Targeting CAG repeat RNAs reduces Huntington’s disease phenotype independently of huntingtin levels L Rué, M Bañez-Coronel, J Creus-Muncunill, A Giralt, R Alcalá-Vida, ... The Journal of clinical investigation 126 (11), 4319-4330, 2016 | 80 | 2016 |
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons ME Hauberg, J Creus-Muncunill, J Bendl, A Kozlenkov, B Zeng, C Corwin, ... Nature communications 11 (1), 5581, 2020 | 59 | 2020 |
Increased translation as a novel pathogenic mechanism in Huntington’s disease J Creus-Muncunill, R Badillos-Rodríguez, M Garcia-Forn, M Masana, ... Brain 142 (10), 3158-3175, 2019 | 48 | 2019 |
Cell-autonomous and non-cell-autonomous pathogenic mechanisms in Huntington's disease: insights from in vitro and in vivo models J Creus-Muncunill, ME Ehrlich Neurotherapeutics 16 (4), 957-978, 2019 | 47 | 2019 |
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels BJ Bailus, SM Scheeler, J Simons, MA Sanchez, KT Tshilenge, ... Autophagy 17 (12), 4119-4140, 2021 | 33 | 2021 |
Neuron type‐specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease R Alcalá‐Vida, M Garcia‐Forn, C Castany‐Pladevall, J Creus‐Muncunill, ... EMBO Molecular Medicine 13 (2), e12105, 2021 | 33 | 2021 |
Early down-regulation of PKCδ as a pro-survival mechanism in Huntington’s disease L Rue, R Alcala-Vida, G Lopez-Soop, J Creus-Muncunill, J Alberch, ... Neuromolecular medicine 16, 25-37, 2014 | 20 | 2014 |
Huntington’s disease brain-derived small RNAs recapitulate associated neuropathology in mice J Creus-Muncunill, A Guisado-Corcoll, V Venturi, L Pantano, G Escaramís, ... Acta Neuropathologica 141, 565-584, 2021 | 17 | 2021 |
Synaptic RTP801 contributes to motor-learning dysfunction in Huntington’s disease N Martín-Flores, L Pérez-Sisqués, J Creus-Muncunill, M Masana, S Ginés, ... Cell Death & Disease 11 (7), 569, 2020 | 13 | 2020 |
Striatal cholinergic dysregulation after neonatal decrease in X‐linked dystonia parkinsonism‐related TAF1 isoforms MD Cirnaru, J Creus‐Muncunill, S Nelson, TB Lewis, J Watson, ... Movement Disorders 36 (12), 2780-2794, 2021 | 12 | 2021 |
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation MD Cirnaru, S Song, KT Tshilenge, C Corwin, J Mleczko, CG Aguirre, ... Elife 10, e65979, 2021 | 11 | 2021 |
Increased levels of rictor prevent mutant huntingtin-induced neuronal degeneration J Creus-Muncunill, L Rué, R Alcalá-Vida, R Badillos-Rodríguez, ... Molecular Neurobiology 55, 7728-7742, 2018 | 11 | 2018 |
Striatal dopamine induced ERK phosphorylation is altered in mouse models of monogenic dystonia C Melis, G Beauvais, BS Muntean, MD Cirnaru, G Otrimski, ... Movement Disorders 36 (5), 1147-1157, 2021 | 8 | 2021 |
B10 nuclear lamina is differentially altered in huntington’s disease brain regions R Alcalá, J Creus-Muncunill, G Azkona, J Alberch, E Pérez-Navarro Journal of Neurology, Neurosurgery & Psychiatry 85 (Suppl 1), A12-A12, 2014 | 4 | 2014 |
Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice AD Dunn, SA Robinson, C Nwokafor, M Estill, J Ferrante, L Shen, ... Frontiers in Behavioral Neuroscience 17, 1202099, 2023 | 3 | 2023 |
Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease S Song, J Creus Muncunill, C Galicia Aguirre, KT Tshilenge, BW Hamilton, ... Biomedicines 10 (10), 2377, 2022 | 3 | 2022 |
Transcriptional and epigenetic characterization of early striosomes identifies foxf2 and olig2 as factors required for development of striatal compartmentation and neuronal … MD Cirnaru, S Song, KT Tshilenge, C Corwin, J Mleczko, CG Aguirre, ... bioRxiv, 2020.05. 19.105171, 2020 | 2 | 2020 |
TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates … J Creus-Muncunill, JV Haure-Mirande, D Mattei, J Bons, AV Ramirez, ... Journal of Neuroinflammation 21 (1), 66, 2024 | | 2024 |
Neonatal Opioid Withdrawal Syndrome in Mice: Acute Molecular and Long‐Term Behavioral Consequences JR Ferrante, AD Dunn, J Mengaziol, J Noreck, CO Lemchi, ... The FASEB Journal 36, 2022 | | 2022 |
Deletion of the microglial transmembrane immune signaling adaptor TYROBP ameliorates Huntington’s disease mouse phenotype J Creus-Muncunill, D Mattei, J Bons, AV Ramirez-Jimenez, BW Hamilton, ... bioRxiv, 2022.02. 18.480944, 2022 | | 2022 |