Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance M López, L Varela, MJ Vázquez, S Rodríguez-Cuenca, CR González, ... Nature medicine 16 (9), 1001-1008, 2010 | 760 | 2010 |
The gut microbiota modulates host energy and lipid metabolism in mice [S] VR Velagapudi, R Hezaveh, CS Reigstad, P Gopalacharyulu, L Yetukuri, ... Journal of lipid research 51 (5), 1101-1112, 2010 | 675 | 2010 |
Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3 SA Khan NA, Auranen M, Paetau I, Pirinen E, Euro L, Forsström S, Pasila L ... EMBO Mol Med 6 (6), 721-31, 2014 | 417 | 2014 |
Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice X Prieur, CYL Mok, VR Velagapudi, V Núñez, L Fuentes, D Montaner, ... Diabetes 60 (3), 797-809, 2011 | 415 | 2011 |
Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity M Kolak, J Westerbacka, VR Velagapudi, D Wagsater, L Yetukuri, ... Diabetes 56 (8), 1960-1968, 2007 | 378 | 2007 |
Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity J Prawitt, M Abdelkarim, JHM Stroeve, I Popescu, H Duez, VR Velagapudi, ... Diabetes 60 (7), 1861-1871, 2011 | 355 | 2011 |
mTORC1 regulates mitochondrial integrated stress response and mitochondrial myopathy progression NA Khan, J Nikkanen, S Yatsuga, C Jackson, L Wang, S Pradhan, ... Cell metabolism 26 (2), 419-428. e5, 2017 | 346 | 2017 |
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans KH Pietiläinen, T Rog, T Seppänen-Laakso, S Virtue, P Gopalacharyulu, ... PLoS biology 9 (6), e1000623, 2011 | 276 | 2011 |
Mitochondrial DNA replication defects disturb cellular dNTP pools and remodel one-carbon metabolism J Nikkanen, S Forsström, L Euro, I Paetau, RA Kohnz, L Wang, D Chilov, ... Cell metabolism 23 (4), 635-648, 2016 | 262 | 2016 |
Host-microbe co-metabolism dictates cancer drug efficacy in C. elegans TA Scott, LM Quintaneiro, P Norvaisas, PP Lui, MP Wilson, KY Leung, ... Cell 169 (3), 442-456. e18, 2017 | 243 | 2017 |
Niacin cures systemic NAD+ deficiency and improves muscle performance in adult-onset mitochondrial myopathy E Pirinen, M Auranen, NA Khan, V Brilhante, N Urho, A Pessia, ... Cell metabolism 31 (6), 1078-1090. e5, 2020 | 233 | 2020 |
Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations A Kotronen, VR Velagapudi, L Yetukuri, J Westerbacka, R Bergholm, ... Diabetologia 52, 684-690, 2009 | 212 | 2009 |
Hypothalamic AMPK-ER stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance N Martínez-Sánchez, P Seoane-Collazo, C Contreras, L Varela, ... Cell metabolism 26 (1), 212-229. e12, 2017 | 210 | 2017 |
Faecal and serum metabolomics in paediatric inflammatory bowel disease KL Kolho, A Pessia, T Jaakkola, WM de Vos, V Velagapudi Journal of Crohn's and Colitis 11 (3), 321-334, 2017 | 199 | 2017 |
Metabolomic profiling of extracellular vesicles and alternative normalization methods reveal enriched metabolites and strategies to study prostate cancer-related changes M Puhka, M Takatalo, ME Nordberg, S Valkonen, J Nandania, M Aatonen, ... Theranostics 7 (16), 3824, 2017 | 197 | 2017 |
Fibroblast growth factor 21 drives dynamics of local and systemic stress responses in mitochondrial myopathy with mtDNA deletions S Forsström, CB Jackson, CJ Carroll, M Kuronen, E Pirinen, S Pradhan, ... Cell metabolism 30 (6), 1040-1054. e7, 2019 | 187 | 2019 |
The pentose phosphate pathway regulates the circadian clock G Rey, UK Valekunja, KA Feeney, L Wulund, NB Milev, A Stangherlin, ... Cell metabolism 24 (3), 462-473, 2016 | 154 | 2016 |
Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics SU Vorrink, S Ullah, S Schmidt, J Nandania, V Velagapudi, O Beck, ... The FASEB Journal 31 (6), 2696, 2017 | 152 | 2017 |
Vitamin B12–dependent taurine synthesis regulates growth and bone mass P Roman-Garcia, I Quiros-Gonzalez, L Mottram, L Lieben, K Sharan, ... The Journal of clinical investigation 124 (7), 2988-3002, 2014 | 150 | 2014 |
Preanalytical processing and biobanking procedures of biological samples for metabolomics research: A white paper, community perspective (for “Precision medicine and … JA Kirwan, L Brennan, D Broadhurst, O Fiehn, M Cascante, WB Dunn, ... Clinical Chemistry 64 (8), 1158-1182, 2018 | 132 | 2018 |