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Samita Kafle
Samita Kafle
在 students.jefferson.edu 的电子邮件经过验证 - 首页
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A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells
GN Nguyen, JK Everett, S Kafle, AM Roche, HE Raymond, J Leiby, ...
Nature biotechnology 39 (1), 47-55, 2021
3382021
Long-term AAV-mediated factor VIII expression in nine hemophilia A dogs: a 10 year follow-up analysis on durability, safety and vector integration
GN Nguyen, JK Everett, H Raymond, S Kafle, EP Merricks, HH Kazazian, ...
Blood 134, 611, 2019
242019
Wood, 926 C., Assenmacher, CA, Merricks, EP, Long, CT, et al.(2021). A long-term study of 927 AAV gene therapy in dogs with hemophilia A identifies clonal expansions of …
GN Nguyen, JK Everett, S Kafle, AM Roche, HE Raymond, J Leiby
Nat Biotechnol 39, 47-55, 0
7
Altered cleavage of human factor VIII at the B-domain and acidic region 3 interface enhances expression after gene therapy in hemophilia A mice
GN Nguyen, JR Lindgren, MC Seleme, S Kafle, CB Zander, XL Zheng, ...
Journal of Thrombosis and Haemostasis 21 (8), 2101-2113, 2023
32023
mRNA-LNP vaccine-induced CD8+ T cells protect mice from lethal SARS-CoV-2 infection in the absence of specific antibodies
B Montoya, CR Melo-Silva, L Tang, S Kafle, P Lidskiy, C Bajusz, ...
Molecular Therapy 32 (6), 1790-1804, 2024
22024
Multiple and consecutive genome editing using i-GONAD and breeding enrichment facilitates the production of genetically modified mice
CR Melo-Silva, CJ Knudson, L Tang, S Kafle, LE Springer, J Choi, ...
Cells 12 (9), 1343, 2023
22023
Resistance to poxvirus lethality does not require the necroptosis proteins RIPK3 or MLKL
B Montoya, CJ Knudson, CR Melo-Silva, L Tang, S Kafle, LJ Sigal
Journal of Virology 97 (2), e01945-22, 2023
12023
AAV integration analysis after long term follow up in hemophilia a dogs reveals the genetic consequences of AAV-mediated gene correction
JK Everett, GN Nguyen, H Raymond, A Roche, S Kafle, C Wood, J Leiby, ...
MOLECULAR THERAPY 28 (4), 409-409, 2020
12020
The roles of CD4+ T cell help, sex, and dose in the induction of protective CD8+ T cells against a lethal poxvirus by mRNA-LNP vaccines
S Kafle, B Montoya, L Tang, YK Tam, H Muramatsu, N Pardi, LJ Sigal
Molecular Therapy-Nucleic Acids 35 (3), 2024
2024
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