A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly M Koegl, T Hoppe, S Schlenker, HD Ulrich, TU Mayer, S Jentsch Cell 96 (5), 635-644, 1999 | 1454 | 1999 |
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors S Pfefferle, J Schöpf, M Kögl, CC Friedel, MA Müller, J Carbajo-Lozoya, ... PLoS pathogens 7 (10), e1002331, 2011 | 456 | 2011 |
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design W Farnaby, M Koegl, MJ Roy, C Whitworth, E Diers, N Trainor, D Zollman, ... Nature chemical biology 15 (7), 672-680, 2019 | 422 | 2019 |
Drugging an undruggable pocket on KRAS D Kessler, M Gmachl, A Mantoulidis, LJ Martin, A Zoephel, M Mayer, ... Proceedings of the National Academy of Sciences 116 (32), 15823-15829, 2019 | 374 | 2019 |
The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors. S Roche, M Koegl, SA Courtneidge Proceedings of the National Academy of Sciences 91 (19), 9185-9189, 1994 | 352 | 1994 |
Csk inhibition of c‐Src activity requires both the SH2 and SH3 domains of Src. G Superti‐Furga, S Fumagalli, M Koegl, SA Courtneidge, G Draetta The EMBO journal 12 (7), 2625-2634, 1993 | 331 | 1993 |
DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases S Roche, M Koegl, MV Barone, MF Roussel, SA Courtneidge Molecular and cellular biology 15 (2), 1102-1109, 1995 | 291 | 1995 |
Iterative design and optimization of initially inactive proteolysis targeting chimeras (PROTACs) identify VZ185 as a potent, fast, and selective von Hippel–Lindau (VHL) based … V Zoppi, SJ Hughes, C Maniaci, A Testa, T Gmaschitz, C Wieshofer, ... Journal of medicinal chemistry 62 (2), 699-726, 2018 | 282 | 2018 |
CEP152 is a genome maintenance protein disrupted in Seckel syndrome E Kalay, G Yigit, Y Aslan, KE Brown, E Pohl, LS Bicknell, H Kayserili, Y Li, ... Nature genetics 43 (1), 23-26, 2011 | 270 | 2011 |
Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif M Koegl, P Zlatkine, SC Ley, SA Courtneidge, AI Magee Biochemical Journal 303 (3), 749-753, 1994 | 269 | 1994 |
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome MJ Taussig, O Stoevesandt, CAK Borrebaeck, AR Bradbury, D Cahill, ... Nature methods 4 (1), 13-17, 2007 | 258 | 2007 |
Sequence Requirements for Binding of Src Family Tyrosine Kinases to Activated Growth Factor Receptors (∗) G Alonso, M Koegl, N Mazurenko, SA Courtneidge Journal of Biological Chemistry 270 (17), 9840-9848, 1995 | 242 | 1995 |
Evolutionarily conserved herpesviral protein interaction networks E Fossum, CC Friedel, SV Rajagopala, B Titz, A Baiker, T Schmidt, ... PLoS pathogens 5 (9), e1000570, 2009 | 229 | 2009 |
Structure-based design of an in vivo active selective BRD9 inhibitor LJ Martin, M Koegl, G Bader, XL Cockcroft, O Fedorov, D Fiegen, ... Journal of medicinal chemistry 59 (10), 4462-4475, 2016 | 216 | 2016 |
Identification of farnesoid X receptor β as a novel mammalian nuclear receptor sensing lanosterol K Otte, H Kranz, I Kober, P Thompson, M Hoefer, B Haubold, B Remmel, ... Molecular and cellular biology 23 (3), 864-872, 2003 | 202 | 2003 |
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition AF Hohmann, LJ Martin, JL Minder, JS Roe, J Shi, S Steurer, G Bader, ... Nature chemical biology 12 (9), 672-679, 2016 | 173 | 2016 |
Chemically induced degradation of the oncogenic transcription factor BCL6 N Kerres, S Steurer, S Schlager, G Bader, H Berger, M Caligiuri, C Dank, ... Cell reports 20 (12), 2860-2875, 2017 | 166 | 2017 |
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins M Albers, H Kranz, I Kober, C Kaiser, M Klink, J Suckow, R Kern, M Koegl Molecular & Cellular Proteomics 4 (2), 205-213, 2005 | 162 | 2005 |
Improving yeast two-hybrid screening systems M Koegl, P Uetz Briefings in Functional Genomics and Proteomics 6 (4), 302-312, 2007 | 142 | 2007 |
Highly selective PTK2 proteolysis targeting chimeras to probe focal adhesion kinase scaffolding functions J Popow, H Arnhof, G Bader, H Berger, A Ciulli, D Covini, C Dank, ... Journal of Medicinal Chemistry 62 (5), 2508-2520, 2019 | 126 | 2019 |