NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential OV Evgenov, P Pacher, PM Schmidt, G Haskó, HHHW Schmidt, JP Stasch Nature reviews Drug discovery 5 (9), 755-768, 2006 | 911 | 2006 |
Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels JP Stasch, PM Schmidt, PI Nedvetsky, TY Nedvetskaya, AK HS, S Meurer, ... The Journal of clinical investigation 116 (9), 2552-2561, 2006 | 524 | 2006 |
The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells E Eljaschewitsch, A Witting, C Mawrin, T Lee, PM Schmidt, S Wolf, ... Neuron 49 (1), 67-79, 2006 | 516 | 2006 |
NO‐and haem‐independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle JP Stasch, P Schmidt, C Alonso‐Alija, H Apeler, K Dembowsky, M Haerter, ... British journal of pharmacology 136 (5), 773-783, 2002 | 397 | 2002 |
Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclase PM Schmidt, M Schramm, H Schröder, F Wunder, JP Stasch Journal of Biological Chemistry 279 (4), 3025-3032, 2004 | 206 | 2004 |
NO-and haem-independent soluble guanylate cyclase activators HHHW Schmidt, PM Schmidt, JP Stasch cGMP: Generators, Effectors and Therapeutic Implications, 309-339, 2009 | 187 | 2009 |
Nitric Oxide–Independent Vasodilator Rescues Heme-Oxidized Soluble Guanylate Cyclase From Proteasomal Degradation S Meurer, S Pioch, T Pabst, N Opitz, PM Schmidt, T Beckhaus, K Wagner, ... Circulation research 105 (1), 33-41, 2009 | 123 | 2009 |
Mechanisms of nitric oxide independent activation of soluble guanylyl cyclase P Schmidt, M Schramm, H Schröder, JP Stasch European journal of pharmacology 468 (3), 167-174, 2003 | 120 | 2003 |
Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation‐induced degradation LS Hoffmann, PM Schmidt, Y Keim, S Schaefer, HHHW Schmidt, ... British journal of pharmacology 157 (5), 781-795, 2009 | 84 | 2009 |
Detection of activity of telomerase in tumor cells using fiber optical biosensors PM Schmidt, C Lehmann, E Matthes, FF Bier Biosensors and Bioelectronics 17 (11-12), 1081-1087, 2002 | 84 | 2002 |
NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272 EM Becker, C Alonso-Alija, H Apeler, R Gerzer, T Minuth, U Pleiβ, ... BMC pharmacology 1, 1-12, 2001 | 80 | 2001 |
Microgravity-induced alterations in signal transduction in cells of the immune system K Paulsen, C Thiel, J Timm, PM Schmidt, K Huber, S Tauber, ... Acta Astronautica 67 (9-10), 1116-1125, 2010 | 69 | 2010 |
Identification and localization of connexin26 within the photoreceptor-horizontal cell synaptic complex U Janssen-Bienhold, K Schultz, A Gellhaus, P Schmidt, J Ammermueller, ... Visua; Neuroscience 18, 169-178, 2001 | 63 | 2001 |
Tumour stage distribution and survival of malignant melanoma in Germany 2002–2011 O Schoffer, S Schülein, G Arand, H Arnholdt, D Baaske, RC Bargou, ... BMC cancer 16, 1-12, 2016 | 55 | 2016 |
A generic system for the expression and purification of soluble and stable influenza neuraminidase PM Schmidt, RM Attwood, PG Mohr, SA Barrett, JL McKimm-Breschkin PloS one 6 (2), e16284, 2011 | 55 | 2011 |
Identification of residues crucially involved in soluble guanylate cyclase activation C Rothkegel, PM Schmidt, F Stoll, H Schröder, HHHW Schmidt, JP Stasch FEBS letters 580 (17), 4205-4213, 2006 | 48 | 2006 |
Residues stabilizing the heme moiety of the nitric oxide sensor soluble guanylate cyclase PM Schmidt, C Rothkegel, F Wunder, H Schröder, JP Stasch European journal of pharmacology 513 (1-2), 67-74, 2005 | 48 | 2005 |
Cellular distribution of the mRNA for the κ-opioid receptor in the human neocortex: a non-isotopic in situ hybridization study A Wevers, P Schmidt, E Cserpan, I Cserpan, K Maderspach, M Staak, ... Neuroscience letters 195 (2), 125-128, 1995 | 46 | 1995 |
Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses S Barrett, PG Mohr, PM Schmidt, JL McKimm-Breschkin PLoS One 6 (8), e23627, 2011 | 45 | 2011 |
Oligonucleotide microarray for identification of Bacillus anthracis based on intergenic transcribed spacers in ribosomal DNA U Nübel, PM Schmidt, E Reiß, F Bier, W Beyer, D Naumann FEMS microbiology letters 240 (2), 215-223, 2004 | 44 | 2004 |