| Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8+ T cell responses S Keller, JT Wilson, GI Patilea, HB Kern, AJ Convertine, PS Stayton Journal of Controlled Release 191, 24-33, 2014 | 146 | 2014 |
| Drug concentration asymmetry in tissues and plasma for small molecule–related therapeutic modalities D Zhang, CECA Hop, G Patilea-Vrana, G Gampa, HK Seneviratne, ... Drug Metabolism and Disposition 47 (10), 1122-1135, 2019 | 101 | 2019 |
| Development of a novel maternal-fetal physiologically based pharmacokinetic model I: insights into factors that determine fetal drug exposure through simulations and … Z Zhang, MZ Imperial, GI Patilea-Vrana, J Wedagedera, L Gaohua, ... Drug Metabolism and Disposition 45 (8), 920-938, 2017 | 94 | 2017 |
| Transport vs. metabolism: what determines the pharmacokinetics and pharmacodynamics of drugs? Insights from the extended clearance model G Patilea‐Vrana, JD Unadkat Clinical Pharmacology & Therapeutics 100 (5), 413-418, 2016 | 92 | 2016 |
| A marijuana-drug interaction primer: precipitants, pharmacology, and pharmacokinetics EJ Cox, N Maharao, G Patilea-Vrana, JD Unadkat, AE Rettie, JS McCune, ... Pharmacology & therapeutics 201, 25-38, 2019 | 89 | 2019 |
| Enhancement of microbiota in healthy macaques results in beneficial modulation of mucosal and systemic immune function JA Manuzak, T Hensley-McBain, AS Zevin, C Miller, R Cubas, J Gile, ... The Journal of Immunology 196 (5), 2401-2409, 2016 | 53 | 2016 |
| Hepatic enzymes relevant to the disposition of (−)-∆ 9-tetrahydrocannabinol (THC) and its psychoactive metabolite, 11-OH-THC GI Patilea-Vrana, O Anoshchenko, JD Unadkat Drug Metabolism and Disposition 47 (3), 249-256, 2019 | 27 | 2019 |
| Quantifying hepatic enzyme kinetics of (-)-∆ 9-Tetrahydrocannabinol (THC) and its psychoactive metabolite, 11-OH-THC, through in vitro modeling GI Patilea-Vrana, JD Unadkat Drug Metabolism and Disposition 47 (7), 743-752, 2019 | 21 | 2019 |
| Characterizing and quantifying extrahepatic metabolism of (−)-Δ9-tetrahydrocannabinol (THC) and its psychoactive metabolite,(±)-11-hydroxy-Δ9-THC (11-OH-THC) AR Kumar, GI Patilea-Vrana, O Anoshchenko, JD Unadkat Drug metabolism and disposition 50 (6), 734-740, 2022 | 14 | 2022 |
| Development and Verification of a Linked Δ9-THC/11-OH-THC Physiologically Based Pharmacokinetic Model in Healthy, Nonpregnant Population and Extrapolation to Pregnant Women GI Patilea-Vrana, JD Unadkat Drug Metabolism and Disposition 49 (7), 509-520, 2021 | 14 | 2021 |
| Hepatic enzymes relevant to the disposition of (-)-Δ 9-tetrahydrocannabinol (THC) and its psychoactive metabolite GI Patilea-Vrana, O Anoshchenko, JD Unadkat | 13 | 2019 |
| Quantifying hepatic enzyme kinetics of (-)-Δ 9-tetrahydrocannabinol (THC) and its psychoactive metabolite GI Patilea-Vrana, JD Unadkat | 11 | 2019 |
| When does the rate-determining step in the hepatic clearance of a drug switch from sinusoidal uptake to all hepatobiliary clearances? Implications for predicting drug-drug … GI Patilea-Vrana, JD Unadkat Drug Metabolism and Disposition 46 (11), 1487-1496, 2018 | 11 | 2018 |
| Development and verification of a linked ᵪB; 9-THC/11-OH-THC physiologically-based pharmacokinetic (PBPK) model in healthy, non-pregnant population and extrapolation to … GI Patilea-Vrana, JD Unadkat Drug Metabolism and Disposition, 2021 | | 2021 |
| P216-Development and verification of a linked THC/11-OH-THC PBPK model in healthy subjects and extrapolation to pregnancy JD Unadkat, G Patilea-Vrana Drug Metabolism and Pharmacokinetics 35 (1), S88, 2020 | | 2020 |
