillo, C Saiz, ... Proceedings of the National Academy of Sciences 113 (26), E3745-E3754, 2016 | 151 | 2016 |
The iron-sulfur cluster (Fe4S4) centers in ferredoxins studied through proton and carbon hyperfine coupling. Sequence-specific assignments of cysteines in ferredoxins from … I Bertini, F Capozzi, C Luchinat, M Piccioli, AJ Vila Journal of the American Chemical Society 116 (2), 651-660, 1994 | 150 | 1994 |
Spectroscopic characterization of a binuclear metal site in Bacillus cereus β-lactamase II EG Orellano, JE Girardini, JA Cricco, EA Ceccarelli, AJ Vila Biochemistry 37 (28), 10173-10180, 1998 | 148 | 1998 |
The urgent need for metallo-β-lactamase inhibitors: an unattended global threat MF Mojica, MA Rossi, AJ Vila, RA Bonomo The Lancet Infectious Diseases 22 (1), e28-e34, 2022 | 145 | 2022 |
Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design G Bahr, LJ Gonzalez, AJ Vila Chemical Reviews 121 (13), 7957-8094, 2021 | 144 | 2021 |
Mechanism of CuA assembly LA Abriata, L Banci, I Bertini, S Ciofi-Baffoni, P Gkazonis, GA Spyroulias, ... Nature chemical biology 4 (10), 599-601, 2008 | 141 | 2008 |
A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases MN Lisa, AR Palacios, M Aitha, MM González, DM Moreno, MW Crowder, ... Nature communications 8 (1), 538, 2017 | 128 | 2017 |
Structural basis of lipid biosynthesis regulation in Gram‐positive bacteria GE Schujman, M Guerin, A Buschiazzo, F Schaeffer, LI Llarrull, G Reh, ... The EMBO journal 25 (17), 4074-4083, 2006 | 125 | 2006 |
Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility PE Tomatis, SM Fabiane, F Simona, P Carloni, BJ Sutton, AJ Vila Proceedings of the National Academy of Sciences 105 (52), 20605-20610, 2008 | 121 | 2008 |
Bisthiazolidines: a substrate-mimicking scaffold as an inhibitor of the NDM-1 carbapenemase MM González, M Kosmopoulou, MF Mojica, V Castillo, P Hinchliffe, ... ACS infectious diseases 1 (11), 544-554, 2015 | 118 | 2015 |
Nitration of solvent-exposed tyrosine 74 on cytochrome c triggers heme iron-methionine 80 bond disruption: Nuclear magnetic resonance and optical spectroscopy studies LA Abriata, A Cassina, V Tortora, M Marín, JM Souza, L Castro, AJ Vila, ... Journal of Biological Chemistry 284 (1), 17-26, 2009 | 117 | 2009 |
Sensitive EDTA-based microbiological assays for detection of metallo-β-lactamases in nonfermentative gram-negative bacteria P Marchiaro, MA Mussi, V Ballerini, F Pasteran, AM Viale, AJ Vila, ... Journal of Clinical Microbiology 43 (11), 5648-5652, 2005 | 117 | 2005 |
Mimicking natural evolution in metallo-β-lactamases through second-shell ligand mutations PE Tomatis, RM Rasia, L Segovia, AJ Vila Proceedings of the National Academy of Sciences 102 (39), 13761-13766, 2005 | 111 | 2005 |
Water-assisted reaction mechanism of monozinc β-lactamases M Dal Peraro, LI Llarrull, U Rothlisberger, AJ Vila, P Carloni Journal of the American Chemical Society 126 (39), 12661-12668, 2004 | 108 | 2004 |