| RAS interaction with PI3K: more than just another effector pathway E Castellano, J Downward Genes & cancer 2 (3), 261-274, 2011 | 932 | 2011 |
| Functional specificity of ras isoforms: so similar but so different E Castellano, E Santos Genes & cancer 2 (3), 216-231, 2011 | 365 | 2011 |
| Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival M Drosten, A Dhawahir, EYM Sum, J Urosevic, CG Lechuga, LM Esteban, ... The EMBO journal 29 (6), 1091-1104, 2010 | 362 | 2010 |
| Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance E Castellano, C Sheridan, MZ Thin, E Nye, B Spencer-Dene, ... Cancer cell 24 (5), 617-630, 2013 | 189 | 2013 |
| Role of RAS in the regulation of PI 3-kinase E Castellano, J Downward Phosphoinositide 3-kinase in Health and Disease: Volume 1, 143-169, 2011 | 169 | 2011 |
| RAS interaction with PI3K p110α is required for tumor-induced angiogenesis MM Murillo, S Zelenay, E Nye, E Castellano, F Lassailly, G Stamp, ... The Journal of clinical investigation 124 (8), 3601-3611, 2014 | 87 | 2014 |
| RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression E Castellano, M Molina-Arcas, AA Krygowska, P East, P Warne, A Nicol, ... Nature communications 7 (1), 11245, 2016 | 70 | 2016 |
| The crossroads between RAS and RHO signaling pathways in cellular transformation, motility and contraction O Soriano, M Alcón-Pérez, M Vicente-Manzanares, E Castellano Genes 12 (6), 819, 2021 | 58 | 2021 |
| PI3K: a crucial piece in the RAS signaling puzzle AA Krygowska, E Castellano Cold Spring Harbor perspectives in medicine 8 (6), a031450, 2018 | 58 | 2018 |
| H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity S Iborra, M Soto, L Stark-Aroeira, E Castellano, B Alarcón, C Alonso, ... Blood, The Journal of the American Society of Hematology 117 (19), 5102-5111, 2011 | 53 | 2011 |
| Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl J Gutiérrez-Berzal, E Castellano, S Martín-Encabo, N Gutiérrez-Cianca, ... Experimental cell research 312 (6), 938-948, 2006 | 52 | 2006 |
| The importance of being PI3K in the RAS signaling network C Cuesta, C Arévalo-Alameda, E Castellano Genes 12 (7), 1094, 2021 | 49 | 2021 |
| Transcriptional networks of knockout cell lines identify functional specificities of H-Ras and N-Ras: significant involvement of N-Ras in biotic and defense responses E Castellano, J De Las Rivas, C Guerrero, E Santos Oncogene 26 (6), 917-933, 2007 | 48 | 2007 |
| Tumour-suppression function of KLF12 through regulation of anoikis JD N Godin-Heymann,1 S Brabetz,1 M M Murillo,1,2 M Saponaro,3 C R Santos,4 A ... Oncogene 35 (25), 3324, 2015 | 41* | 2015 |
| R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes P Mendoza, N Martínez-Martín, ER Bovolenta, D Reyes-Garau, ... Science signaling 11 (532), eaal1506, 2018 | 32 | 2018 |
| Perfusion CT to assess angiogenesis in colon cancer: technical limitations and practical challenges S Dighe, E Castellano, H Blake, N Jeyadevan, MU Koh, M Orten, I Swift, ... The British journal of radiology 85 (1018), e814-e825, 2012 | 19 | 2012 |
| Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle E Castellano, C Guerrero, A Núñez, J De Las Rivas, E Santos Genome biology 10, 1-24, 2009 | 16 | 2009 |
| Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma FC Baltanás, R García-Navas, P Rodríguez-Ramos, N Calzada, C Cuesta, ... Nature Communications 14 (1), 5856, 2023 | 4 | 2023 |
| RAS Interaction with PI3K: More Than Just Another Effector Pathway. Genes Cancer. 2011; 2: 261–274 E Castellano, J Downward | 4 | |
| 354 Exploration of the Role of Ras–PI3K Interaction in Lung Tumor Maintenance C Sheridan, E Castellano, M Murillo, J Downward European Journal of Cancer, 108, 2012 | 1 | 2012 |
