The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ... Nature 486 (7403), 346-352, 2012 | 6037 | 2012 |
The evolutionary history of 2,658 cancers M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ... Nature 578 (7793), 122-128, 2020 | 902 | 2020 |
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions F De Sousa E Melo, X Wang, M Jansen, E Fessler, A Trinh, ... Nature medicine 19 (5), 614-618, 2013 | 867 | 2013 |
Acetylcysteine for prevention of contrast nephropathy: meta-analysis R Birck, S Krzossok, F Markowetz, P Schnülle, FJ van der Woude, ... The Lancet 362 (9384), 598-603, 2003 | 710 | 2003 |
Patterns of immune infiltration in breast cancer and their clinical implications: a gene-expression-based retrospective study HR Ali, L Chlon, PDP Pharoah, F Markowetz, C Caldas PLoS medicine 13 (12), e1002194, 2016 | 558 | 2016 |
Inferring cellular networks–a review F Markowetz, R Spang BMC bioinformatics 8, 1-17, 2007 | 527 | 2007 |
Quantitative Image Analysis of Cellular Heterogeneity in Breast Tumors Complements Genomic Profiling Y Yuan, H Failmezger, OM Rueda, HR Ali, S Gräf, SF Chin, RF Schwarz, ... Science Translational Medicine 4 (157), 157ra143-157ra143, 2012 | 465 | 2012 |
Cancer evolution: mathematical models and computational inference N Beerenwinkel, RF Schwarz, M Gerstung, F Markowetz Systematic biology 64 (1), e1-e25, 2015 | 409 | 2015 |
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis RF Schwarz, CKY Ng, SL Cooke, S Newman, J Temple, AM Piskorz, ... PLoS medicine 12 (2), e1001789, 2015 | 403 | 2015 |
Copy number signatures and mutational processes in ovarian carcinoma G Macintyre, TE Goranova, D De Silva, D Ennis, AM Piskorz, M Eldridge, ... Nature genetics 50 (9), 1262-1270, 2018 | 393 | 2018 |
Systems-level dynamic analyses of fate change in murine embryonic stem cells R Lu, F Markowetz, RD Unwin, JT Leek, EM Airoldi, BD MacArthur, ... Nature 462 (7271), 358-362, 2009 | 334 | 2009 |
OncoNEM: inferring tumor evolution from single-cell sequencing data EM Ross, F Markowetz Genome biology 17, 1-14, 2016 | 232 | 2016 |
Master regulators of FGFR2 signalling and breast cancer risk MNC Fletcher, MAA Castro, X Wang, I De Santiago, M O’Reilly, SF Chin, ... Nature communications 4 (1), 2464, 2013 | 210 | 2013 |
Regulators of genetic risk of breast cancer identified by integrative network analysis MAA Castro, I de Santiago, TM Campbell, C Vaughn, TE Hickey, E Ross, ... Nature genetics 48 (1), 12-21, 2016 | 180 | 2016 |
Diverse epigenetic strategies interact to control epidermal differentiation KW Mulder, X Wang, C Escriu, Y Ito, RF Schwarz, J Gillis, G Sirokmany, ... Nature cell biology 14 (7), 753-763, 2012 | 170 | 2012 |
Phylogenetic quantification of intra-tumour heterogeneity RF Schwarz, A Trinh, B Sipos, JD Brenton, N Goldman, F Markowetz PLoS computational biology 10 (4), e1003535, 2014 | 168 | 2014 |
Practical and robust identification of molecular subtypes in colorectal cancer by immunohistochemistry A Trinh, K Trumpi, F De Sousa E Melo, X Wang, JH De Jong, E Fessler, ... Clinical cancer research 23 (2), 387-398, 2017 | 166 | 2017 |
All biology is computational biology F Markowetz PLoS biology 15 (3), e2002050, 2017 | 145 | 2017 |
BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies K Yuan, T Sakoparnig, F Markowetz, N Beerenwinkel Genome biology 16, 1-16, 2015 | 139 | 2015 |
HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens X Wang, C Terfve, JC Rose, F Markowetz Bioinformatics 27 (6), 879-880, 2011 | 134 | 2011 |