| Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity G Álvarez, B Aguirre-López, J Varela, M Cabrera, A Merlino, GV López, ... European journal of medicinal chemistry 45 (12), 5767-5772, 2010 | 72 | 2010 |
| 5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene A Gerpe, G Álvarez, D Benítez, L Boiani, M Quiroga, P Hernández, ... Bioorganic & medicinal chemistry 17 (21), 7500-7509, 2009 | 70 | 2009 |
| Identification of a new amide-containing thiazole as a drug candidate for treatment of Chagas' disease G Álvarez, J Varela, E Cruces, M Fernández, M Gabay, SM Leal, ... Antimicrobial agents and chemotherapy 59 (3), 1398-1404, 2015 | 55 | 2015 |
| Potent and selective inhibitors of Trypanosoma cruzi triosephosphate isomerase with concomitant inhibition of cruzipain: Inhibition of parasite growth through multitarget activity E Aguilera, J Varela, E Birriel, E Serna, S Torres, G Yaluff, NV de Bilbao, ... ChemMedChem 11 (12), 1328-1338, 2016 | 50 | 2016 |
| Evaluating 5-nitrofurans as trypanocidal agents C Bot, BS Hall, G Álvarez, R Di Maio, M González, H Cerecetto, ... Antimicrobial agents and chemotherapy 57 (4), 1638-1647, 2013 | 49 | 2013 |
| Optimization of antitrypanosomatid agents: identification of nonmutagenic drug candidates with in vivo activity G Álvarez, J Varela, P Márquez, M Gabay, CE Arias Rivas, K Cuchilla, ... Journal of medicinal chemistry 57 (10), 3984-3999, 2014 | 46 | 2014 |
| Molecular docking and molecular dynamics simulation studies of Trypanosoma cruzi triosephosphate isomerase inhibitors. Insights into the inhibition mechanism and selectivity L Minini, G Álvarez, M González, H Cerecetto, A Merlino Journal of Molecular Graphics and Modelling 58, 40-49, 2015 | 44 | 2015 |
| Caenorhabditis elegans Infrared-Based Motility Assay Identified New Hits for Nematicide Drug Development G Risi, E Aguilera, E Ladós, G Suárez, I Carrera, G Álvarez, G Salinas Veterinary sciences 6 (1), 29, 2019 | 43 | 2019 |
| Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo G Álvarez, J Martínez, J Varela, E Birriel, E Cruces, M Gabay, SM Leal, ... European journal of medicinal chemistry 100, 246-256, 2015 | 43 | 2015 |
| Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp. G Álvarez, C Perdomo, C Coronel, E Aguilera, J Varela, G Aparicio, ... Molecules 22 (5), 709, 2017 | 27 | 2017 |
| New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors: a deeper insight into the mechanism of inhibition G Alvarez, J Martínez, B Aguirre-Lopez, N Cabrera, L Pérez-Díaz, ... Journal of enzyme inhibition and medicinal chemistry 29 (2), 198-204, 2014 | 27 | 2014 |
| Trypanosoma cruzi chemical proteomics using immobilized benznidazole A Trochine, G Alvarez, S Corre, P Faral-Tello, R Durán, CI Batthyany, ... Experimental parasitology 140, 33-38, 2014 | 23 | 2014 |
| Isolation and structural characterization of bioactive molecules on prostate cancer from Mayan traditional medicinal plants RS Fort, JM Trinidad Barnech, J Dourron, M Colazzo, FJ Aguirre-Crespo, ... Pharmaceuticals 11 (3), 78, 2018 | 22 | 2018 |
| Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment E Aguilera, J Varela, E Serna, S Torres, G Yaluff, NV Bilbao, H Cerecetto, ... Memorias do Instituto Oswaldo Cruz 113, 153-160, 2018 | 20 | 2018 |
| 1, 2, 4-thiadiazol-5 (4 H)-ones: a new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibition G Alvarez, B Aguirre-López, N Cabrera, EB Marins, L Tinoco, ... Journal of enzyme inhibition and medicinal chemistry 28 (5), 981-989, 2013 | 20 | 2013 |
| Novel and Selective Rhipicephalus microplus Triosephosphate Isomerase Inhibitors with Acaricidal Activity L Saramago, H Gomes, E Aguilera, H Cerecetto, M González, M Cabrera, ... Veterinary sciences 5 (3), 74, 2018 | 18 | 2018 |
| Synthesis and in vivo proof of concept of a BODIPY-based fluorescent probe as a tracer for biodistribution studies of a new anti-Chagas agent G Rodríguez, J Nargoli, A López, G Moyna, G Álvarez, M Fernández, ... RSC Advances 7 (13), 7983-7989, 2017 | 18 | 2017 |
| 3-H-[1,2]Dithiole as a New Anti-Trypanosoma cruzi Chemotype: Biological and Mechanism of Action Studies M Couto, C Sánchez, B Dávila, V Machín, J Varela, G Álvarez, M Cabrera, ... Molecules 20 (8), 14595-14610, 2015 | 16 | 2015 |
| Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity F Ferraro, I Corvo, L Bergalli, A Ilarraz, M Cabrera, J Gil, BM Susuki, ... Scientific Reports 10 (2587), 2020 | 15 | 2020 |
| Polypharmacology in the treatment of chagas disease E Aguilera, G Alvarez, H Cerecetto, M González Current medicinal chemistry 26 (23), 4476-4489, 2019 | 15 | 2019 |
Sandra Milena Leal PintoProfesor investigador, Universidad de Santander-Colombia在 mail.udes.edu.co 的电子邮件经过验证
