关注
Wen Du
Wen Du
在 cumc.columbia.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits
Z Li, L Liu, Y Deng, W Ji, W Du, P Xu, L Chen, T Xu
Cell research 21 (2), 305-315, 2011
1762011
HID-1 is required for homotypic fusion of immature secretory granules during maturation
W Du, M Zhou, W Zhao, D Cheng, L Wang, J Lu, E Song, W Feng, Y Xue, ...
Elife 5, e18134, 2016
432016
Diacylglycerol guides the hopping of clathrin-coated pits along microtubules for exo-endocytosis coupling
T Yuan, L Liu, Y Zhang, L Wei, S Zhao, X Zheng, X Huang, J Boulanger, ...
Developmental cell 35 (1), 120-130, 2015
332015
Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure
J Fan, W Du, JY Kim-Muller, J Son, T Kuo, D Larrea, C Garcia, T Kitamoto, ...
Molecular metabolism 34, 97-111, 2020
272020
Contribution of different mechanisms to pancreatic beta-cell hyper-secretion in non-obese diabetic (NOD) mice during pre-diabetes
K Liang, W Du, W Zhu, S Liu, Y Cui, H Sun, B Luo, Y Xue, L Yang, L Chen, ...
Journal of Biological Chemistry 286 (45), 39537-39545, 2011
232011
HID-1 is a peripheral membrane protein primarily associated with the medial- and trans-Golgi apparatus
L Wang, Y Zhan, E Song, Y Yu, Y Jiu, W Du, J Lu, P Liu, P Xu, T Xu
Protein & cell 2 (1), 74-85, 2011
232011
Selective targeting of visceral adiposity by polycation nanomedicine
Q Wan, B Huang, T Li, Y Xiao, Y He, W Du, BZ Wang, GF Dakin, ...
Nature Nanotechnology 17 (12), 1311-1321, 2022
182022
TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver
L Wang, J Yu, Q Zhou, X Wang, M Mukhanova, W Du, L Sun, UB Pajvani, ...
Cell metabolism 34 (1), 158-170. e5, 2022
182022
Impaired maturation of large dense-core vesicles in muted-deficient adrenal chromaffin cells
Z Hao, L Wei, Y Feng, X Chen, W Du, J Ma, Z Zhou, L Chen, W Li
Journal of Cell Science 128 (7), 1365-1374, 2015
162015
Ultra-structural study of insulin granules in pancreatic β-cells of db/db mouse by scanning transmission electron microscopy tomography
Y Xue, W Zhao, W Du, X Zhang, G Ji, W Ying, T Xu
Protein & cell 3, 521-525, 2012
162012
Alterations of the Ca2+ signaling pathway in pancreatic beta-cells isolated from db/db mice
K Liang, W Du, J Lu, F Li, L Yang, Y Xue, B Hille, L Chen
Protein & Cell 5 (10), 783-794, 2014
152014
Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure
J Son, W Du, M Esposito, K Shariati, H Ding, Y Kang, D Accili
Nature communications 14 (1), 558, 2023
142023
Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals
W Du, J Wang, T Kuo, L Wang, WM McKimpson, J Son, H Watanabe, ...
The Journal of clinical investigation 132 (24), 2022
112022
Bulk-like endocytosis plays an important role in the recycling of insulin granules in pancreatic beta cells
D Wen, Y Xue, K Liang, T Yuan, J Lu, W Zhao, T Xu, L Chen
Protein & cell 3 (8), 618-626, 2012
102012
Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes
T Kitamoto, YK Lee, N Sultana, H Watanabe, WM McKimpson, W Du, ...
Molecular Metabolism 66, 101624, 2022
82022
Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes
H Watanabe, W Du, J Son, L Sui, S Asahara, IJ Kurland, T Kuo, ...
Science translational medicine 15 (681), eabq4126, 2023
62023
Single-agent Foxo1 inhibition normalizes glycemia and induces gut β-like cells in streptozotocin-diabetic mice
YK Lee, W Du, Y Nie, B Diaz, N Sultana, T Kitamoto, RL Leibel, D Accili, ...
Molecular Metabolism 66, 101618, 2022
62022
Antagonistic epistasis of Hnf4α and FoxO1 metabolic networks through enhancer interactions in β-cell function
T Kuo, W Du, Y Miyachi, PK Dadi, DA Jacobson, D Segrè, D Accili
Molecular metabolism 53, 101256, 2021
52021
Triple Notch/Tgfβ/FoxO1 blockade converts multiple intestinal sub-lineages into β-like cells and lowers glycemia in diabetic animals
W Du, J Wang, T Kuo, L Wang, WM McKimpson, J Son, H Watanabe, ...
bioRxiv, 2022.03. 21.484748, 2022
42022
Reflections on the state of diabetes research and prospects for treatment
D Accili, W Du, T Kitamoto, T Kuo, W McKimpson, Y Miyachi, ...
Diabetology international 14 (1), 21-31, 2023
32023
系统目前无法执行此操作,请稍后再试。
文章 1–20