| Complex effects of nucleotide variants in a mammalian cis-regulatory element JC Kwasnieski, I Mogno, CA Myers, JC Corbo, BA Cohen Proceedings of the National Academy of Sciences 109 (47), 19498-19503, 2012 | 289 | 2012 |
| High-throughput functional testing of ENCODE segmentation predictions JC Kwasnieski, C Fiore, HG Chaudhari, BA Cohen Genome research 24 (10), 1595-1602, 2014 | 279 | 2014 |
| mRNA poly (A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos SW Eichhorn, AO Subtelny, I Kronja, JC Kwasnieski, TL Orr-Weaver, ... Elife 5, e16955, 2016 | 160 | 2016 |
| Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants I Mogno, JC Kwasnieski, BA Cohen Genome research 23 (11), 1908-1915, 2013 | 112 | 2013 |
| A simple grammar defines activating and repressing cis-regulatory elements in photoreceptors MA White, JC Kwasnieski, CA Myers, SQ Shen, JC Corbo, BA Cohen Cell Reports 17 (5), 1247-1254, 2016 | 80 | 2016 |
| Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns JC Kwasnieski, TL Orr-Weaver, DP Bartel Genome research 29 (7), 1188-1197, 2019 | 66 | 2019 |
| Overcoming immunological challenges limiting capsid-mediated gene therapy with machine learning AZ Wec, KS Lin, JC Kwasnieski, S Sinai, J Gerold, ED Kelsic Frontiers in Immunology 12, 674021, 2021 | 18 | 2021 |
| Efficient design of optimized AAV capsids using multi-property machine learning models trained across cells, organs and species S Abestesh, I Akartuna, A Brown, M Cramer, F Damani, J Gerold, J Gorns, ... MOLECULAR THERAPY 29 (4), 12-12, 2021 | 1 | 2021 |
| Dyno eCap 1 capsid: an optimized IVT delivered AAV capsid with improved retinal cell targeting for wetAMD, GA, glaucoma and IRD gene therapies A Miles, H Turunen, B Diaz-Rohrer, S Hilton, S Chen, K Maryak, S Sinai, ... Investigative Ophthalmology & Visual Science 65 (7), 6085-6085, 2024 | | 2024 |
| Determining Cell-Type Specific Distribution of AAV Variants in NHP Retina Using Single-Nuclei RNA Sequencing A Ghosh, I Brenckle, S Wolock, C Sengel, S Lapan, JC Kwasnieski, ... MOLECULAR THERAPY 30 (4), 440-440, 2022 | | 2022 |
| Machine-Guided Design Reveals AAV Variants Efficient in Transducing NHP Retina After Intravitreal Delivery HT Turunen, M Cramer, J Gerold, H Kuchwara, JC Kwasnieski, S Lapan, ... MOLECULAR THERAPY 30 (4), 555-555, 2022 | | 2022 |
| AAV Capsid Property Estimation Is Improved by Combining Single-Molecule ID Tags and Hierarchical Bayesian Modeling of Experimental Processes K Lin, J Otwinowski, B Tobin, S Wolock, J Kwasnieski, C Sengel, R Ogurlu, ... MOLECULAR THERAPY 29 (4), 98-98, 2021 | | 2021 |
| cis-Regulation in the Mammalian Rod Photoreceptor JC Kwasnieski Washington University in St. Louis, 2014 | | 2014 |
