Toll-like receptor–induced changes in glycolytic metabolism regulate dendritic cell activation CM Krawczyk, T Holowka, J Sun, J Blagih, E Amiel, RJ DeBerardinis, ... Blood, The Journal of the American Society of Hematology 115 (23), 4742-4749, 2010 | 1261 | 2010 |
Control of effector CD8+ T cell function by the transcription factor Eomesodermin EL Pearce, AC Mullen, GA Martins, CM Krawczyk, AS Hutchins, ... Science 302 (5647), 1041-1043, 2003 | 1247 | 2003 |
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b K Bachmaier, C Krawczyk, I Kozieradzki, YY Kong, T Sasaki, ... Nature 403 (6766), 211-216, 2000 | 795 | 2000 |
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling J Irie-Sasaki, T Sasaki, W Matsumoto, A Opavsky, M Cheng, G Welstead, ... Nature 409 (6818), 349-354, 2001 | 740 | 2001 |
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo J Blagih, F Coulombe, EE Vincent, F Dupuy, G Galicia-Vázquez, ... Immunity 42 (1), 41-54, 2015 | 637 | 2015 |
Serine is an essential metabolite for effector T cell expansion EH Ma, G Bantug, T Griss, S Condotta, RM Johnson, B Samborska, ... Cell metabolism 25 (2), 345-357, 2017 | 576 | 2017 |
The MAGUK family protein CARD11 is essential for lymphocyte activation H Hara, T Wada, C Bakal, I Kozieradzki, S Suzuki, N Suzuki, M Nghiem, ... Immunity 18 (6), 763-775, 2003 | 404 | 2003 |
Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction MS Jeon, A Atfield, K Venuprasad, C Krawczyk, R Sarao, C Elly, C Yang, ... Immunity 21 (2), 167-177, 2004 | 381 | 2004 |
Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap EK Griffiths, C Krawczyk, YY Kong, M Raab, SJ Hyduk, D Bouchard, ... Science 293 (5538), 2260-2263, 2001 | 342 | 2001 |
Metabolic profiling using stable isotope tracing reveals distinct patterns of glucose utilization by physiologically activated CD8+ T cells EH Ma, MJ Verway, RM Johnson, DG Roy, M Steadman, S Hayes, ... Immunity 51 (5), 856-870. e5, 2019 | 311 | 2019 |
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells C Krawczyk, K Bachmaier, T Sasaki, RG Jones, SB Snapper, D Bouchard, ... Immunity 13 (4), 463-473, 2000 | 243 | 2000 |
Interleukin-10 directly inhibits CD8+ T cell function by enhancing N-glycan branching to decrease antigen sensitivity LK Smith, GM Boukhaled, SA Condotta, S Mazouz, JJ Guthmiller, R Vijay, ... Immunity 48 (2), 299-312. e5, 2018 | 233 | 2018 |
Methionine metabolism shapes T helper cell responses through regulation of epigenetic reprogramming DG Roy, J Chen, V Mamane, EH Ma, BM Muhire, RD Sheldon, ... Cell metabolism 31 (2), 250-266. e9, 2020 | 230 | 2020 |
Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells C Krawczyk, A Oliveira-dos-Santos, T Sasaki, E Griffiths, PS Ohashi, ... Immunity 16 (3), 331-343, 2002 | 213 | 2002 |
CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly RG Jones, AR Elford, MJ Parsons, L Wu, CM Krawczyk, WC Yeh, ... The Journal of experimental medicine 196 (3), 335-348, 2002 | 196 | 2002 |
Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration H Guak, S Al Habyan, EH Ma, H Aldossary, M Al-Masri, SY Won, T Ying, ... Nature communications 9 (1), 2463, 2018 | 181 | 2018 |
Suppression of Th2 cell development by Notch ligands Delta1 and Delta4 J Sun, CJ Krawczyk, EJ Pearce The Journal of Immunology 180 (3), 1655-1661, 2008 | 129 | 2008 |
Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function L Carvalho, J Sun, C Kane, F Marshall, C Krawczyk, EJ Pearce Immunology 126 (1), 28-34, 2009 | 125 | 2009 |
The proapoptotic factors Bax and Bak regulate T cell proliferation through control of endoplasmic reticulum Ca2+ homeostasis RG Jones, T Bui, C White, M Madesh, CM Krawczyk, T Lindsten, ... Immunity 27 (2), 268-280, 2007 | 124 | 2007 |
Functional plasticity in memory T helper cell responses CM Krawczyk, H Shen, EJ Pearce The Journal of Immunology 178 (7), 4080-4088, 2007 | 122 | 2007 |