| Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation P Kavsak, RK Rasmussen, CG Causing, S Bonni, H Zhu, GH Thomsen, ... Molecular cell 6 (6), 1365-1375, 2000 | 1769 | 2000 |
| A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation H Zhu, P Kavsak, S Abdollah, JL Wrana, GH Thomsen Nature 400 (6745), 687-693, 1999 | 1152 | 1999 |
| Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION ... Anesthesiology 120 (3), 564-578, 2014 | 943 | 2014 |
| Association of postoperative high-sensitivity troponin levels with myocardial injury and 30-day mortality among patients undergoing noncardiac surgery PJ Devereaux, BM Biccard, A Sigamani, D Xavier, MTV Chan, ... Jama 317 (16), 1642-1651, 2017 | 757 | 2017 |
| TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation S Bonni, HR Wang, CG Causing, P Kavsak, SL Stroschein, K Luo, ... Nature Cell Biology 3 (6), 587-595, 2001 | 422 | 2001 |
| Clinical laboratory practice recommendations for the use of cardiac troponin in acute coronary syndrome: expert opinion from the Academy of the American Association for … AHB Wu, RH Christenson, DN Greene, AS Jaffe, PA Kavsak, ... Clinical chemistry 64 (4), 645-655, 2018 | 417 | 2018 |
| Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain AA Ogunjimi, DJ Briant, N Pece-Barbara, C Le Roy, GM Di Guglielmo, ... Molecular cell 19 (3), 297-308, 2005 | 345 | 2005 |
| Application of high-sensitivity troponin in suspected myocardial infarction JT Neumann, R Twerenbold, F Ojeda, NA Sörensen, AR Chapman, ... New England Journal of Medicine 380 (26), 2529-2540, 2019 | 293 | 2019 |
| Assessing the requirement for the 6-hour interval between specimens in the American Heart Association Classification of Myocardial Infarction in Epidemiology and Clinical … AR MacRae, PA Kavsak, V Lustig, R Bhargava, R Vandersluis, ... Clinical chemistry 52 (5), 812-818, 2006 | 286 | 2006 |
| Association of high-sensitivity cardiac troponin I concentration with cardiac outcomes in patients with suspected acute coronary syndrome AR Chapman, KK Lee, DA McAllister, L Cullen, JH Greenslade, ... Jama 318 (19), 1913-1924, 2017 | 246 | 2017 |
| Analytic and clinical utility of a next-generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury PA Kavsak, AR MacRae, MJ Yerna, AS Jaffe Clinical chemistry 55 (3), 573-577, 2009 | 211 | 2009 |
| Plasma IL-6 and IL-10 concentrations predict AKI and long-term mortality in adults after cardiac surgery WR Zhang, AX Garg, SG Coca, PJ Devereaux, J Eikelboom, P Kavsak, ... Journal of the American Society of Nephrology 26 (12), 3123-3132, 2015 | 192 | 2015 |
| Preoperative N-Terminal Pro–B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery: A Cohort Study E Duceppe, A Patel, MTV Chan, O Berwanger, G Ackland, PA Kavsak, ... Annals of internal medicine 172 (2), 96-104, 2020 | 156 | 2020 |
| Assessment of the European Society of Cardiology 0-hour/1-hour algorithm to rule-out and rule-in acute myocardial infarction JW Pickering, JH Greenslade, L Cullen, D Flaws, W Parsonage, S Aldous, ... Circulation 134 (20), 1532-1541, 2016 | 134 | 2016 |
| The impact of the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays on the frequency of acute myocardial infarction PA Kavsak, AR MacRae, V Lustig, R Bhargava, R Vandersluis, ... American heart journal 152 (1), 118-125, 2006 | 124 | 2006 |
| Short-and long-term risk stratification using a next-generation, high-sensitivity research cardiac troponin I (hs-cTnI) assay in an emergency department chest pain population PA Kavsak, X Wang, DT Ko, AR MacRae, AS Jaffe Clinical chemistry 55 (10), 1809-1815, 2009 | 117 | 2009 |
| Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION) Writing Group, on behalf of The Vascular events In noncardiac Surgery patIents cOhort evaluatioN … F Botto, P Alonso-Coello, MT Chan, JC Villar, D Xavier, S Srinathan, ... Anesthesiology 120 (3), 564-78, 2014 | 116 | 2014 |
| High-sensitivity cardiac troponin I measurement for risk stratification in a stable high-risk population PA Kavsak, L Xu, S Yusuf, MJ McQueen Clinical chemistry 57 (8), 1146-1153, 2011 | 115 | 2011 |
| High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study PA Kavsak, M Walsh, S Srinathan, L Thorlacius, GL Buse, F Botto, S Pettit, ... Clinical biochemistry 44 (12), 1021-1024, 2011 | 105 | 2011 |
| Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction JW Pickering, JH Greenslade, L Cullen, D Flaws, W Parsonage, P George, ... Heart 102 (16), 1270-1278, 2016 | 102 | 2016 |
