Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes G Blum, G Von Degenfeld, MJ Merchant, HM Blau, M Bogyo Nature chemical biology 3 (10), 668-677, 2007 | 510 | 2007 |
Dynamic imaging of protease activity with fluorescently quenched activity-based probes G Blum, SR Mullins, K Keren, M Fonovič, C Jedeszko, MJ Rice, BF Sloane, ... Nature chemical biology 1 (4), 203-209, 2005 | 402 | 2005 |
Activity-based probes that target diverse cysteine protease families D Kato, KM Boatright, AB Berger, T Nazif, G Blum, C Ryan, KAH Chehade, ... Nature chemical biology 1 (1), 33-38, 2005 | 385 | 2005 |
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes LE Edgington, AB Berger, G Blum, VE Albrow, MG Paulick, N Lineberry, ... Nature medicine 15 (8), 967-973, 2009 | 327 | 2009 |
Macrophage subpopulations are essential for infarct repair with and without stem cell therapy T Ben-Mordechai, R Holbova, N Landa-Rouben, T Harel-Adar, ... Journal of the American College of Cardiology 62 (20), 1890-1901, 2013 | 289 | 2013 |
Cathepsin B inhibition limits bone metastasis in breast cancer NP Withana, G Blum, M Sameni, C Slaney, A Anbalagan, MB Olive, ... Cancer research 72 (5), 1199-1209, 2012 | 223 | 2012 |
Substrate competitive inhibitors of IGF-1 receptor kinase G Blum, A Gazit, A Levitzki Biochemistry 39 (51), 15705-15712, 2000 | 205 | 2000 |
Functional imaging of legumain in cancer using a new quenched activity-based probe LE Edgington, M Verdoes, A Ortega, NP Withana, J Lee, S Syed, ... Journal of the American Chemical Society 135 (1), 174-182, 2013 | 167 | 2013 |
Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics G Blum, A Gazit, A Levitzki Journal of Biological Chemistry 278 (42), 40442-40454, 2003 | 159 | 2003 |
VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation SH Chang, K Kanasaki, V Gocheva, G Blum, J Harper, MA Moses, ... Cancer research 69 (10), 4537-4544, 2009 | 155 | 2009 |
Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation D Cavallo-Medved, D Rudy, G Blum, M Bogyo, D Caglic, BF Sloane Experimental cell research 315 (7), 1234-1246, 2009 | 135 | 2009 |
Acid-mediated tumor proteolysis: contribution of cysteine cathepsins JM Rothberg, KM Bailey, JW Wojtkowiak, Y Ben-Nun, M Bogyo, E Weber, ... Neoplasia 15 (10), 1125-IN9, 2013 | 122 | 2013 |
Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity G Blum, RM Weimer, LE Edgington, W Adams, M Bogyo PLoS One 4 (7), e6374, 2009 | 119 | 2009 |
A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages M Verdoes, LE Edgington, FA Scheeren, M Leyva, G Blum, K Weiskopf, ... Chemistry & biology 19 (5), 619-628, 2012 | 118 | 2012 |
Macrophage-induced lymphangiogenesis and metastasis following paclitaxel chemotherapy is regulated by VEGFR3 D Alishekevitz, S Gingis-Velitski, O Kaidar-Person, L Gutter-Kapon, ... Cell reports 17 (5), 1344-1356, 2016 | 108 | 2016 |
Kobophenol A inhibits binding of host ACE2 receptor with spike RBD domain of SARS-CoV-2, a lead compound for blocking COVID-19 S Gangadevi, VN Badavath, A Thakur, N Yin, S De Jonghe, O Acevedo, ... The journal of physical chemistry letters 12 (7), 1793-1802, 2021 | 94 | 2021 |
Topical application of activity-based probes for visualization of brain tumor tissue JL Cutter, NT Cohen, J Wang, AE Sloan, AR Cohen, A Panneerselvam, ... PloS one 7 (3), e33060, 2012 | 83 | 2012 |
A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C F Yuan, SHL Verhelst, G Blum, LM Coussens, M Bogyo Journal of the American Chemical Society 128 (17), 5616-5617, 2006 | 79 | 2006 |
Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer H Gibori, S Eliyahu, A Krivitsky, D Ben-Shushan, Y Epshtein, G Tiram, ... Nature communications 9 (1), 16, 2018 | 77 | 2018 |
A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression SJ Salpeter, Y Pozniak, E Merquiol, Y Ben-Nun, T Geiger, G Blum Oncogene 34 (50), 6066-6078, 2015 | 68 | 2015 |