Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes C Bertolotto, P Abbe, TJ Hemesath, K Bille, DE Fisher, JP Ortonne, ... The Journal of cell biology 142 (3), 827-835, 1998 | 609 | 1998 |
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma C Bertolotto, F Lesueur, S Giuliano, T Strub, M De Lichy, K Bille, P Dessen, ... Nature 480 (7375), 94-98, 2011 | 599 | 2011 |
Cyclic AMP a key messenger in the regulation of skin pigmentation R Busca, R Ballotti Pigment Cell Research 13 (2), 60-69, 2000 | 599 | 2000 |
Fifteen‐year quest for microphthalmia‐associated transcription factor target genes Y Cheli, M Ohanna, R Ballotti, C Bertolotto Pigment cell & melanoma research 23 (1), 27-40, 2010 | 427 | 2010 |
Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis. C Roméro-Graillet, E Aberdam, M Clément, JP Ortonne, R Ballotti The Journal of clinical investigation 99 (4), 635-642, 1997 | 417 | 1997 |
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms T Tomic, T Botton, M Cerezo, G Robert, F Luciano, A Puissant, P Gounon, ... Cell death & disease 2 (9), e199-e199, 2011 | 344 | 2011 |
Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of … C Bertolotto, R Buscà, P Abbe, K Bille, E Aberdam, JP Ortonne, R Ballotti Molecular and cellular biology 18 (2), 694-702, 1998 | 321 | 1998 |
Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma T Strub, S Giuliano, T Ye, C Bonet, C Keime, D Kobi, S Le Gras, ... Oncogene 30 (20), 2319-2332, 2011 | 287 | 2011 |
Senescent cells develop a PARP-1 and nuclear factor-κB-associated secretome (PNAS) M Ohanna, S Giuliano, C Bonet, V Imbert, V Hofman, J Zangari, K Bille, ... Genes & development 25 (12), 1245-1261, 2011 | 275 | 2011 |
Mitogen-activated Protein Kinase Pathway and AP-1 Are Activated during cAMP-induced Melanogenesis in B-16 Melanoma Cells (∗) W Englaro, R Rezzonico, M Durand-Clément, D Lallemand, JP Ortonne, ... Journal of Biological Chemistry 270 (41), 24315-24320, 1995 | 269 | 1995 |
Ultraviolet B radiation acts through the nitric oxide and cGMP signal transduction pathway to stimulate melanogenesis in human melanocytes C Roméro-Graillet, E Aberdam, N Biagoli, W Massabni, JP Ortonne, ... Journal of Biological Chemistry 271 (45), 28052-28056, 1996 | 262 | 1996 |
Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny Y Cheli, S Guiliano, T Botton, S Rocchi, V Hofman, P Hofman, ... Oncogene 30 (20), 2307-2318, 2011 | 252 | 2011 |
Compounds triggering ER stress exert anti-melanoma effects and overcome BRAF inhibitor resistance M Cerezo, A Lehraiki, A Millet, F Rouaud, M Plaisant, E Jaune, T Botton, ... Cancer cell 29 (6), 805-819, 2016 | 241 | 2016 |
The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion N Fenouille, M Tichet, M Dufies, A Pottier, A Mogha, JK Soo, S Rocchi, ... PloS one 7 (7), e40378, 2012 | 241 | 2012 |
Ras mediates the cAMP‐dependent activation of extracellular signal‐regulated kinases (ERKs) in melanocytes P Abbe, F Mantoux, E Aberdam, C Peyssonnaux, A Eychène, JP Ortonne, ... The EMBO Journal, 2000 | 239 | 2000 |
Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice Y Le Marchand-Brustel, T Grémeaux, R Ballotti, E Van Obberghen Nature 315 (6021), 676-679, 1985 | 235 | 1985 |
Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner M Cerezo, M Tichet, P Abbe, M Ohanna, A Lehraiki, F Rouaud, M Allegra, ... Molecular cancer therapeutics 12 (8), 1605-1615, 2013 | 232 | 2013 |
Direct regulation of the Microphthalmia promoter by Sox10 links Waardenburg-Shah syndrome (WS4)-associated hypopigmentation and deafness to WS2 M Lee, J Goodall, CR Goding, C Verastegui, R Ballotti Journal of Biological Chemistry 275 (48), 37978-37983, 2000 | 217 | 2000 |
Regulation of the microphthalmia-associated transcription factor gene by the Waardenburg syndrome type 4 gene, SOX10 C Verastegui, K Bille, JP Ortonne, R Ballotti Journal of Biological Chemistry 275 (40), 30757-30760, 2000 | 216 | 2000 |
Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation W Englaro, C Bertolotto, A Brunet, G Pagès, JP Ortonne, R Ballotti Journal of Biological Chemistry 273 (16), 9966-9970, 1998 | 210 | 1998 |