| PLINK: a tool set for whole-genome association and population-based linkage analyses S Purcell, B Neale, K Todd-Brown, L Thomas, MAR Ferreira, D Bender, ... The American journal of human genetics 81 (3), 559-575, 2007 | 32422 | 2007 |
| Analysis of protein-coding genetic variation in 60,706 humans M Lek, KJ Karczewski, EV Minikel, KE Samocha, E Banks, T Fennell, ... Nature 536 (7616), 285-291, 2016 | 10312 | 2016 |
| A second generation human haplotype map of over 3.1 million SNPs International HapMap Consortium Nature 449 (7164), 851, 2007 | 9379* | 2007 |
| Second-generation PLINK: rising to the challenge of larger and richer datasets CC Chang, CC Chow, LCAM Tellier, S Vattikuti, SM Purcell, JJ Lee Gigascience 4 (1), s13742-015-0047-8, 2015 | 9325 | 2015 |
| Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7443 | 2014 |
| Common polygenic variation contributes to risk of schizophrenia and bipolar disorder International Schizophrenia Consortium Manuscript preparation Purcell Shaun ... Nature 460 (7256), 748-752, 2009 | 5244 | 2009 |
| Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3545 | 2010 |
| Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence G Genovese, AK Kähler, RE Handsaker, J Lindberg, SA Rose, ... New England Journal of Medicine 371 (26), 2477-2487, 2014 | 3384 | 2014 |
| Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels R Saxena, BF Voight, V Lyssenko, NP Burtt, PIW de Bakker, H Chen, ... Science 316 (5829), 1331-1336, 2007 | 3023 | 2007 |
| Synaptic, transcriptional and chromatin genes disrupted in autism S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, ... Nature 515 (7526), 209-215, 2014 | 2772 | 2014 |
| Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2618 | 2018 |
| Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012 | 2571 | 2012 |
| Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ... Nature genetics 45 (9), 984-994, 2013 | 2351 | 2013 |
| Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits S Purcell, SS Cherny, PC Sham Bioinformatics 19 (1), 149-150, 2003 | 2313 | 2003 |
| Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2308 | 2010 |
| Partitioning heritability by functional annotation using genome-wide association summary statistics HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ... Nature genetics 47 (11), 1228-1235, 2015 | 2242 | 2015 |
| Genome-wide detection and characterization of positive selection in human populations PC Sabeti, P Varilly, B Fry, J Lohmueller, E Hostetter, C Cotsapas, X Xie, ... Nature 449 (7164), 913-918, 2007 | 2231 | 2007 |
| Genome-wide association study identifies five new schizophrenia loci Nature genetics 43 (10), 969-976, 2011 | 2012 | 2011 |
| De novo mutations in schizophrenia implicate synaptic networks M Fromer, AJ Pocklington, DH Kavanagh, HJ Williams, S Dwyer, ... Nature 506 (7487), 179-184, 2014 | 1795 | 2014 |
| Genome-wide association analysis identifies 13 new risk loci for schizophrenia S Ripke, C O'dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, ... Nature genetics 45 (10), 1150-1159, 2013 | 1750 | 2013 |
Benjamin NealeMassachusetts General Hospital; Broad Institute; Harvard Medical School在 broadinstitute.org 的电子邮件经过验证
