| Integrated scRNA-Seq identifies human postnatal thymus seeding progenitors and regulatory dynamics of differentiating immature thymocytes M Lavaert, KL Liang, N Vandamme, JE Park, J Roels, MS Kowalczyk, B Li, ... Immunity 52 (6), 1088-1104. e6, 2020 | 98 | 2020 |
| The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation S Taveirne, S Wahlen, W Van Loocke, L Kiekens, E Persyn, E Van Ammel, ... Blood, The Journal of the American Society of Hematology 136 (3), 288-298, 2020 | 56 | 2020 |
| Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development J Roels, A Kuchmiy, M De Decker, S Strubbe, M Lavaert, KL Liang, ... Nature immunology 21 (10), 1280-1292, 2020 | 49 | 2020 |
| Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes A Buratin, M Paganin, E Gaffo, A Dal Molin, J Roels, G Germano, MT Siddi, ... Blood Advances 4 (23), 5902-5914, 2020 | 41 | 2020 |
| Targeting cytokine-and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma R De Smedt, J Morscio, L Reunes, J Roels, V Bardelli, B Lintermans, ... Blood, The Journal of the American Society of Hematology 135 (19), 1685-1695, 2020 | 32 | 2020 |
| Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development AC Dolens, K Durinck, M Lavaert, J Van der Meulen, I Velghe, J De Medts, ... EMBO reports 21 (5), e49006, 2020 | 31 | 2020 |
| RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia F Matthijssens, ND Sharma, M Nysus, CK Nickl, H Kang, DR Perez, ... The Journal of clinical investigation 131 (6), 2021 | 29 | 2021 |
| Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia J Roels, M Thénoz, B Szarzyńska, M Landfors, S De Coninck, L Demoen, ... Blood cancer discovery 1 (3), 274-289, 2020 | 28 | 2020 |
| HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development M De Decker, M Lavaert, J Roels, L Tilleman, B Vandekerckhove, ... Haematologica 106 (1), 130, 2021 | 26 | 2021 |
| Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma R De Smedt, S Peirs, J Morscio, F Matthijssens, J Roels, L Reunes, ... Haematologica 104 (1), e17, 2019 | 22 | 2019 |
| Restoration of endogenous retrovirus infectivity impacts mouse cancer models E Ottina, P Levy, U Eksmond, J Merkenschlager, GR Young, J Roels, ... Cancer immunology research 6 (11), 1292-1300, 2018 | 22 | 2018 |
| Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice T Pieters, S T’Sas, S Vanhee, A Almeida, Y Driege, J Roels, ... Journal of Experimental Medicine 218 (10), e20202280, 2021 | 20 | 2021 |
| A Tumor Suppressor Enhancer of PTEN in T-cell Development and Leukemia L Tottone, O Lancho, JW Loh, A Singh, S Kimura, J Roels, A Kuchmiy, ... Blood cancer discovery 2 (1), 92-109, 2021 | 17 | 2021 |
| SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry B Decaesteker, A Louwagie, S Loontiens, F De Vloed, SL Bekaert, ... Nature communications 14 (1), 1267, 2023 | 12 | 2023 |
| Genetic characterization and therapeutic targeting of MYC‐rearranged T cell acute lymphoblastic leukaemia G Milani, F Matthijssens, W Van Loocke, K Durinck, J Roels, S Peirs, ... British journal of haematology 185 (1), 169-174, 2019 | 11 | 2019 |
| Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development J Roels, J Van Hulle, M Lavaert, A Kuchmiy, S Strubbe, T Putteman, ... Frontiers in Immunology 13, 960918, 2022 | 9 | 2022 |
| Development of γδ T cells in the thymus–A human perspective L Boehme, J Roels, T Taghon Seminars in Immunology 61, 101662, 2022 | 7 | 2022 |
| SOX11 is a lineage-dependency factor and master epigenetic regulator in neuroblastoma B Decaesteker, A Louwagie, S Loontiens, F De Vloed, J Roels, ... bioRxiv, 2020.08. 21.261131, 2020 | 7 | 2020 |
| Szarzy nska J Roels, M Thénoz B, 0 | 6 | |
| RNA helicase DHX15 exemplifies a unique dependency in acute leukemia H Guo, J Xu, P Xing, Q Li, D Wang, C Tang, B Palhais, J Roels, J Liu, ... Haematologica 108 (8), 2029, 2023 | 5 | 2023 |
