| Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells A Eguchi, T Akuta, H Okuyama, T Senda, H Yokoi, H Inokuchi, S Fujita, ... Journal of Biological Chemistry 276 (28), 26204-26210, 2001 | 429 | 2001 |
| Protein S-guanylation by the biological signal 8-nitroguanosine 3′, 5′-cyclic monophosphate T Sawa, MH Zaki, T Okamoto, T Akuta, Y Tokutomi, S Kim-Mitsuyama, ... Nature chemical biology 3 (11), 727-735, 2007 | 308 | 2007 |
| In Vivo Antitumor Activity of Pegylated Zinc Protoporphyrin: Targeted Inhibition of Heme Oxygenase in Solid Tumor J Fang, T Sawa, T Akaike, T Akuta, SK Sahoo, G Khaled, A Hamada, ... Cancer research 63 (13), 3567-3574, 2003 | 299 | 2003 |
| Nitric oxide-induced nitrative stress involved in microbial pathogenesis MH Zaki, T Akuta, T Akaike Journal of pharmacological sciences 98 (2), 117-129, 2005 | 144 | 2005 |
| Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1α K Shiraishi, Y Ishiwata, K Nakagawa, S Yokochi, C Taruki, T Akuta, ... Clinical Cancer Research 14 (4), 1159-1166, 2008 | 126 | 2008 |
| Interleukin-1β induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner R Yasuhara, Y Miyamoto, T Akaike, T Akuta, M Nakamura, M Takami, ... Biochemical Journal 389 (2), 315-323, 2005 | 122 | 2005 |
| Molecular mechanism for activation and regulation of matrix metalloproteinases during bacterial infections and respiratory inflammation T Okamoto, T Akuta, F Tamura, A van Der Vliet, T Akaike Walter de Gruyter 385 (11), 997-1006, 2004 | 122 | 2004 |
| Proapoptotic Effect of Proteolytic Activation of Matrix Metalloproteinases by Streptococcus pyogenes Thiol Proteinase (Streptococcus Pyrogenic Exotoxin B) F Tamura, R Nakagawa, T Akuta, S Okamoto, S Hamada, H Maeda, ... Infection and immunity 72 (8), 4836-4847, 2004 | 81 | 2004 |
| Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity J Yoshitake, T Akaike, T Akuta, F Tamura, T Ogura, H Esumi, H Maeda Journal of virology 78 (16), 8709-8719, 2004 | 71 | 2004 |
| Superoxide generation mediated by 8-nitroguanosine, a highly redox-active nucleic acid derivative T Sawa, T Akaike, K Ichimori, T Akuta, K Kaneko, H Nakayama, DJ Stuehr, ... Biochemical and biophysical research communications 311 (2), 300-306, 2003 | 66 | 2003 |
| Optimization of nuclear localization signal for nuclear transport of DNA-encapsulating particles A Eguchi, H Furusawa, A Yamamoto, T Akuta, M Hasegawa, Y Okahata, ... Journal of controlled release 104 (3), 507-519, 2005 | 65 | 2005 |
| Guanine nitration in idiopathic pulmonary fibrosis and its implication for carcinogenesis Y Terasaki, T Akuta, M Terasaki, T Sawa, T Mori, T Okamoto, M Ozaki, ... American journal of respiratory and critical care medicine 174 (6), 665-673, 2006 | 62 | 2006 |
| Basic peptides as functional components of non-viral gene transfer vehicles M Nakanishi, A Eguchi, T Akuta, E Nagoshi, S Fujita, J Okabe, T Senda, ... Current Protein and Peptide Science 4 (2), 141-150, 2003 | 56 | 2003 |
| A simple and highly effective method for slow-freezing human pluripotent stem cells using dimethyl sulfoxide, hydroxyethyl starch and ethylene glycol K Imaizumi, N Nishishita, M Muramatsu, T Yamamoto, C Takenaka, ... PLoS One 9 (2), e88696, 2014 | 54 | 2014 |
| Renaturation of ovotransferrin under two-step conditions allowing primary folding of the fully reduced form and the subsequent regeneration of the intramolecular disulfides M Hirose, T Akuta, N Takahashi Journal of Biological Chemistry 264 (28), 16867-16872, 1989 | 52 | 1989 |
| Oxystress inducing antitumor therapeutics via tumor‐targeted delivery of PEG‐conjugated D‐amino acid oxidase J Fang, D Deng, H Nakamura, T Akuta, H Qin, AK Iyer, K Greish, H Maeda International journal of cancer 122 (5), 1135-1144, 2008 | 51 | 2008 |
| Involvement of Salmonella enterica serovar Typhi RpoS in resistance to NO-mediated host defense against serovar Typhi infection MS Alam, MH Zaki, J Yoshitake, T Akuta, T Ezaki, T Akaike Microbial pathogenesis 40 (3), 116-125, 2006 | 45 | 2006 |
| Protein aggregation under high concentration/density state during chromatographic and ultrafiltration processes T Arakawa, D Ejima, T Akuta International journal of biological macromolecules 95, 1153-1158, 2017 | 44 | 2017 |
| Gene transfer vectors based on Sendai virus M Nakanishi, H Mizuguchia, K Ashihara, T Senda, T Akuta, J Okabe, ... Journal of controlled release 54 (1), 61-68, 1998 | 43 | 1998 |
| Nuclear targeting of DNA M Nakanishi, T Akuta, E Nagoshi, A Eguchi, H Mizuguchi, T Senda European journal of pharmaceutical sciences 13 (1), 17-24, 2001 | 42 | 2001 |
