METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ... Cell stem cell 22 (2), 191-205. e9, 2018 | 838 | 2018 |
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia S Mi, J Lu, M Sun, Z Li, H Zhang, MB Neilly, Y Wang, Z Qian, J Jin, ... Proceedings of the National Academy of Sciences 104 (50), 19971-19976, 2007 | 671 | 2007 |
Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia Y Huang, R Su, Y Sheng, L Dong, Z Dong, H Xu, T Ni, ZS Zhang, T Zhang, ... Cancer cell 35 (4), 677-691. e10, 2019 | 620 | 2019 |
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations Z Li, J Lu, M Sun, S Mi, H Zhang, RT Luo, P Chen, Y Wang, M Yan, Z Qian, ... Proceedings of the National Academy of Sciences 105 (40), 15535-15540, 2008 | 576 | 2008 |
RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ... Cell stem cell 27 (1), 64-80. e9, 2020 | 283 | 2020 |
YAP controls endothelial activation and vascular inflammation through TRAF6 Y Lv, K Kim, Y Sheng, J Cho, Z Qian, YY Zhao, G Hu, D Pan, AB Malik, ... Circulation research 123 (1), 43-56, 2018 | 171 | 2018 |
Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel Z Qian, D Okuhara, MK Abe, MR Rosner Journal of Biological Chemistry 274 (3), 1621-1627, 1999 | 165 | 1999 |
Expression profiling of CD34+ hematopoietic stem/progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia Z Qian, AA Fernald, LA Godley, RA Larson, MM Le Beau Proceedings of the National Academy of Sciences 99 (23), 14925-14930, 2002 | 164 | 2002 |
Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation N Trakul, RE Menard, GR Schade, Z Qian, MR Rosner Journal of Biological Chemistry 280 (26), 24931-24940, 2005 | 157 | 2005 |
Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia Z Qian, JM Joslin, TR Tennant, SC Reshmi, DJ Young, A Stoddart, ... Chemico-biological interactions 184 (1-2), 50-57, 2010 | 149 | 2010 |
Endothelial and smooth muscle cell interaction via FoxM1 signaling mediates vascular remodeling and pulmonary hypertension Z Dai, MM Zhu, Y Peng, H Jin, N Machireddy, Z Qian, X Zhang, YY Zhao American journal of respiratory and critical care medicine 198 (6), 788-802, 2018 | 125 | 2018 |
Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame L Shao, W Feng, Y Sun, H Bai, J Liu, C Currie, J Kim, R Gama, Z Wang, ... Cell research 19 (3), 296-306, 2009 | 123 | 2009 |
Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del (5q) F Lai, LA Godley, J Joslin, AA Fernald, J Liu, R Espinosa III, N Zhao, ... Genomics 71 (2), 235-245, 2001 | 117 | 2001 |
Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response F Yu, J Wei, X Cui, C Yu, W Ni, J Bungert, L Wu, C He, Z Qian Nucleic acids research 49 (10), 5779-5797, 2021 | 111 | 2021 |
A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex–mediated DNA replication Y Sheng, J Wei, F Yu, H Xu, C Yu, Q Wu, Y Liu, L Li, X Cui, X Gu, B Shen, ... Blood, The Journal of the American Society of Hematology 138 (26), 2838-2852, 2021 | 98 | 2021 |
Activation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cells M Ming, S Wang, W Wu, V Senyuk, MM Le Beau, G Nucifora, Z Qian Journal of biological chemistry 287 (27), 22683-22690, 2012 | 98 | 2012 |
Critical role of miR-9 in myelopoiesis and EVI1-induced leukemogenesis V Senyuk, Y Zhang, Y Liu, M Ming, K Premanand, L Zhou, P Chen, ... Proceedings of the National Academy of Sciences 110 (14), 5594-5599, 2013 | 90 | 2013 |
The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation C Tiruppathi, D Soni, DM Wang, J Xue, V Singh, PB Thippegowda, ... Nature immunology 15 (3), 239-247, 2014 | 84 | 2014 |
Cloning and characterization of MST4, a novel Ste20-like kinase Z Qian, C Lin, R Espinosa, M LeBeau, MR Rosner Journal of Biological Chemistry 276 (25), 22439-22445, 2001 | 84 | 2001 |
Haploinsufficiency of Apc leads to ineffective hematopoiesis J Wang, AA Fernald, J Anastasi, MM Le Beau, Z Qian Blood, The Journal of the American Society of Hematology 115 (17), 3481-3488, 2010 | 83 | 2010 |