ATG15 encodes a phospholipase and is transcriptionally regulated by YAP1 in Saccharomyces cerevisiae V Ramya, R Rajasekharan FEBS letters 590 (18), 3155-3167, 2016 | 41 | 2016 |
Phosphatidylinositol 5 phosphate 4-kinase regulates plasma-membrane PIP3 turnover and insulin signaling S Sharma, S Mathre, V Ramya, D Shinde, P Raghu Cell reports 27 (7), 1979-1990. e7, 2019 | 30 | 2019 |
Arabidopsis serine/threonine/tyrosine protein kinase phosphorylates oil body proteins that regulate oil content in the seeds I Ramachandiran, A Vijayakumar, V Ramya, R Rajasekharan Scientific Reports 8 (1), 1154, 2018 | 20 | 2018 |
Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes S Mathre, KB Reddy, V Ramya, H Krishnan, A Ghosh, P Raghu Bioscience Reports 39 (2), BSR20182210, 2019 | 13 | 2019 |
A novel mass assay to measure phosphatidylinositol-5-phosphate from cells and tissues A Ghosh, S Sharma, D Shinde, V Ramya, P Raghu Bioscience Reports 39 (10), BSR20192502, 2019 | 11 | 2019 |
A novel fluorogenic reporter substrate for 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-2 (PLCγ2): Application to high-throughput screening for activators … R Visvanathan, T Utsuki, DE Beck, E Lendy, K Sun, Y Liu, KW Hering, ... SLAS Discovery 28 (4), 170-179, 2023 | 1 | 2023 |
Identification of PLCG2 activators for the treatment of Alzheimer’s disease B Clayton, SM Massey, DE Beck, KS Putt, T Utsuki, R Visvanathan, ... Alzheimer's Association International Conference, 2024 | | 2024 |
A novel micellular fluorogenic substrate for quantitating the activity of 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma (PLCγ) enzymes R Visvanathan, T Utsuki, DE Beck, WB Clayton, E Lendy, K Sun, Y Liu, ... Plos one 19 (3), e0299541, 2024 | | 2024 |
A target enablement package for modulating the activity of PLCγ2 as a therapeutic strategy for the treatment of Alzheimer’s disease B Clayton, SJ Bissel, TI Richardson, SM Massey, DE Beck, KS Putt, ... Alzheimer's & Dementia 19, e074712, 2023 | | 2023 |
IUSM-Purdue TREAT-AD Center target enabling component m-3M3FBS analogs evaluated as PLCγ2 chemical probes. ME Clayton WB, Putt KS, Richardson T, Beck D, Massey S, Utsuki T ... AD Knowledge Portal, 2023 | | 2023 |
IUSM-Purdue TREAT-AD center target enabling component establishing a flow scheme to discovery novel PLCγ2 chemical probes. LE Clayton WB, Richardson T, Putt KS, Beck D, Massey S, Utsuki T ... AD Knolwedge Portal., 2023 | | 2023 |
IUSM-Purdue TREAT-AD Center Target Enabling Component: PLCγ2 solution substrate synthesis – C8CFC3. PKS Beck D, Clayton W.B., Massey S, Utsuki T, Visvanathan R, Sun, K-L, Liu ... AD Knowledge Portal., 2022 | | 2022 |
IUSM-Purdue TREAT-AD Center Target Enabling Component: PLCγ2 micelle and liposome substrate synthesis – C16CFC3. PKS Beck D, Clayton W.B., Massey S, Utsuki T, Visvanathan R, Sun, K-L, Liu ... AD Knowledge Portal., 2022 | | 2022 |
IUSM-Purdue TREAT-AD Center Target Enabling Component: PLCγ2 in vitro solution assay using the water soluble C8CF3C substrate. PKS Utsuki T, Visvanathan R, Beck D, Clayton W.B., Massey S, Lendy E, Kaiser ... AD Knowledge Portal., 2022 | | 2022 |
IUSM-Purdue TREAT-AD Center Target Enabling Component: XY-69 liposome substrate preparation and assay optimization for monitoring PLCγ2 enzymatic activity in vitro. PKS Utsuki T, Visvanathan R, Beck D, Clayton W.B., Massey S, Lendy E, Kaiser ... AD Knowledge Portal., 2022 | | 2022 |
IUSM-Purdue TREAT-AD Center Target Enabling Component PLCγ2 In Vitro Micelle Assay Using the Hydrophobic C16CF3-coumarin Substrate. PKS Visvanathan R, Utsuki T, Beck D, Clayton B, Massey S, Lendy E, Kaiser B ... AD Knowledge Portal, 2022 | | 2022 |
Signalling Growth through Lipid Kinases S Sharma, S Mathre, V Ramya, D Shinde, P Raghu Biophysical Journal 116 (3), 130a, 2019 | | 2019 |
Insulin sensitivity and PIP3 turnover in Drosophila are regulated by phosphatidylinositol 5 phosphate 4-kinase S Sharma, S Mathre, R Visvanathan, D Shinde, P Raghu bioRxiv, 333153, 2018 | | 2018 |
Transcriptional regulation of phospholipases by Yeast Activator Protein-1 in Saccharomyces cerevisiae V Ramya AcSIR, 2016 | | 2016 |