BRD4 connects enhancer remodeling to senescence immune surveillance N Tasdemir, A Banito, JS Roe, D Alonso-Curbelo, M Camiolo, ... Cancer discovery 6 (6), 612-629, 2016 | 337 | 2016 |
Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells H Yuzugullu, K Benhaj, N Ozturk, S Senturk, E Celik, A Toylu, N Tasdemir, ... Molecular cancer 8, 1-20, 2009 | 305 | 2009 |
The histone chaperone CAF-1 safeguards somatic cell identity S Cheloufi, U Elling, B Hopfgartner, YL Jung, J Murn, M Ninova, ... Nature 528 (7581), 218-224, 2015 | 287 | 2015 |
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function J Sakamaki, S Wilkinson, M Hahn, N Tasdemir, J O’Prey, W Clark, ... Molecular cell 66 (4), 517-532. e9, 2017 | 221 | 2017 |
Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition JE Bolden, N Tasdemir, LE Dow, JH van Es, JE Wilkinson, Z Zhao, ... Cell reports 8 (6), 1919-1929, 2014 | 196 | 2014 |
A gene–environment-induced epigenetic program initiates tumorigenesis D Alonso-Curbelo, YJ Ho, C Burdziak, JLV Maag, JP Morris IV, ... Nature 590 (7847), 642-648, 2021 | 177 | 2021 |
Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models A Bahreini, Z Li, P Wang, KM Levine, N Tasdemir, L Cao, HM Weir, ... Breast Cancer Research 19, 1-10, 2017 | 151 | 2017 |
The SS18-SSX oncoprotein hijacks KDM2B-PRC1. 1 to drive synovial sarcoma A Banito, X Li, AN Laporte, JS Roe, F Sanchez-Vega, CH Huang, ... Cancer cell 33 (3), 527-541. e8, 2018 | 140 | 2018 |
Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism T Du, L Zhu, KM Levine, N Tasdemir, AV Lee, DAA Vignali, BV Houten, ... Scientific reports 8 (1), 1-11, 2018 | 103 | 2018 |
Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice LE Dow, Z Nasr, M Saborowski, SH Ebbesen, E Manchado, N Tasdemir, ... PloS one 9 (4), e95236, 2014 | 95 | 2014 |
Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer T Du, MJ Sikora, KM Levine, N Tasdemir, RB Riggins, SG Wendell, ... Breast Cancer Research 20, 1-15, 2018 | 86 | 2018 |
Loss of E-cadherin Enhances IGF1–IGF1R pathway activation and sensitizes breast cancers to anti-IGF1R/InsR inhibitors AM Nagle, KM Levine, N Tasdemir, JA Scott, K Burlbaugh, J Kehm, ... Clinical Cancer Research 24 (20), 5165-5177, 2018 | 72 | 2018 |
Comprehensive phenotypic characterization of human invasive lobular carcinoma cell lines in 2D and 3D cultures N Tasdemir, EA Bossart, Z Li, L Zhu, MJ Sikora, KM Levine, BM Jacobsen, ... Cancer research 78 (21), 6209-6222, 2018 | 69 | 2018 |
BRD4 connects enhancer remodeling to senescence immune surveillance. Cancer Discov. 2016; 6: 612–629. doi: 10.1158/2159-8290 N Tasdemir, A Banito, JS Roe, D Alonso-Curbelo, M Camiolo, ... CD-16-0217.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 62 | |
FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype KM Levine, N Priedigkeit, A Basudan, N Tasdemir, MJ Sikora, ES Sokol, ... NPJ breast cancer 5 (1), 19, 2019 | 56 | 2019 |
Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression L Chen, SN Vasilatos, Y Qin, TA Katz, C Cao, H Wu, N Tasdemir, ... Oncotarget 8 (47), 81737, 2017 | 49 | 2017 |
Senescent cells spread the word: non‐cell autonomous propagation of cellular senescence N Tasdemir, SW Lowe The EMBO journal 32 (14), 1975-1976, 2013 | 44 | 2013 |
Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis Z Li, Y Wu, ME Yates, N Tasdemir, A Bahreini, J Chen, KM Levine, ... Cancer research 82 (7), 1321-1339, 2022 | 38 | 2022 |
Differential regulation and targeting of estrogen receptor α turnover in invasive lobular breast carcinoma S Sreekumar, KM Levine, MJ Sikora, J Chen, N Tasdemir, D Carter, ... Endocrinology 161 (9), bqaa109, 2020 | 19 | 2020 |
Proteomic and transcriptomic profiling identifies mediators of anchorage-independent growth and roles of inhibitor of differentiation proteins in invasive lobular carcinoma N Tasdemir, K Ding, L Savariau, KM Levine, T Du, A Elangovan, ... Scientific Reports 10 (1), 11487, 2020 | 19 | 2020 |