Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model LM Refolo, MA Pappolla, B Malester, J LaFrancois, T Bryant-Thomas, ... Neurobiology of disease 7 (4), 321-331, 2000 | 1326 | 2000 |
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer’s disease A Nunomura, G Perry, MA Pappolla, R Wade, K Hirai, S Chiba, MA Smith Journal of Neuroscience 19 (6), 1959-1964, 1999 | 938 | 1999 |
Amyloid‐β deposition in Alzheimer transgenic mice is associated with oxidative stress MA Smith, K Hirai, K Hsiao, MA Pappolla, PLR Harris, SL Siedlak, ... Journal of neurochemistry 70 (5), 2212-2215, 1998 | 714 | 1998 |
A cholesterol-lowering drug reduces β-amyloid pathology in a transgenic mouse model of Alzheimer's disease LM Refolo, MA Pappolla, J LaFrancois, B Malester, SD Schmidt, ... Neurobiology of disease 8 (5), 890-899, 2001 | 705 | 2001 |
Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide MA Pappolla, M Sos, RA Omar, RJ Bick, DLM Hickson-Bick, RJ Reiter, ... Journal of Neuroscience 17 (5), 1683-1690, 1997 | 518 | 1997 |
Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease. MA Pappolla, RA Omar, KS Kim, NK Robakis The American journal of pathology 140 (3), 621, 1992 | 509 | 1992 |
Inhibition of Alzheimer β-fibrillogenesis by melatonin M Pappolla, P Bozner, C Soto, H Shao, NK Robakis, M Zagorski, ... Journal of Biological Chemistry 273 (13), 7185-7188, 1998 | 450 | 1998 |
Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant … MA Pappolla, YJ Chyan, RA Omar, K Hsiao, G Perry, MA Smith, P Bozner The American journal of pathology 152 (4), 871, 1998 | 434 | 1998 |
Neuronal oxidative stress precedes amyloid-β deposition in Down syndrome A Nunomura, G Perry, MA Pappolla, RP Friedland, K Hirai, S Chiba, ... Journal of Neuropathology & Experimental Neurology 59 (11), 1011-1017, 2000 | 429 | 2000 |
Potent neuroprotective properties against the Alzheimer β-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid YJ Chyan, B Poeggeler, RA Omar, DG Chain, B Frangione, J Ghiso, ... Journal of Biological Chemistry 274 (31), 21937-21942, 1999 | 426 | 1999 |
Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology MA Pappolla, TK Bryant-Thomas, D Herbert, J Pacheco, M Fabra Garcia, ... Neurology 61 (2), 199-205, 2003 | 410 | 2003 |
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease E Matsubara, T Bryant‐Thomas, J Pacheco Quinto, TL Henry, ... Journal of Neurochemistry 85 (5), 1101-1108, 2003 | 379 | 2003 |
Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease R J Baranello, K L Bharani, V Padmaraju, N Chopra, D K Lahiri, N H Greig, ... Current Alzheimer Research 12 (1), 32-46, 2015 | 372 | 2015 |
Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging YZ Wadghiri, EM Sigurdsson, M Sadowski, JI Elliott, Y Li, H Scholtzova, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2003 | 344 | 2003 |
Reviews of evidence regarding interventions to reduce tobacco use and exposure to environmental tobacco smoke DP Hopkins, PA Briss, CJ Ricard, CG Husten, VG Carande-Kulis, ... American journal of preventive medicine 20 (2), 16-66, 2001 | 335 | 2001 |
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease MA Pappolla, YJ Chyan, B Poeggeler, B Frangione, G Wilson, J Ghiso, ... Journal of neural transmission 107, 203-231, 2000 | 328 | 2000 |
Luteinizing hormone modulates cognition and amyloid-β deposition in Alzheimer APP transgenic mice G Casadesus, KM Webber, CS Atwood, MA Pappolla, G Perry, RL Bowen, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (4), 447-452, 2006 | 232 | 2006 |
Statin therapy for Alzheimer’s disease: will it work? SS Petanceska, S DeRosa, V Olm, N Diaz, A Sharma, T Thomas-Bryant, ... Journal of Molecular Neuroscience 19, 155-161, 2002 | 222 | 2002 |
Increased expression but reduced activity of antioxidant enzymes in Alzheimer's disease RA Omar, YJ Chyan, AC Andorn, B Poeggeler, NK Robakis, MA Pappolla Journal of Alzheimer's Disease 1 (3), 139-145, 1999 | 199 | 1999 |
Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells K Sambamurti, J Shioi, JP Anderson, MA Pappolla, NK Robakis Journal of neuroscience research 33 (2), 319-329, 1992 | 190 | 1992 |