Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality S Hirotsune, MW Fleck, MJ Gambello, GJ Bix, A Chen, GD Clark, ... Nature genetics 19 (4), 333-339, 1998 | 634 | 1998 |
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin G Bix, J Fu, EM Gonzalez, L Macro, A Barker, S Campbell, MM Zutter, ... The Journal of cell biology 166 (1), 97-109, 2004 | 331 | 2004 |
Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis JX Zhu, S Goldoni, G Bix, RT Owens, DJ McQuillan, CC Reed, RV Iozzo Journal of Biological Chemistry 280 (37), 32468-32479, 2005 | 224 | 2005 |
BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan EM Gonzalez, CC Reed, G Bix, J Fu, Y Zhang, B Gopalakrishnan, ... Journal of Biological Chemistry 280 (8), 7080-7087, 2005 | 223 | 2005 |
Matrix revolutions:‘tails’ of basement-membrane components with angiostatic functions G Bix, RV Iozzo Trends in cell biology 15 (1), 52-60, 2005 | 168 | 2005 |
Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents B Lee, D Clarke, A Al Ahmad, M Kahle, C Parham, L Auckland, C Shaw, ... The Journal of clinical investigation 121 (8), 3005-3023, 2011 | 167 | 2011 |
Understanding history, and not repeating it. Neuroprotection for acute ischemic stroke: from review to preview S Grupke, J Hall, M Dobbs, GJ Bix, JF Fraser Clinical neurology and neurosurgery 129, 1-9, 2015 | 137 | 2015 |
Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism G Bix, R Castello, M Burrows, JJ Zoeller, M Weech, RA Iozzo, C Cardi, ... Journal of the National Cancer Institute 98 (22), 1634-1646, 2006 | 135 | 2006 |
Platelet-activating factor receptor stimulation disrupts neuronal migration in vitro GJ Bix, GD Clark Journal of Neuroscience 18 (1), 307-318, 1998 | 123 | 1998 |
SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders N Amruta, WH Chastain, M Paz, RJ Solch, IC Murray-Brown, JB Befeler, ... Cytokine & growth factor reviews 58, 1-15, 2021 | 122 | 2021 |
Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates I Rutkai, MG Mayer, LM Hellmers, B Ning, Z Huang, CJ Monjure, C Coyne, ... Nature communications 13 (1), 1745, 2022 | 119 | 2022 |
Novel interactions of perlecan: unraveling perlecan's role in angiogenesis G Bix, RV Iozzo Microscopy research and technique 71 (5), 339-348, 2008 | 116 | 2008 |
Neurogenesis after stroke: a therapeutic perspective AA Rahman, N Amruta, E Pinteaux, GJ Bix Translational stroke research 12 (1), 1-14, 2021 | 95 | 2021 |
The integrin binding peptide, ATN-161, as a novel therapy for SARS-CoV-2 infection BJ Beddingfield, N Iwanaga, PP Chapagain, W Zheng, CJ Roy, TY Hu, ... Basic to Translational Science 6 (1), 1-8, 2021 | 83 | 2021 |
Biomarker application for precision medicine in stroke AN Simpkins, M Janowski, HS Oz, J Roberts, G Bix, S Doré, AM Stowe Translational stroke research 11, 615-627, 2020 | 80 | 2020 |
Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the α2β1-integrin receptor G Bix, RA Iozzo, B Woodall, M Burrows, A McQuillan, S Campbell, ... Blood 109 (9), 3745-3748, 2007 | 78 | 2007 |
Perlecan and the blood-brain barrier: beneficial proteolysis? J Roberts, MP Kahle, GJ Bix Frontiers in pharmacology 3, 155, 2012 | 74 | 2012 |
Successfully climbing the “STAIRs”: surmounting failed translation of experimental ischemic stroke treatments MP Kahle, GJ Bix Stroke research and treatment 2012 (1), 374098, 2012 | 74 | 2012 |
Roles of blood-brain barrier integrins and extracellular matrix in stroke DN Edwards, GJ Bix American Journal of Physiology-Cell Physiology 316 (2), C252-C263, 2019 | 69 | 2019 |
Perlecan Domain V Induces VEGf Secretion in Brain Endothelial Cells through Integrin α5β1 and ERK-Dependent Signaling Pathways DN Clarke, A Al Ahmad, B Lee, C Parham, L Auckland, A Fertala, M Kahle, ... Public Library of Science 7 (9), e45257, 2012 | 58 | 2012 |