RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3 CP Dillon, R Weinlich, DA Rodriguez, JG Cripps, G Quarato, P Gurung, ... Cell 157 (5), 1189-1202, 2014 | 573 | 2014 |
RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells J Martinez, LD Cunha, S Park, M Yang, Q Lu, R Orchard, QZ Li, M Yan, ... Nature 533 (7601), 115-119, 2016 | 408 | 2016 |
Survival function of the FADD-CASPASE-8-cFLIPL complex CP Dillon, A Oberst, R Weinlich, LJ Janke, TB Kang, T Ben-Moshe, ... Cell reports 1 (5), 401-407, 2012 | 347 | 2012 |
The genetic basis and cell of origin of mixed phenotype acute leukaemia TB Alexander, Z Gu, I Iacobucci, K Dickerson, JK Choi, B Xu, ... Nature 562 (7727), 373-379, 2018 | 304 | 2018 |
Crenolanib is active against models of drug-resistant FLT3-ITD− positive acute myeloid leukemia EI Zimmerman, DC Turner, J Buaboonnam, S Hu, S Orwick, MS Roberts, ... Blood, The Journal of the American Society of Hematology 122 (22), 3607-3615, 2013 | 213 | 2013 |
Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2 JA Sprowl, G Ciarimboli, CS Lancaster, H Giovinazzo, AA Gibson, G Du, ... Proceedings of the National Academy of Sciences 110 (27), 11199-11204, 2013 | 199 | 2013 |
Efficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia ML Churchman, J Low, C Qu, EM Paietta, LH Kasper, Y Chang, ... Cancer cell 28 (3), 343-356, 2015 | 195 | 2015 |
Protective roles for caspase-8 and cFLIP in adult homeostasis R Weinlich, A Oberst, CP Dillon, LJ Janke, S Milasta, JR Lukens, ... Cell reports 5 (2), 340-348, 2013 | 169 | 2013 |
Truncating erythropoietin receptor rearrangements in acute lymphoblastic leukemia I Iacobucci, Y Li, KG Roberts, SM Dobson, JC Kim, D Payne-Turner, ... Cancer cell 29 (2), 186-200, 2016 | 154 | 2016 |
Regulated lysosomal exocytosis mediates cancer progression E Machado, S White-Gilbertson, D van de Vlekkert, L Janke, S Moshiach, ... Science advances 1 (11), e1500603, 2015 | 143 | 2015 |
Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL KG Roberts, YL Yang, D Payne-Turner, W Lin, JK Files, K Dickerson, Z Gu, ... Blood advances 1 (20), 1657-1671, 2017 | 135 | 2017 |
Genomic subtyping and therapeutic targeting of acute erythroleukemia I Iacobucci, J Wen, M Meggendorfer, JK Choi, L Shi, SB Pounds, ... Nature genetics 51 (4), 694-704, 2019 | 128 | 2019 |
Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential LM Treanor, S Zhou, L Janke, ML Churchman, Z Ma, T Lu, SC Chen, ... Journal of Experimental Medicine 211 (4), 701-713, 2014 | 110 | 2014 |
Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions N Pabla, AA Gibson, M Buege, SS Ong, L Li, S Hu, G Du, JA Sprowl, ... Proceedings of the National Academy of Sciences 112 (16), 5231-5236, 2015 | 100 | 2015 |
Caspase-8-dependent inflammatory responses are controlled by its adaptor, FADD, and necroptosis B Tummers, L Mari, CS Guy, BL Heckmann, DA Rodriguez, S Rühl, ... Immunity 52 (6), 994-1006. e8, 2020 | 99 | 2020 |
ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer FC Harwood, RI Klein Geltink, BP O’Hara, M Cardone, L Janke, ... Science advances 4 (9), eaar3938, 2018 | 94 | 2018 |
PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia J Dang, L Wei, J De Ridder, X Su, AG Rust, KG Roberts, D Payne-Turner, ... Blood, The Journal of the American Society of Hematology 125 (23), 3609-3617, 2015 | 92 | 2015 |
Apoptosis-inducing-factor-dependent mitochondrial function is required for T cell but not B cell function S Milasta, CP Dillon, OE Sturm, KC Verbist, TL Brewer, G Quarato, ... Immunity 44 (1), 88-102, 2016 | 91 | 2016 |
NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs B Sundaram, N Pandian, R Mall, Y Wang, R Sarkar, HJ Kim, ... Cell 186 (13), 2783-2801. e20, 2023 | 80 | 2023 |
Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice MJ Parsons, L McCormick, L Janke, A Howard, L Bouchier-Hayes, ... Cell Death & Differentiation 20 (9), 1174-1182, 2013 | 80 | 2013 |