| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13238* | 2021 |
| ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ... The EMBO journal 24 (19), 3470-3481, 2005 | 910 | 2005 |
| Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ... Molecular and cellular biology 22 (21), 7405-7416, 2002 | 857 | 2002 |
| The GCN2‐ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation J Ye, M Kumanova, LS Hart, K Sloane, H Zhang, DN De Panis, ... The EMBO journal 29 (12), 2082-2096, 2010 | 737 | 2010 |
| Activating transcription factor 4 is translationally regulated by hypoxic stress JD Blais, V Filipenko, M Bi, HP Harding, D Ron, C Koumenis, BG Wouters, ... Molecular and cellular biology 24 (17), 7469-7482, 2004 | 514 | 2004 |
| The PERK/eIF2α/ATF4 module of the UPR in hypoxia resistance and tumor growth DR Fels, C Koumenis Cancer biology & therapy 5 (7), 723-728, 2006 | 487 | 2006 |
| Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation C Koumenis, R Alarcon, E Hammond, P Sutphin, W Hoffman, M Murphy, ... Molecular and cellular biology, 2001 | 474 | 2001 |
| Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma XH Ma, SF Piao, S Dey, Q Mcafee, G Karakousis, J Villanueva, LS Hart, ... The Journal of clinical investigation 124 (3), 1406-1417, 2014 | 457 | 2014 |
| ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth LS Hart, JT Cunningham, T Datta, S Dey, F Tameire, SL Lehman, BO Qiu, ... The Journal of clinical investigation 122 (12), 4621-4634, 2012 | 427 | 2012 |
| Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ... The EMBO journal 25 (5), 1114-1125, 2006 | 409 | 2006 |
| Design, implementation, and in vivo validation of a novel proton FLASH radiation therapy system ES Diffenderfer, II Verginadis, MM Kim, K Shoniyozov, A Velalopoulou, ... International Journal of Radiation Oncology* Biology* Physics 106 (2), 440-448, 2020 | 382 | 2020 |
| PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage E Bobrovnikova-Marjon, C Grigoriadou, D Pytel, F Zhang, J Ye, ... Oncogene 29 (27), 3881-3895, 2010 | 364 | 2010 |
| Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress JD Blais, CL Addison, R Edge, T Falls, H Zhao, K Wary, C Koumenis, ... Molecular and cellular biology 26 (24), 9517-9532, 2006 | 353 | 2006 |
| Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3β LK Qu, S Huang, D Baltzis, AM Rivas-Estilla, O Pluquet, M Hatzoglou, ... Genes & development 18 (3), 261-277, 2004 | 312 | 2004 |
| ER stress, hypoxia tolerance and tumor progression C Koumenis Current molecular medicine 6 (1), 55-69, 2006 | 289 | 2006 |
| " Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways C Koumenis, BG Wouters Molecular Cancer Research 4 (7), 423-436, 2006 | 284 | 2006 |
| ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis S Dey, CM Sayers, II Verginadis, SL Lehman, Y Cheng, GJ Cerniglia, ... The Journal of clinical investigation 125 (7), 2592-2608, 2015 | 270 | 2015 |
| GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2 J Ye, W Palm, M Peng, B King, T Lindsten, MO Li, C Koumenis, ... Genes & development 29 (22), 2331-2336, 2015 | 269 | 2015 |
| Effects of radiation quality and oxygen on clustered DNA lesions and cell death RD Stewart, VK Yu, AG Georgakilas, C Koumenis, JH Park, DJ Carlson Radiation research 176 (5), 587-602, 2011 | 238 | 2011 |
| miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner NS Chitnis, D Pytel, E Bobrovnikova-Marjon, D Pant, H Zheng, NL Maas, ... Molecular cell 48 (3), 353-364, 2012 | 228 | 2012 |
Ioannis I. VerginadisResearch Assistant Professor, Department of Radiation Oncology, Perelman School of Medicine, UPenn在 pennmedicine.upenn.edu 的电子邮件经过验证
