Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells K Si‐Tayeb, FK Noto, M Nagaoka, J Li, MA Battle, C Duris, PE North, ... Hepatology 51 (1), 297-305, 2010 | 1451 | 2010 |
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. JD Molkentin, Q Lin, SA Duncan, EN Olson Genes & development 11 (8), 1061-1072, 1997 | 1440 | 1997 |
Organogenesis and development of the liver K Si-Tayeb, FP Lemaigre, SA Duncan Developmental cell 18 (2), 175-189, 2010 | 942 | 2010 |
Mammalian hepatocyte differentiation requires the transcription factor HNF-4α J Li, G Ning, SA Duncan Genes & development 14 (4), 464-474, 2000 | 759 | 2000 |
Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis F Parviz, C Matullo, WD Garrison, L Savatski, JW Adamson, G Ning, ... Nature genetics 34 (3), 292-296, 2003 | 722 | 2003 |
Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. WS Chen, K Manova, DC Weinstein, SA Duncan, AS Plump, VR Prezioso, ... Genes & development 8 (20), 2466-2477, 1994 | 685 | 1994 |
The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4 RG Tirona, W Lee, BF Leake, LB Lan, CB Cline, V Lamba, F Parviz, ... Nature medicine 9 (2), 220-224, 2003 | 551 | 2003 |
The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism M Stoffel, SA Duncan Proceedings of the National Academy of Sciences 94 (24), 13209-13214, 1997 | 515 | 1997 |
Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability T Oka, M Maillet, AJ Watt, RJ Schwartz, BJ Aronow, SA Duncan, ... Circulation research 98 (6), 837-845, 2006 | 482 | 2006 |
Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in … SA Duncan, K Manova, WS Chen, P Hoodless, DC Weinstein, ... Proceedings of the National Academy of Sciences 91 (16), 7598-7602, 1994 | 450 | 1994 |
Regulation of a transcription factor network required for differentiation and metabolism SA Duncan, MA Navas, D Dufort, J Rossant, M Stoffel Science 281 (5377), 692-695, 1998 | 440 | 1998 |
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis AJ Watt, MA Battle, J Li, SA Duncan Proceedings of the National Academy of Sciences 101 (34), 12573-12578, 2004 | 422 | 2004 |
Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2 S Signorini, YJ Liao, SA Duncan, LY Jan, M Stoffel Proceedings of the National Academy of Sciences 94 (3), 923-927, 1997 | 400 | 1997 |
ER stress controls iron metabolism through induction of hepcidin C Vecchi, G Montosi, K Zhang, I Lamberti, SA Duncan, RJ Kaufman, ... Science 325 (5942), 877-880, 2009 | 390 | 2009 |
Embryonic development of the liver R Zhao, SA Duncan Hepatology 41 (5), 956-967, 2005 | 384 | 2005 |
Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4−/− embryos SA Duncan, A Nagy, W Chan Development 124 (2), 279-287, 1997 | 381 | 1997 |
HNF4: a central regulator of hepatocyte differentiation and function AJ Watt, WD Garrison, SA Duncan Hepatology 37 (6), 1249-1253, 2003 | 365 | 2003 |
Identification of small molecules for human hepatocyte expansion and iPS differentiation J Shan, RE Schwartz, NT Ross, DJ Logan, D Thomas, SA Duncan, ... Nature chemical biology 9 (8), 514-520, 2013 | 316 | 2013 |
Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver MA Battle, G Konopka, F Parviz, AL Gaggl, C Yang, FM Sladek, ... Proceedings of the National Academy of Sciences 103 (22), 8419-8424, 2006 | 313 | 2006 |
The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion RK Gupta, MZ Vatamaniuk, CS Lee, RC Flaschen, JT Fulmer, ... The Journal of clinical investigation 115 (4), 1006-1015, 2005 | 303 | 2005 |