Microglial phagocytosis of neurons in neurodegeneration, and its regulation CA Butler, AS Popescu, EJA Kitchener, DH Allendorf, M Puigdellívol, ... Journal of neurochemistry 158 (3), 621-639, 2021 | 171 | 2021 |
Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity A Giralt, M Puigdellivol, O Carretón, P Paoletti, J Valero, A Parra-Damas, ... Human molecular genetics 21 (6), 1203-1216, 2012 | 165 | 2012 |
Neurotrophin receptor p75NTR mediates Huntington’s disease–associated synaptic and memory dysfunction V Brito, A Giralt, L Enriquez-Barreto, M Puigdellívol, N Suelves, ... The Journal of clinical investigation 124 (10), 4411-4428, 2014 | 107 | 2014 |
Imbalance of p75NTR/TrkB protein expression in Huntington’s disease: implication for neuroprotective therapies V Brito, M Puigdellívol, A Giralt, D del Toro, J Alberch, S Ginés Cell death & disease 4 (4), e595-e595, 2013 | 99 | 2013 |
Sialylation and galectin-3 in microglia-mediated neuroinflammation and neurodegeneration M Puigdellívol, DH Allendorf, GC Brown Frontiers in cellular neuroscience 14, 162, 2020 | 91 | 2020 |
Singular location and signaling profile of adenosine A2A-cannabinoid CB1 receptor heteromers in the dorsal striatum E Moreno, A Chiarlone, M Medrano, M Puigdellívol, L Bibic, LA Howell, ... Neuropsychopharmacology 43 (5), 964-977, 2018 | 74 | 2018 |
Activated microglia desialylate their surface, stimulating complement receptor 3‐mediated phagocytosis of neurons DH Allendorf, M Puigdellívol, GC Brown Glia 68 (5), 989-998, 2020 | 59 | 2020 |
A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease M Puigdellívol, M Cherubini, V Brito, A Giralt, N Suelves, J Ballesteros, ... Human Molecular Genetics 24 (25), 7265-7285, 2015 | 46 | 2015 |
The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration M Puigdellívol, S Milde, A Vilalta, TOJ Cockram, DH Allendorf, JY Lee, ... Cell Reports 37 (13), 2021 | 44 | 2021 |
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, ... Journal of Biological Chemistry 296, 2021 | 41 | 2021 |
Cdk5-mediated mitochondrial fission: a key player in dopaminergic toxicity in Huntington's disease M Cherubini, M Puigdellívol, J Alberch, S Ginés Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (10 …, 2015 | 40 | 2015 |
Calreticulin and galectin-3 opsonise bacteria for phagocytosis by microglia TOJ Cockram, M Puigdellívol, GC Brown Frontiers in immunology 10, 2647, 2019 | 36 | 2019 |
BDNF induces striatal-enriched protein tyrosine phosphatase 61 degradation through the proteasome A Saavedra, M Puigdellívol, S Tyebji, P Kurup, J Xu, S Ginés, J Alberch, ... Molecular neurobiology 53, 4261-4273, 2016 | 32 | 2016 |
Inflammatory neuronal loss in the substantia nigra induced by systemic lipopolysaccharide is prevented by knockout of the P2Y6 receptor in mice S Milde, FW van Tartwijk, A Vilalta, TC Hornik, JM Dundee, M Puigdellívol, ... Journal of neuroinflammation 18, 1-9, 2021 | 31 | 2021 |
Cognitive dysfunction in H untington's disease: mechanisms and therapeutic strategies beyond BDNF M Puigdellívol, A Saavedra, E Pérez‐Navarro Brain Pathology 26 (6), 752-771, 2016 | 31 | 2016 |
Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease D Moreno-Delgado, M Puigdellívol, E Moreno, M Rodríguez-Ruiz, J Botta, ... Elife 9, e51093, 2020 | 25 | 2020 |
Cdk5 contributes to Huntington’s disease learning and memory deficits via modulation of brain region-specific substrates E Alvarez-Periel, M Puigdellívol, V Brito, F Plattner, JA Bibb, J Alberch, ... Molecular neurobiology 55, 6250-6268, 2018 | 25 | 2018 |
Effective knockdown of gene expression in primary microglia with siRNA and magnetic nanoparticles without cell death or inflammation A Carrillo-Jimenez, M Puigdellívol, A Vilalta, JL Venero, GC Brown, ... Frontiers in cellular neuroscience 12, 313, 2018 | 24 | 2018 |
P2Y6 receptor‐dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging JM Dundee, M Puigdellívol, R Butler, TOJ Cockram, GC Brown Aging Cell 22 (2), e13761, 2023 | 15 | 2023 |
Chelerythrine promotes Ca2+-dependent calpain activation in neuronal cells in a PKC-independent manner A Saavedra, S Fernández-García, S Cases, M Puigdellívol, R Alcalá-Vida, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 922-935, 2017 | 14 | 2017 |