The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 670 | 2014 |
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor AS Krall, S Xu, TG Graeber, D Braas, HR Christofk Nature communications 7 (1), 1-13, 2016 | 506 | 2016 |
Lactate dehydrogenase activity drives hair follicle stem cell activation A Flores, J Schell, AS Krall, D Jelinek, M Miranda, M Grigorian, D Braas, ... Nature cell biology 19 (9), 1017-1026, 2017 | 278 | 2017 |
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth AS Krall, PJ Mullen, F Surjono, M Momcilovic, EW Schmid, CJ Halbrook, ... Cell metabolism 33 (5), 1013-1026. e6, 2021 | 204 | 2021 |
Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy CK Domigan, CM Warren, V Antanesian, K Happel, S Ziyad, S Lee, ... Journal of cell science 128 (12), 2236-2248, 2015 | 190 | 2015 |
Stimulation of histone deacetylase activity by metabolites of intermediary metabolism M Vogelauer, AS Krall, MA McBrian, JY Li, SK Kurdistani Journal of Biological Chemistry 287 (38), 32006-32016, 2012 | 90 | 2012 |
Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin A Flores, S Sandoval-Gonzalez, R Takahashi, A Krall, L Sathe, L Wei, ... Nature communications 10 (1), 91, 2019 | 45 | 2019 |
Rethinking glutamine addiction AS Krall, HR Christofk Nature cell biology 17 (12), 1515-1517, 2015 | 44 | 2015 |
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells CJ Halbrook, G Thurston, S Boyer, C Anaraki, JA Jiménez, A McCarthy, ... Nature cancer 3 (11), 1386-1403, 2022 | 41 | 2022 |
Division enzyme regulates metabolism AS Krall, HR Christofk Nature 546 (7658), 357-358, 2017 | 28 | 2017 |
ZFP36-mediated mRNA decay regulates metabolism AC Cicchetto, EC Jacobson, H Sunshine, BR Wilde, AS Krall, KE Jarrett, ... Cell reports 42 (5), 2023 | 16 | 2023 |
A metabolic metamorphosis AS Krall, HR Christofk Nature 496 (7443), 38-40, 2013 | 16 | 2013 |
Clonal heterogeneity supports mitochondrial metabolism in pancreatic cancer CJ Halbrook, G Thurston, A McCarthy, BS Nelson, P Sajjakulnukit, ... Biorxiv, 2020.05. 15.098368, 2020 | 9 | 2020 |
Asparagine signals mitochondrial respiration and can be targeted to impair tumour growth AS Krall, PJ Mullen, F Surjono, M Momcilovic, EW Schmid, CJ Halbrook, ... bioRxiv, 2020.03. 17.995670, 2020 | 4 | 2020 |
Levocarnitine does not impair chemotherapy cytotoxicity against acute lymphoblastic leukemia JL Sea, E Orgel, T Chen, RL Paszkiewicz, AS Krall, MJ Oberley, L Stiles, ... Leukemia & lymphoma 61 (2), 420-428, 2020 | 4 | 2020 |
Metabolite Signaling Mediates Cellular Homeostasis and Proliferation A Krall UCLA, 2018 | | 2018 |
Publication Year: 2012 M Vogelauer, AS Krall, MA McBrian, JY Li, SK Kurdistani | | 2012 |