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Mechanisms of disease: astrocytes in neurodegenerative disease NJ Maragakis, JD Rothstein Nature clinical practice Neurology 2 (12), 679-689, 2006 | 1063 | 2006 |
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ... Neuron 80 (2), 415-428, 2013 | 1031 | 2013 |
C9orf72 nucleotide repeat structures initiate molecular cascades of disease AR Haeusler, CJ Donnelly, G Periz, EAJ Simko, PG Shaw, MS Kim, ... Nature 507 (7491), 195-200, 2014 | 1021 | 2014 |
Protective role of reactive astrocytes in brain ischemia L Li, A Lundkvist, D Andersson, U Wilhelmsson, N Nagai, AC Pardo, ... Journal of Cerebral Blood Flow & Metabolism 28 (3), 468-481, 2008 | 619 | 2008 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 601 | 2018 |
Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease AC Lepore, B Rauck, C Dejea, AC Pardo, MS Rao, JD Rothstein, ... Nature neuroscience 11 (11), 1294-1301, 2008 | 493 | 2008 |
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ... New England Journal of Medicine 383 (2), 109-119, 2020 | 471 | 2020 |
Glutamate transporters: animal models to neurologic disease NJ Maragakis, JD Rothstein Neurobiology of disease 15 (3), 461-473, 2004 | 440 | 2004 |
Glutamate transporters in neurologic disease NJ Maragakis, JD Rothstein Archives of neurology 58 (3), 365-370, 2001 | 405 | 2001 |
Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury DA Kerr, J Lladó, MJ Shamblott, NJ Maragakis, DN Irani, TO Crawford, ... Journal of Neuroscience 23 (12), 5131-5140, 2003 | 370 | 2003 |
Recovery from paralysis in adult rats using embryonic stem cells DM Deshpande, YS Kim, T Martinez, J Carmen, S Dike, I Shats, LL Rubin, ... Annals of neurology 60 (1), 32-44, 2006 | 343 | 2006 |
Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors J Lladó, C Haenggeli, NJ Maragakis, EY Snyder, JD Rothstein Molecular and Cellular Neuroscience 27 (3), 322-331, 2004 | 287 | 2004 |
Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo ST Papadeas, SE Kraig, C O'Banion, AC Lepore, NJ Maragakis Proceedings of the National Academy of Sciences 108 (43), 17803-17808, 2011 | 254 | 2011 |
Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking FM Laird, MH Farah, S Ackerley, A Hoke, N Maragakis, JD Rothstein, ... Journal of Neuroscience 28 (9), 1997-2005, 2008 | 239 | 2008 |
Mechanisms, models and biomarkers in amyotrophic lateral sclerosis MR Turner, R Bowser, L Bruijn, L Dupuis, A Ludolph, M McGrath, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (sup1), 19-32, 2013 | 212 | 2013 |
Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons RP Irwin, NJ Maragakis, MA Rogawski, RH Purdy, DH Farb, SM Paul Neuroscience letters 141 (1), 30-34, 1992 | 210 | 1992 |
A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus T Ueki, M Tanaka, K Yamashita, S Mikawa, ZF Qiu, NJ Maragakis, ... Journal of Neuroscience 23 (37), 11732-11740, 2003 | 177 | 2003 |
Concordant but varied phenotypes among Duchenne muscular dystrophy patient-specific myoblasts derived using a human iPSC-based model IY Choi, HT Lim, K Estrellas, J Mula, TV Cohen, Y Zhang, CJ Donnelly, ... Cell reports 15 (10), 2301-2312, 2016 | 170 | 2016 |
Altered expression of the glutamate transporter EAAT2b in neurological disease NJ Maragakis, M Dykes‐Hoberg, JD Rothstein Annals of neurology 55 (4), 469-477, 2004 | 170 | 2004 |