| Recent advances in the synthesis of biologically active spirooxindoles MMM Santos Tetrahedron 70 (52), 9735-9757, 2014 | 400 | 2014 |
| Michael acceptors as cysteine protease inhibitors. MM Santos, R Moreira Mini reviews in medicinal chemistry 7 (10), 1040-1050, 2007 | 191 | 2007 |
| Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho [2, 3-d] isoxazole-4, 9-diones MMM Santos, N Faria, J Iley, SJ Coles, MB Hursthouse, ML Martins, ... Bioorganic & medicinal chemistry letters 20 (1), 193-195, 2010 | 139 | 2010 |
| Synthesis of novel spiropyrazoline oxindoles and evaluation of cytotoxicity in cancer cell lines  Monteiro, LM Gonçalves, MMM Santos European Journal of Medicinal Chemistry 79, 266-272, 2014 | 101 | 2014 |
| Straightforward Methodology for the Enantioselective Synthesis of Benzo[a]- and Indolo[2,3-a]quinolizidines M Amat, MMM Santos, O Bassas, N Llor, C Escolano, A Gómez-Esqué, ... The Journal of Organic Chemistry 72 (14), 5193-5201, 2007 | 75 | 2007 |
| Enhancing macrocyclic diterpenes as multidrug-resistance reversers: structure–activity studies on jolkinol D derivatives M Reis, RJ Ferreira, MMM Santos, DJVA dos Santos, J Molnár, ... Journal of Medicinal Chemistry 56 (3), 748-760, 2013 | 74 | 2013 |
| Synthesis and evaluation of spiroisoxazoline oxindoles as anticancer agents CJA Ribeiro, JD Amaral, CMP Rodrigues, R Moreira, MMM Santos Bioorganic & medicinal chemistry 22 (1), 577-584, 2014 | 68 | 2014 |
| Antidepressant-like and antinociceptive-like actions of 4-(4′-chlorophenyl)-6-(4 ″-methylphenyl)-2-hydrazinepyrimidine Mannich base in mice ALS Rodrigues, JM Rosa, VM Gadotti, EC Goulart, MM Santos, AV Silva, ... Pharmacology Biochemistry and Behavior 82 (1), 156-162, 2005 | 66 | 2005 |
| Enantioselective formal synthesis of (+)-dihydrocorynantheine and (−)-dihydrocorynantheol M Amat, A Gómez-Esqué, C Escolano, MMM Santos, E Molins, J Bosch The Journal of Organic Chemistry 74 (3), 1205-1211, 2009 | 56 | 2009 |
| Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53–MDM2 interaction J Soares, NAL Pereira, Â Monteiro, M Leao, C Bessa, DJVA Dos Santos, ... European Journal of Pharmaceutical Sciences 66, 138-147, 2015 | 53 | 2015 |
| Enantioselective spirocyclizations from tryptophanol-derived oxazolopiperidone lactams M Amat, MMM Santos, AM Gómez, D Jokic, E Molins, J Bosch Organic Letters 9 (15), 2907-2910, 2007 | 51 | 2007 |
| An update on MDMX and dual MDM2/X inhibitors M Espadinha, V Barcherini, EA Lopes, MMM Santos Current topics in medicinal chemistry 18 (8), 647-660, 2018 | 50 | 2018 |
| Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline M Amat, C Ramos, M Pérez, E Molins, P Florindo, MMM Santos, J Bosch Chemical Communications 49 (19), 1954-1956, 2013 | 50 | 2013 |
| A tryptophanol-derived oxazolopiperidone lactam is cytotoxic against tumors via inhibition of p53 interaction with murine double minute proteins J Soares, L Raimundo, NAL Pereira, DJVA dos Santos, M Pérez, ... Pharmacological Research 95, 42-52, 2015 | 49 | 2015 |
| DIMP 53‐1: a novel small‐molecule dual inhibitor of p53–MDM 2/X interactions with multifunctional p53‐dependent anticancer properties J Soares, M Espadinha, L Raimundo, H Ramos, AS Gomes, S Gomes, ... Molecular Oncology 11 (6), 612-627, 2017 | 48 | 2017 |
| Chemical variations on the p53 reactivation theme CJA Ribeiro, CMP Rodrigues, R Moreira, MMM Santos Pharmaceuticals 9 (2), 25, 2016 | 46 | 2016 |
| Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule J Soares, L Raimundo, NAL Pereira, Â Monteiro, S Gomes, C Bessa, ... Oncotarget 7 (4), 4326, 2016 | 46 | 2016 |
| Squaric acid: a valuable scaffold for developing antimalarials? SP Kumar, PMC Glória, LM Gonçalves, J Gut, PJ Rosenthal, R Moreira, ... MedChemComm 3 (4), 489-493, 2012 | 45 | 2012 |
| Design, synthesis and evaluation of 3-methylene-substituted indolinones as antimalarials SP Kumar, J Gut, RC Guedes, PJ Rosenthal, MMM Santos, R Moreira European journal of medicinal chemistry 46 (3), 927-933, 2011 | 45 | 2011 |
| Biogenetically Inspired Enantioselective Approach to Indolo[2,3-a]- and Benzo[a]quinolizidine Alkaloids from a Synthetic Equivalent of Secologanin O Bassas, N Llor, MMM Santos, R Griera, E Molins, M Amat, J Bosch Organic Letters 7 (14), 2817-2820, 2005 | 42 | 2005 |
Milton de Arruda MartinsProfessor of Medicine, School of Medicine, University of Sao Paulo, Brazil在 usp.br 的电子邮件经过验证
Milton de Arruda MartinsProfessor of Medicine, School of Medicine, University of Sao Paulo, Brazil在 usp.br 的电子邮件经过验证