Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine WB Chen, ZJ Wu, QL Pei, LF Cun, XM Zhang, WC Yuan Organic letters 12 (14), 3132-3135, 2010 | 331 | 2010 |
Organocatalytic direct asymmetric aldol reactions of 3-isothiocyanato oxindoles to ketones: stereocontrolled synthesis of spirooxindoles bearing highly congested contiguous … WB Chen, ZJ Wu, J Hu, LF Cun, XM Zhang, WC Yuan Organic Letters 13 (9), 2472-2475, 2011 | 207 | 2011 |
Organocatalytic Asymmetric Michael Addition of Pyrazolin‐5‐ones to Nitroolefins with Bifunctional Thiourea: Stereocontrolled Construction of Contiguous Quaternary and Tertiary … YH Liao, WB Chen, ZJ Wu, XL Du, LF Cun, XM Zhang, WC Yuan Advanced Synthesis & Catalysis 352 (5), 827-832, 2010 | 146 | 2010 |
Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione] bisoxindoles and Dispiro [imidazolidine-2-thione] bisoxindoles YY Han, WB Chen, WY Han, ZJ Wu, XM Zhang, WC Yuan Organic letters 14 (2), 490-493, 2012 | 120 | 2012 |
Highly enantioselective aldol reaction of acetaldehyde and isatins only with 4-hydroxydiarylprolinol as catalyst: Concise stereoselective synthesis of (R)-convolutamydines B … WB Chen, XL Du, LF Cun, XM Zhang, WC Yuan Tetrahedron 66 (7), 1441-1446, 2010 | 120 | 2010 |
Highly enantioselective synthesis of β‐amino acid derivatives by the Lewis base catalyzed hydrosilylation of β‐enamino esters HJ Zheng, WB Chen, ZJ Wu, JG Deng, WQ Lin, WC Yuan, XM Zhang Chemistry–A European Journal 14 (32), 9864-9867, 2008 | 117 | 2008 |
Reactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes W Chen, K Balakrishnan, Y Kuang, Y Han, M Fu, V Gandhi, X Peng Journal of medicinal chemistry 57 (11), 4498-4510, 2014 | 113 | 2014 |
Diastereo- and Enantioselective Conjugate Addition of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Ni(OAc)2-Diamine Complex under Mild … YY Han, ZJ Wu, WB Chen, XL Du, XM Zhang, WC Yuan Organic Letters 13 (19), 5064-5067, 2011 | 80 | 2011 |
Catalyst-free aldol condensation of ketones and isatins under mild reaction conditions in DMF with molecular sieves 4 Å as additive WB Chen, YH Liao, XL Du, XM Zhang, WC Yuan Green Chemistry 11 (9), 1465-1476, 2009 | 58 | 2009 |
Discovery and optimization of novel hydrogen peroxide activated aromatic nitrogen mustard derivatives as highly potent anticancer agents W Chen, H Fan, K Balakrishnan, Y Wang, H Sun, Y Fan, V Gandhi, ... Journal of Medicinal Chemistry 61 (20), 9132-9145, 2018 | 45 | 2018 |
Highly efficient synthesis of spiro [oxazolidine-2-thione-oxindoles] with 3-isothiocyanato oxindoles and aldehydes via an organocatalytic cascade aldol-cyclization reaction WB Chen, WY Han, YY Han, XM Zhang, WC Yuan Tetrahedron 69 (26), 5281-5286, 2013 | 37 | 2013 |
Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells Y Wang, H Fan, K Balakrishnan, Z Lin, S Cao, W Chen, Y Fan, QA Guthrie, ... European journal of medicinal chemistry 133, 197-207, 2017 | 36 | 2017 |
Aromatic Nitrogen Mustard‐Based Prodrugs: Activity, Selectivity, and the Mechanism of DNA Cross‐Linking W Chen, Y Han, X Peng Chemistry–A European Journal 20 (24), 7410-7418, 2014 | 35 | 2014 |
UV-induced DNA interstrand cross-linking and direct strand breaks from a new type of binitroimidazole analogue Y Han, W Chen, Y Kuang, H Sun, Z Wang, X Peng Chemical research in toxicology 28 (5), 919-926, 2015 | 15 | 2015 |
Assessment of Phenylboronic Acid Nitrogen Mustards as Potent and Selective Drug Candidates for Triple-Negative Breast Cancer H Fan, MAU Zaman, W Chen, T Ali, A Campbell, Q Zhang, NI Setu, ... ACS Pharmacology & Translational Science 4 (2), 687-702, 2021 | 10 | 2021 |
Anti-cancer agents X Peng, Y Kuang, CAO Sheng, W Chen, Y Wang US Patent 8,637,490, 2014 | 3 | 2014 |
Anti-cancer agents X Peng, Y Kuang, CAO Sheng, W Chen, Y Wang US Patent 8,962,670, 2015 | | 2015 |
Synthesis of Isatin Derivatives Y LIAO, W CHEN, X ZHANG, W YUAN | | |