| Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA … WM Eldehna, H Almahli, GH Al-Ansary, HA Ghabbour, MH Aly, OE Ismael, ... Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 600-613, 2017 | 77 | 2017 |
| Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation WM Eldehna, MF Abo-Ashour, HS Ibrahim, GH Al-Ansary, HA Ghabbour, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 686-700, 2018 | 73 | 2018 |
| Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities KAM Abouzid, GH Al-Ansary, AM El-Naggar European journal of medicinal chemistry 134, 357-365, 2017 | 73 | 2017 |
| Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and … WM Eldehna, GH Al-Ansary, S Bua, A Nocentini, P Gratteri, A Altoukhy, ... European Journal of Medicinal Chemistry 127, 521-530, 2017 | 66 | 2017 |
| Type IIA-Type IIB protein tyrosine kinase inhibitors hybridization as an efficient approach for potent multikinase inhibitor development: Design, synthesis, anti-proliferative … WM Eldehna, AM El Kerdawy, GH Al-Ansary, ST Al-Rashood, MM Ali, ... European Journal of Medicinal Chemistry 163, 37-53, 2019 | 56 | 2019 |
| Novel [(N-alkyl-3-indolylmethylene) hydrazono] oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in … T Al-Warhi, MF Abo-Ashour, H Almahli, OJ Alotaibi, MM Al-Sanea, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 1300-1309, 2020 | 53 | 2020 |
| Analogue based drug design, synthesis, molecular docking and anticancer evaluation of novel chromene sulfonamide hybrids as aromatase inhibitors and apoptosis enhancers MM Ghorab, MS Alsaid, GH Al-Ansary, GA Abdel-Latif, DA Abou El Ella European journal of medicinal chemistry 124, 946-958, 2016 | 50 | 2016 |
| Synthesis, biological evaluation and in silico studies of certain oxindole–indole conjugates as anticancer CDK inhibitors T Al-Warhi, AM El Kerdawy, N Aljaeed, OE Ismael, RR Ayyad, ... Molecules 25 (9), 2031, 2020 | 49 | 2020 |
| Molecular design and synthesis of HCV inhibitors based on thiazolone scaffold GH Al-Ansary, MAH Ismail, DA Abou El Ella, S Eid, KAM Abouzid European Journal of Medicinal Chemistry 68, 19-32, 2013 | 40 | 2013 |
| Development of 3-methyl/3-(morpholinomethyl) benzofuran derivatives as novel antitumor agents towards non-small cell lung cancer cells MM Al-Sanea, GH Al-Ansary, ZM Elsayed, RM Maklad, EB Elkaeed, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 987-999, 2021 | 22 | 2021 |
| Synthesis, crystal study, and anti-proliferative activity of some 2-benzimidazolylthioacetophenones towards triple-negative breast cancer MDA-MB-468 cells as apoptosis-inducing … HA Abdel-Aziz, WM Eldehna, H Ghabbour, GH Al-Ansary, AM Assaf, ... International Journal of Molecular Sciences 17 (8), 1221, 2016 | 21 | 2016 |
| Marine-inspired bis-indoles possessing antiproliferative activity against breast cancer; design, synthesis, and biological evaluation WM Eldehna, GS Hassan, ST Al-Rashood, HM Alkahtani, A A. Almehizia, ... Marine drugs 18 (4), 190, 2020 | 17 | 2020 |
| Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological … GH Al-Ansary, WM Eldehna, HA Ghabbour, STA Al-Rashood, ... Journal of enzyme inhibition and medicinal chemistry 32 (1), 986-991, 2017 | 17 | 2017 |
| Design and synthesis of 6-arylpyridine-tethered sulfonamides as novel selective inhibitors of carbonic anhydrase IX with promising antitumor features toward the human … WM Eldehna, EE Mohammed, GH Al-Ansary, E Berrino, MM Elbadawi, ... European Journal of Medicinal Chemistry 258, 115538, 2023 | 10 | 2023 |
| Biphenylurea/thiourea derivatives tagged with heteroarylsulfonamide motifs as novel VEGFR2 inhibitors; Design, synthesis and anti-angiogenic activity GH Al-Ansary, T Nasr, H Taha, W Fayad, S Mahgoub Bioorganic Chemistry 107, 104640, 2021 | 10 | 2021 |
| Quinoline-based small molecules as effective protein kinases inhibitors RM Aly, RA Serya, M Amira, GH Al-Ansary, DA Abou El Ella J. Am. Sci 12 (5), 10-32, 2016 | 10 | 2016 |
| Recent advancements in the development of anti-breast cancer synthetic small molecules EB Elkaeed, HAAE Salam, A Sabt, GH Al-Ansary, WM Eldehna Molecules 26 (24), 7611, 2021 | 9 | 2021 |
| Computer-based drug design, synthesis and biological evaluation of new pyrimidinone derivatives linked to arylpiperazine and 2′-carbethoxy-biphenylylmethyl moeities as α1 … MAH Ismail, DA Abou El Ella, KAM Abouzid, GHA Al-Ansary Die Pharmazie-An International Journal of Pharmaceutical Sciences 65 (11 …, 2010 | 7 | 2010 |
| An updated review of fatty acid residue-tethered heterocyclic compounds: synthetic strategies and biological significance TA Majrashi, A Sabt, HA Abd El Salam, GH Al-Ansary, MF Hamissa, ... RSC advances 13 (20), 13655-13682, 2023 | 3 | 2023 |
| Identification of novel ureido benzothiophenes as dual VEGFR-2/EGFR anticancer agents WM Eldehna, GH Al-Ansary, T Al-Warhi, MY Jaballah, M Elaasser, ... Bioorganic Chemistry 143, 107037, 2024 | 1 | 2024 |
