Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP JA Alspaugh, JR Perfect, J Heitman Genes & development 11 (23), 3206-3217, 1997 | 489 | 1997 |
Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans CA D'Souza, JA Alspaugh, C Yue, T Harashima, GM Cox, JR Perfect, ... Molecular and cellular biology, 2001 | 382 | 2001 |
The Cryptococcus neoformans capsule: a sword and a shield TR O'Meara, JA Alspaugh Clinical microbiology reviews 25 (3), 387-408, 2012 | 377 | 2012 |
RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans JA Alspaugh, LM Cavallo, JR Perfect, J Heitman Molecular microbiology 36 (2), 352-365, 2000 | 275 | 2000 |
Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans JA Alspaugh, R Pukkila-Worley, T Harashima, LM Cavallo, D Funnell, ... Eukaryotic cell 1 (1), 75-84, 2002 | 244 | 2002 |
New horizons in antifungal therapy KM Pianalto, JA Alspaugh Journal of Fungi 2 (4), 26, 2016 | 224 | 2016 |
Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis JA Alspaugh, DL Granger Infection and Immunity 59 (7), 2291-2296, 1991 | 216 | 1991 |
Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans RC Davidson, MC Cruz, RAL Sia, B Allen, JA Alspaugh, J Heitman Fungal Genetics and Biology 29 (1), 38-48, 2000 | 213 | 2000 |
Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule TR O'Meara, D Norton, MS Price, C Hay, MF Clements, CB Nichols, ... PLoS pathogens 6 (2), e1000776, 2010 | 212 | 2010 |
Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the Cryptococcus neoformans Cyclic AMP Cascade R Pukkila-Worley, QD Gerrald, PR Kraus, MJ Boily, MJ Davis, SS Giles, ... Eukaryotic cell 4 (1), 190-201, 2005 | 207 | 2005 |
Differential Effects of Inhibiting Chitin and 1,3-β-d-Glucan Synthesis in Ras and Calcineurin Mutants of Aspergillus fumigatus JR Fortwendel, PR Juvvadi, N Pinchai, BZ Perfect, JA Alspaugh, ... Antimicrobial agents and chemotherapy 53 (2), 476-482, 2009 | 169 | 2009 |
The STE12α homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans C Yue, LM Cavallo, JA Alspaugh, P Wang, GM Cox, JR Perfect, J Heitman Genetics 153 (4), 1601-1615, 1999 | 163 | 1999 |
Virulence mechanisms and Cryptococcus neoformans pathogenesis JA Alspaugh Fungal Genetics and Biology 78, 55-58, 2015 | 153 | 2015 |
Signal Transduction Pathways Regulating Differentiation and Pathogenicity ofCryptococcus neoformans JA Alspaugh, JR Perfect, J Heitman Fungal Genetics and Biology 25 (1), 1-14, 1998 | 137 | 1998 |
Cryptococcal titan cell formation is regulated by G-protein signaling in response to multiple stimuli LH Okagaki, Y Wang, ER Ballou, TR O'Meara, YS Bahn, JA Alspaugh, ... Eukaryotic cell 10 (10), 1306-1316, 2011 | 128 | 2011 |
Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans MS Waugh, CB Nichols, CM DeCesare, GM Cox, J Heitman, JA Alspaugh Microbiology 148 (1), 191-201, 2002 | 126 | 2002 |
pH response pathways in fungi: adapting to host-derived and environmental signals K Selvig, JA Alspaugh Mycobiology 39 (4), 249-256, 2011 | 124 | 2011 |
The Cryptococcus neoformans Catalase Gene Family and Its Role in Antioxidant Defense SS Giles, JE Stajich, C Nichols, QD Gerrald, JA Alspaugh, F Dietrich, ... Eukaryotic Cell 5 (9), 1447-1459, 2006 | 124 | 2006 |
Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses TR O'Meara, SM Holmer, K Selvig, F Dietrich, JA Alspaugh MBio 4 (1), 10.1128/mbio. 00522-12, 2013 | 123 | 2013 |
A Ras1‐Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans CB Nichols, ZH Perfect, JA Alspaugh Molecular microbiology 63 (4), 1118-1130, 2007 | 123 | 2007 |