M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages GR Gunassekaran, SMP Vadevoo, MC Baek, B Lee Biomaterials 278, 121137, 2021 | 298 | 2021 |
The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages SMP Vadevoo, GR Gunassekaran, CE Lee, NH Lee, J Lee, S Chae, ... Proceedings of the National Academy of Sciences 118 (37), e2102434118, 2021 | 81 | 2021 |
Peptides as multifunctional players in cancer therapy SMP Vadevoo, S Gurung, HS Lee, GR Gunassekaran, SM Lee, JW Yoon, ... Experimental & Molecular Medicine 55 (6), 1099-1109, 2023 | 66 | 2023 |
Enhanced delivery of liposomes to lung tumor through targeting interleukin-4 receptor on both tumor cells and tumor endothelial cells L Chi, MH Na, HK Jung, SMP Vadevoo, CW Kim, G Padmanaban, TI Park, ... Journal of Controlled Release 209, 327-336, 2015 | 60 | 2015 |
Phage display-identified PD-L1-binding peptides reinvigorate T-cell activity and inhibit tumor progression S Gurung, F Khan, GR Gunassekaran, J Do Yoo, SMP Vadevoo, ... Biomaterials 247, 119984, 2020 | 53 | 2020 |
Peptide-based targeted therapeutics and apoptosis imaging probes for cancer therapy SMP Vadevoo, S Gurung, F Khan, ME Haque, GR Gunassekaran, L Chi, ... Archives of pharmacal research 42, 150-158, 2019 | 35 | 2019 |
IL4 Receptor–targeted proapoptotic peptide blocks tumor growth and metastasis by enhancing antitumor immunity SMP Vadevoo, JE Kim, GR Gunassekaran, HK Jung, L Chi, DE Kim, ... Molecular Cancer Therapeutics 16 (12), 2803-2816, 2017 | 34 | 2017 |
Identification of novel CD44v6-binding peptides that block CD44v6 and deliver a pro-apoptotic peptide to tumors to inhibit tumor growth and metastasis in mice F Khan, S Gurung, GR Gunassekaran, SMP Vadevoo, L Chi, U Permpoon, ... Theranostics 11 (3), 1326, 2021 | 27 | 2021 |
Designed ferritin nanocages displaying trimeric TRAIL and tumor-targeting peptides confer superior anti-tumor efficacy JD Yoo, SM Bae, J Seo, IS Jeon, SMP Vadevoo, SY Kim, IS Kim, B Lee, ... Scientific reports 10 (1), 19997, 2020 | 18 | 2020 |
Non-genetic engineering of cytotoxic T cells to target IL-4 receptor enhances tumor homing and therapeutic efficacy against melanoma GR Gunassekaran, CM Hong, SMP Vadevoo, L Chi, P Guruprasath, ... Biomaterials 159, 161-173, 2018 | 16 | 2018 |
Interleukin-4 receptor targeting peptide decorated extracellular vesicles as a platform for in vivo drug delivery to thyroid cancer P Gangadaran, GR Gunassekaran, RL Rajendran, JM Oh, SMP Vadevoo, ... Biomedicines 10 (8), 1978, 2022 | 13 | 2022 |
A phage display-identified peptide selectively binds to kidney injury molecule-1 (KIM-1) and detects KIM-1-overexpressing tumors in vivo ME Haque, F Khan, L Chi, S Gurung, SMP Vadevoo, RW Park, DK Kim, ... Cancer Res Treat 51 (3), 861-875, 2019 | 12 | 2019 |
Epigenetic therapy reprograms M2-type tumor-associated macrophages into an M1-like phenotype by upregulating miR-7083-5p SMP Vadevoo, GR Gunassekaran, JD Yoo, TH Kwon, K Hur, S Chae, ... Frontiers in Immunology 13, 976196, 2022 | 9 | 2022 |
Inhibition of tumor growth against chemoresistant cholangiocarcinoma by a proapoptotic peptide targeting interleukin-4 receptor U Permpoon, F Khan, SMP Vadevoo, S Gurung, GR Gunassekaran, ... Molecular Pharmaceutics 17 (11), 4077-4088, 2020 | 9 | 2020 |
IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and … SMP Vadevoo, Y Kang, GR Gunassekaran, SM Lee, MS Park, DG Jo, ... Theranostics 14 (6), 2605, 2024 | 4 | 2024 |
Pharmaceutical composition that is anticancer and suppresses cancer metastasis, containing, as active ingredient, fusion peptide simultaneously targeting cancer cell and tumor … BH Lee, SMP Vadevoo US Patent App. 15/856,740, 2018 | 2 | 2018 |
Inhibition of tumor growth using exosomes loaded with KRAS siRNA and surface-modified with tumor-targeted proapoptotic peptide L Kang, S Jeon, SM Vadevoo, SH Kim, B Lee Cancer Research 84 (6_Supplement), 5748-5748, 2024 | 1 | 2024 |
Interleukin-4 receptor-targeted Abraxane inhibits tumor growth by enhancing drug delivery and reprogramming of M2-type macrophages into M1 phenotype PVS Murugan, GG Rangaswamy, B Lee Cancer Research 82 (12_Supplement), 245-245, 2022 | 1 | 2022 |
Use of odorant receptor for suppressing lactate-induced m2-type differentiation of tumor-associated macrophages and tumor growth BH Lee, J Koo, PVSRI MURUGAN US Patent App. 18/287,048, 2024 | | 2024 |
Peptide selectively binding to cancer cell-derived exosome, and uses thereof BH Lee, C Youngji, K Fatima, SMP Vadevoo, GR Gunassekaran US Patent App. 18/020,082, 2023 | | 2023 |