A self-sufficient cytochrome P450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox center GA Roberts, A Celik, DJB Hunter, TWB Ost, JH White, SK Chapman, ... Journal of Biological Chemistry 278 (49), 48914-48920, 2003 | 146 | 2003 |
Microneedles in drug delivery: progress and challenges M Avcil, A Çelik Micromachines 12 (11), 1321, 2021 | 108 | 2021 |
The olive mill wastewater as substrate for single cell oil production by Zygomycetes S Bellou, A Makri, D Sarris, K Michos, P Rentoumi, A Celik, ... Journal of Biotechnology 170, 50-59, 2014 | 81 | 2014 |
Efficient terpene hydroxylation catalysts based upon P450 enzymes derived from actinomycetes A Çelik, SL Flitsch, NJ Turner Organic & biomolecular chemistry 3 (16), 2930-2934, 2005 | 54 | 2005 |
Biochemical characterization of a novel glucose isomerase from Anoxybacillus gonensis G2T that displays a high level of activity and thermal stability H Karaoglu, D Yanmis, FA Sal, A Celik, S Canakci, AO Belduz Journal of Molecular Catalysis B: Enzymatic 97, 215-224, 2013 | 53 | 2013 |
An unusually cold active nitroreductase for prodrug activations A Çelik, G Yetiş Bioorganic & medicinal chemistry 20 (11), 3540-3550, 2012 | 52 | 2012 |
Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical study M Avcil, G Akman, J Klokkers, D Jeong, A Çelik Journal of Cosmetic Dermatology 19 (2), 328-337, 2020 | 40 | 2020 |
Selective oxidation and reduction reactions with cofactor regeneration mediated by galactitol-, lactate-, and formate dehydrogenases immobilized on magnetic nanoparticles AS Demir, FN Talpur, SB Sopaci, GW Kohring, A Celik Journal of biotechnology 152 (4), 176-183, 2011 | 40 | 2011 |
Enantioselective epoxidation of linolenic acid catalysed by cytochrome P450 BM3 from Bacillus megaterium A Çelik, D Sperandio, RE Speight, NJ Turner Organic & Biomolecular Chemistry 3 (15), 2688-2690, 2005 | 40 | 2005 |
Biological evaluation and molecular docking studies of nitro benzamide derivatives with respect to in vitro anti-inflammatory activity TB Tumer, FC Onder, H Ipek, T Gungor, S Savranoglu, TT Tok, A Celik, ... International immunopharmacology 43, 129-139, 2017 | 35 | 2017 |
Highly stable and reusable immobilized formate dehydrogenases: Promising biocatalysts for in situ regeneration of NADH B Binay, D Alagöz, D Yildirim, A Çelik, SS Tükel Beilstein journal of organic chemistry 12 (1), 271-277, 2016 | 34 | 2016 |
Covalent immobilization of Candida methylica formate dehydrogenase on short spacer arm aldehyde group containing supports D Alagöz, A Çelik, D Yildirim, SS Tükel, B Binay Journal of Molecular Catalysis B: Enzymatic 130, 40-47, 2016 | 32 | 2016 |
Identification of broad specificity P450 CAM variants by primary screening against indole as substrate A Çelik, RE Speight, NJ Turner Chemical communications, 3652-3654, 2005 | 32 | 2005 |
Engineering the active site of ascorbate peroxidase A Çelik, PM Cullis, MJ Sutcliffe, R Sangar, EL Raven European Journal of Biochemistry 268 (1), 78-85, 2001 | 32 | 2001 |
Antiproliferative activity of Humulus lupulus extracts on human hepatoma (Hep3B), colon (HT-29) cancer cells and proteases, tyrosinase, β-lactamase enzyme … F Cömert Önder, M Ay, S Aydoğan Türkoğlu, F Tura Köçkar, A Celik Journal of enzyme inhibition and medicinal chemistry 31 (1), 90-98, 2016 | 28 | 2016 |
Prodrugs for nitroreductase based cancer therapy-2: Novel amide/Ntr combinations targeting PC3 cancer cells T Güngör, FC Önder, E Tokay, ÜG Gülhan, N Hacıoğlu, TT Tok, A Çelik, ... European Journal of Medicinal Chemistry 171, 383-400, 2019 | 24 | 2019 |
Substrate-controlled diastereoselective aziridination of alkenes using 3-acetoxyaminoquinazolinone in the presence of hexamethyldisilazane S Ulukanli, S Karabuga, A Celik, C Kazaz Tetrahedron letters 46 (2), 197-199, 2005 | 24 | 2005 |
Probing the substrate specificity of the catalytically self-sufficient cytochrome P450 RhF from a Rhodococcus sp. A Çelik, GA Roberts, JH White, SK Chapman, NJ Turner, SL Flitsch Chemical communications, 4492-4494, 2006 | 23 | 2006 |
Catalytic oxidation of p-cresol by ascorbate peroxidase A Celik, PM Cullis, EL Raven Archives of Biochemistry and Biophysics 373 (1), 175-181, 2000 | 23 | 2000 |
Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in … E Tokay, T Güngör, N Hacıoğlu, FC Önder, ÜG Gülhan, TT Tok, A Çelik, ... European Journal of Medicinal Chemistry 187, 111937, 2020 | 17 | 2020 |