Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes … P Taslimi, HE Aslan, Y Demir, N Oztaskin, A Maraş, İ Gulçin, S Beydemir, ... International journal of biological macromolecules 119, 857-863, 2018 | 183 | 2018 |
Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors M Gümüş, ŞN Babacan, Y Demir, Y Sert, İ Koca, İ Gülçin Archiv Der Pharmazie 355 (1), 2100242, 2022 | 178 | 2022 |
Novel 2-aminopyridine liganded Pd (II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties F Erdemir, DB Celepci, A Aktaş, Y Gök, R Kaya, P Taslimi, Y Demir, ... Bioorganic chemistry 91, 103134, 2019 | 151 | 2019 |
The effects of hesperidin on sodium arsenite‐induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach C Caglayan, Y Demir, S Kucukler, P Taslimi, FM Kandemir, İ Gulçin Journal of food biochemistry 43 (2), e12720, 2019 | 135 | 2019 |
Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors C Türkeş, M Arslan, Y Demir, L Cocaj, AR Nixha, Ş Beydemir Bioorganic chemistry 89, 103004, 2019 | 132 | 2019 |
The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide‐induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activities P Taslimi, FM Kandemir, Y Demir, M İleritürk, Y Temel, C Caglayan, ... Journal of biochemical and molecular toxicology 33 (6), e22313, 2019 | 122 | 2019 |
Antidiabetic properties of dietary phenolic compounds: Inhibition effects on α‐amylase, aldose reductase, and α‐glycosidase Y Demir, L Durmaz, P Taslimi, İ Gulçin Biotechnology and applied biochemistry 66 (5), 781-786, 2019 | 100 | 2019 |
Antidiabetic potential: In vitro inhibition effects of bromophenol and diarylmethanones derivatives on metabolic enzymes Y Demir, P Taslimi, MS Ozaslan, N Oztaskin, Y Çetinkaya, İ Gulçin, ... Archiv der pharmazie 351 (12), 1800263, 2018 | 95 | 2018 |
Naphthoquinones, benzoquinones, and anthraquinones: Molecular docking, ADME and inhibition studies on human serum paraoxonase‐1 associated with cardiovascular diseases Y Demir Drug development research 81 (5), 628-636, 2020 | 89 | 2020 |
Changes in the anti-oxidant system in adult epilepsy patients receiving anti-epileptic drugs M Işık, Y Demir, M Kırıcı, R Demir, F Şimşek, Ş Beydemir Archives of physiology and biochemistry 121 (3), 97-102, 2015 | 89 | 2015 |
Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo [2, 1-b][1, 3, 4] thiadiazoles as highly potent acetylcholinesterase and non-classical … S Askin, H Tahtaci, C Türkeş, Y Demir, A Ece, GA Çiftçi, Ş Beydemir Bioorganic Chemistry 113, 105009, 2021 | 88 | 2021 |
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases M Durgun, C Türkeş, M Işık, Y Demir, A Saklı, A Kuru, A Güzel, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 950-962, 2020 | 88 | 2020 |
Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney Y Demir, M Işık, İ Gülçin, Ş Beydemir Journal of biochemical and molecular toxicology 31 (9), e21936, 2017 | 84 | 2017 |
Synthesis and inhibition profiles of N-benzyl-and N-allyl aniline derivatives against carbonic anhydrase and acetylcholinesterase–A molecular docking study I Mahmudov, Y Demir, Y Sert, Y Abdullayev, A Sujayev, SH Alwasel, ... Arabian Journal of Chemistry 15 (3), 103645, 2022 | 83 | 2022 |
Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors B Sever, C Türkeş, MD Altıntop, Y Demir, Ş Beydemir International Journal of Biological Macromolecules 163, 1970-1988, 2020 | 81 | 2020 |
Anti-diabetic properties of calcium channel blockers: inhibition effects on aldose reductase enzyme activity C Türkeş, Y Demir, Ş Beydemir Applied biochemistry and biotechnology 189, 318-329, 2019 | 80 | 2019 |
Inhibition effects of some pesticides and heavy metals on carbonic anhydrase enzyme activity purified from horse mackerel (Trachurus trachurus) gill tissues C Caglayan, P Taslimi, C Türk, İ Gulcin, FM Kandemir, Y Demir, ... Environmental Science and Pollution Research 27, 10607-10616, 2020 | 78 | 2020 |
The behaviour of some antihypertension drugs on human serum paraoxonase-1: an important protector enzyme against atherosclerosis Y Demir Journal of pharmacy and pharmacology 71 (10), 1576-1583, 2019 | 78 | 2019 |
Calcium channel blockers: molecular docking and inhibition studies on carbonic anhydrase I and II isoenzymes C Türkeş, Y Demir, Ş Beydemir Journal of Biomolecular Structure and Dynamics 39 (5), 1672-1680, 2021 | 76 | 2021 |
The effects of zingerone against vancomycin‐induced lung, liver, kidney and testis toxicity in rats: The behavior of some metabolic enzymes C Çağlayan, P Taslimi, Y Demir, S Küçükler, FM Kandemir, İ Gulçin Journal of biochemical and molecular toxicology 33 (10), e22381, 2019 | 74 | 2019 |