Ligand and target discovery by fragment-based screening in human cells CG Parker, A Galmozzi, Y Wang, BE Correia, K Sasaki, CM Joslyn, ... Cell 168 (3), 527-541. e29, 2017 | 382 | 2017 |
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue A Galmozzi, N Mitro, A Ferrari, E Gers, F Gilardi, C Godio, G Cermenati, ... diabetes 62 (3), 732-742, 2013 | 252 | 2013 |
Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue W Chen, J Dong, L Plate, DE Mortenson, GJ Brighty, S Li, Y Liu, ... Journal of the American Chemical Society 138 (23), 7353-7364, 2016 | 233 | 2016 |
Study of 1, 4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors A Mai, S Valente, S Meade, V Carafa, M Tardugno, A Nebbioso, ... Journal of medicinal chemistry 52 (17), 5496-5504, 2009 | 184 | 2009 |
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes E Dominguez, A Galmozzi, JW Chang, KL Hsu, J Pawlak, W Li, C Godio, ... Nature chemical biology 10 (2), 113-121, 2014 | 143 | 2014 |
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor γ ligand-binding domain in the complex with two … G Pochetti, C Godio, N Mitro, D Caruso, A Galmozzi, S Scurati, F Loiodice, ... Journal of Biological Chemistry 282 (23), 17314-17324, 2007 | 141 | 2007 |
ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue A Galmozzi, SB Sonne, S Altshuler-Keylin, Y Hasegawa, K Shinoda, ... Cell reports 9 (5), 1584-1593, 2014 | 117 | 2014 |
PGRMC2 is an intracellular haem chaperone critical for adipocyte function A Galmozzi, BP Kok, AS Kim, JR Montenegro-Burke, JY Lee, R Spreafico, ... Nature 576 (7785), 138-142, 2019 | 103 | 2019 |
Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits BP Kok, A Galmozzi, NK Littlejohn, V Albert, C Godio, W Kim, SM Kim, ... Molecular metabolism 16, 76-87, 2018 | 100 | 2018 |
Insights in the regulation of cholesterol 7α‐hydroxylase gene reveal a target for modulating bile acid synthesis N Mitro, C Godio, E De Fabiani, E Scotti, A Galmozzi, F Gilardi, D Caruso, ... Hepatology 46 (3), 885-897, 2007 | 74 | 2007 |
Linking epigenetics to lipid metabolism: focus on histone deacetylases A Ferrari, E Fiorino, M Giudici, F Gilardi, A Galmozzi, N Mitro, G Cermenati, ... Molecular membrane biology 29 (7), 257-266, 2012 | 59 | 2012 |
Chemical proteomics identifies SLC25A20 as a functional target of the ingenol class of actinic keratosis drugs CG Parker, CA Kuttruff, A Galmozzi, L Jørgensen, CH Yeh, DJ Hermanson, ... ACS Central Science 3 (12), 1276-1285, 2017 | 58 | 2017 |
Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity A Madhavan, BP Kok, B Rius, JMD Grandjean, A Alabi, V Albert, ... Nature communications 13 (1), 608, 2022 | 49 | 2022 |
Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling F Gilardi, B Viviani, A Galmozzi, M Boraso, S Bartesaghi, A Torri, ... Neuroscience 164 (2), 530-540, 2009 | 42 | 2009 |
Discovery of small-molecule enzyme activators by activity-based protein profiling BP Kok, S Ghimire, W Kim, S Chatterjee, T Johns, S Kitamura, J Eberhardt, ... Nature chemical biology 16 (9), 997-1005, 2020 | 36 | 2020 |
Application of activity-based protein profiling to study enzyme function in adipocytes A Galmozzi, E Dominguez, BF Cravatt, E Saez Methods in enzymology 538, 151-169, 2014 | 33 | 2014 |
Activation of kappa opioid receptor regulates the hypothermic response to calorie restriction and limits body weight loss R Cintron-Colon, CW Johnson, JR Montenegro-Burke, C Guijas, ... Current Biology 29 (24), 4291-4299. e4, 2019 | 30 | 2019 |
Effect of different dietary fats on hepatic gene expression in transition dairy goats A Agazzi, G Invernizzi, A Campagnoli, M Ferroni, A Fanelli, D Cattaneo, ... Small Ruminant Research 93 (1), 31-40, 2010 | 29 | 2010 |
Reactive oxygen species scavenger N-acetyl cysteine reduces methamphetamine-induced hyperthermia without affecting motor activity in mice M Sanchez-Alavez, N Bortell, A Galmozzi, B Conti, MCG Marcondes Temperature 1 (3), 227-241, 2014 | 26 | 2014 |
Metabolomics activity screening of T cell–induced colitis reveals anti-inflammatory metabolites JR Montenegro-Burke, BP Kok, C Guijas, X Domingo-Almenara, C Moon, ... Science signaling 14 (702), eabf6584, 2021 | 24 | 2021 |