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Damien Rasmussen
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Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states
EW Lake, JM Muretta, AR Thompson, DM Rasmussen, A Majumdar, ...
Proceedings of the National Academy of Sciences 115 (51), E11894-E11903, 2018
652018
Allostery governs Cdk2 activation and differential recognition of CDK inhibitors
A Majumdar, DJ Burban, JM Muretta, AR Thompson, TA Engel, ...
Nature chemical biology 17 (4), 456-464, 2021
242021
Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding
EB Faber, L Sun, J Tang, E Roberts, S Ganeshkumar, N Wang, ...
Nature communications 14 (1), 3213, 2023
172023
The structure of DcrB, a lipoprotein from Salmonella enterica, reveals flexibility in the N-terminal segment of the Mog1p/PsbP-like fold
DM Rasmussen, RW Soens, TJ Davie, CK Vaneerd, B Bhattacharyya, ...
Journal of structural biology 204 (3), 513-518, 2018
72018
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors
DM Rasmussen, MM Semonis, JT Greene, JM Muretta, AR Thompson, ...
Elife 13, RP95481, 2024
32024
Development of allosteric, selective cyclin-dependent kinase 2 (CDK2) inhibitors that are negatively cooperative with cyclin binding and show potential as contraceptive agents
EB Faber, J Tang, E Roberts, S Ganeshkumar, L Sun, N Wang, ...
bioRxiv, 2022.06. 30.497818, 2022
32022
Exploring the conformational landscapes of protein kinases: perspectives from FRET and DEER
ZD Baker, DM Rasmussen, NM Levinson
Biochemical Society Transactions, BST20230558, 2024
12024
On the Allosteric Mechanisms of Paradoxical Activation by RAF Inhibitors
DM Rasmussen
University of Minnesota, 2024
2024
Thermodynamic and allosteric basis of paradoxical activation in V600E BRAF cancers
D Rasmussen, M Semonis, N Levinson
Biophysical Journal 121 (3), 144a-145a, 2022
2022
Structural and Biochemical Characterization of a Periplasmic Lipoprotein with a Role in Adaptation of Salmonella to Magnesium Limitation
JF May, DM Rasmussen, TJ Davie, C Vaneerd, EA Groisman, ...
The FASEB Journal 31, 761.11-761.11, 2017
2017
Structural Characterization of a Periplasmic Lipoprotein Associated with Magnesium Homeostasis in Salmonella enterica
DM Rasmussen, C Varneerd, B Bhattacharyya, J May
The FASEB Journal 31, 761.9-761.9, 2017
2017
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