Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model E Spangenberg, PL Severson, LA Hohsfield, J Crapser, J Zhang, ... Nature communications 10 (1), 3758, 2019 | 667 | 2019 |
Functional differences between microglia and monocytes after ischemic stroke RM Ritzel, AR Patel, JM Grenier, J Crapser, R Verma, ER Jellison, ... Journal of neuroinflammation 12, 1-12, 2015 | 305 | 2015 |
One is the deadliest number: the detrimental effects of social isolation on cerebrovascular diseases and cognition B Friedler, J Crapser, L McCullough Acta neuropathologica 129, 493-509, 2015 | 211 | 2015 |
To kill a microglia: a case for CSF1R inhibitors KN Green, JD Crapser, LA Hohsfield Trends in immunology 41 (9), 771-784, 2020 | 194 | 2020 |
Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain JD Crapser, EE Spangenberg, RA Barahona, MA Arreola, LA Hohsfield, ... EBioMedicine 58, 2020 | 179 | 2020 |
Age-associated resident memory CD8 T cells in the central nervous system are primed to potentiate inflammation after ischemic brain injury RM Ritzel, J Crapser, AR Patel, R Verma, JM Grenier, A Chauhan, ... The Journal of Immunology 196 (8), 3318-3330, 2016 | 174 | 2016 |
Aging alters the immunological response to ischemic stroke RM Ritzel, YJ Lai, JD Crapser, AR Patel, A Schrecengost, JM Grenier, ... Acta neuropathologica 136, 89-110, 2018 | 172 | 2018 |
Ischemic stroke induces gut permeability and enhances bacterial translocation leading to sepsis in aged mice J Crapser, R Ritzel, R Verma, VR Venna, F Liu, A Chauhan, E Koellhoffer, ... Aging (Albany NY) 8 (5), 1049, 2016 | 170 | 2016 |
Age-and location-related changes in microglial function RM Ritzel, AR Patel, S Pan, J Crapser, M Hammond, E Jellison, ... Neurobiology of aging 36 (6), 2153-2163, 2015 | 147 | 2015 |
Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease JD Crapser, J Ochaba, N Soni, JC Reidling, LM Thompson, KN Green Brain 143 (1), 266-288, 2020 | 115 | 2020 |
Microglia as hackers of the matrix: sculpting synapses and the extracellular space JD Crapser, MA Arreola, KI Tsourmas, KN Green Cellular & molecular immunology 18 (11), 2472-2488, 2021 | 94 | 2021 |
A limited capacity for microglial repopulation in the adult brain AR Najafi, J Crapser, S Jiang, W Ng, A Mortazavi, BL West, KN Green Glia 66 (11), 2385-2396, 2018 | 92 | 2018 |
Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk RM Ritzel, AR Patel, M Spychala, R Verma, J Crapser, EC Koellhoffer, ... Proceedings of the National Academy of Sciences 114 (28), E5673-E5682, 2017 | 49 | 2017 |
CD200-CD200R1 inhibitory signaling prevents spontaneous bacterial infection and promotes resolution of neuroinflammation and recovery after stroke RM Ritzel, A Al Mamun, J Crapser, R Verma, AR Patel, BE Knight, ... Journal of neuroinflammation 16, 1-16, 2019 | 47 | 2019 |
Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R+/− mouse model of ALSP, which can be rescued via CSF1R inhibitors MA Arreola, N Soni, JD Crapser, LA Hohsfield, MRP Elmore, DP Matheos, ... Science advances 7 (35), eabg1601, 2021 | 45 | 2021 |
Reversal of the detrimental effects of post-stroke social isolation by pair-housing is mediated by activation of BDNF-MAPK/ERK in aged mice R Verma, NM Harris, BD Friedler, J Crapser, AR Patel, V Venna, ... Scientific reports 6 (1), 25176, 2016 | 38 | 2016 |
Early retinal inflammatory biomarkers in the middle cerebral artery occlusion model of ischemic stroke RM Ritzel, SJ Pan, R Verma, J Wizeman, J Crapser, AR Patel, ... Molecular Vision 22, 575, 2016 | 33 | 2016 |
Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, J Crapser, DXF Velez, ... Elife 10, e66738, 2021 | 31 | 2021 |
Evaluation of the neuroprotective effect of Sirt3 in experimental stroke R Verma, RM Ritzel, J Crapser, BD Friedler, LD McCullough Translational stroke research 10, 57-66, 2019 | 26 | 2019 |
Inhibition of mitochondrial p53 abolishes the detrimental effects of social isolation on ischemic brain injury VR Venna, R Verma, LM O’Keefe, Y Xu, J Crapser, B Friedler, ... stroke 45 (10), 3101-3104, 2014 | 26 | 2014 |