Bioorthogonal PROTAC prodrugs enabled by on-target activation M Chang, F Gao, D Pontigon, G Gnawali, H Xu, W Wang Journal of the American Chemical Society 145 (25), 14155-14163, 2023 | 51 | 2023 |
Metabonomics reveals that triclocarban affects liver metabolism by affecting glucose metabolism, β-oxidation of fatty acids, and the TCA cycle in male mice W Li, W Zhang, M Chang, J Ren, W Xie, H Chen, Z Zhang, X Zhuang, ... Toxicology Letters 299, 76-85, 2018 | 39 | 2018 |
Building bioorthogonal click-release capable artificial receptors on cancer cell surface for imaging, drug targeting and delivery J Chen, P Ji, G Gnawali, M Chang, F Gao, H Xu, W Wang Acta Pharmaceutica Sinica B 13 (6), 2736-2746, 2023 | 16 | 2023 |
MDM2-BCL-XL PROTACs enable degradation of BCL-XL and stabilization of p53 M Chang, F Gao, J Chen, G Gnawali, W Wang Acta materia medica 1 (3), 333, 2022 | 13 | 2022 |
Senolysis Enabled by Senescent Cell‐Sensitive Bioorthogonal Tetrazine Ligation M Chang, Y Dong, H Xu, AB Cruickshank‐Taylor, JS Kozora, B Behpour, ... Angewandte Chemie International Edition 63 (9), e202315425, 2024 | 11 | 2024 |
Quadrupole orbitrap mass spectrometer-based metabonomic elucidation of influences of short-term di (2-ethylhexyl) phthalate exposure on cardiac metabolism in male mice W Li, W Zhang, M Chang, J Ren, X Zhuang, Z Zhang, Y Cui, H Chen, B Xu, ... Chemical Research in Toxicology 31 (11), 1185-1194, 2018 | 8 | 2018 |
Photoredox Catalytic Installation of an Alkyl/Aryl Side Chain and Deuterium into (S)-Methyleneoxazolidinone: Synthesis of Enantioenriched α-Deuterated α-Amino … Y Dong, X Meng, G Gnawali, M Chang, W Wang Organic Letters 25 (25), 4745-4749, 2023 | 7 | 2023 |
Selective Elimination of Senescent Cancer Cells by Galacto-Modified PROTACs M Chang, F Gao, G Gnawali, H Xu, Y Dong, X Meng, W Li, Z Wang, ... Journal of Medicinal Chemistry 67 (9), 7301-7311, 2024 | 6 | 2024 |
Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib ST Nawrocki, CM Espitia, MJC Espinoza, TM Jones, ME Gamble, ... Clinical and Translational Medicine 14 (4), 2024 | 2 | 2024 |
Senolytic Prodrugs: A Promising Approach to Enhancing Senescence‐Targeting Intervention M Chang, Y Dong, AB Cruickshank‐Taylor, G Gnawali, F Bi, W Wang Chembiochem 25 (22), e202400355, 2024 | 1 | 2024 |
Control of tetrazine bioorthogonal reactivity by naphthotube and phenyltetrazine host-guest pairs K Lou, W Xing, X Meng, M Chang, W Wang Chem 9 (10), 2727-2730, 2023 | 1 | 2023 |
Dual-Performing Vinyltetrazine for Rapid, Selective Bioconjugation and Functionalization of Cysteine Proteins M Chang, H Xu, Y Dong, G Gnawali, F Bi, W Wang ACS chemical biology, 2024 | | 2024 |
Targeting autophagy: A promising approach for the treatment of breast cancer brain metastases ST Nawrocki, CM Espitia, MJC Espinoza, ME Gamble, S Sureshkumar, ... Clinical and Translational Discovery 4 (4), e340, 2024 | | 2024 |
Site-Selective Modification of Secondary Amine Moieties on Native Peptides, Proteins, and Natural Products with Ynones F Gao, M Chang, X Meng, H Xu, G Gnawali, Y Dong, B Lopez, W Wang Bioconjugate Chemistry 34 (9), 1553-1562, 2023 | | 2023 |